Evaluation of C-ErbB-2 Overexpression and Her-2/neu Gene Copy Number Heterogeneity in Barrett’s Adenocarcinoma

Evaluation of C-ErbB-2 Overexpression and Her-2/neu Gene Copy Number Heterogeneity in Barrett’s Adenocarcinoma

Amplifiction of the Her-2/neu gene is accompanied by overexpression of its cell surface receptor product, c‐erbB‐2 protein. To investigate the degree of intratumoural heterogeneity we applied immunohistochemistry in primary Barrett’s adenocarcinoma (BCA) (n = 6) and dysplasia adjacent to the carcino...

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Bibliographic Details
Main Authors:	Axel Walch, Karin Bink, Peter Gais, Stefan Stangl, Peter Hutzler, Michaela Aubele, James Mueller, Heinz Höfler, Martin Werner
Format:	Article
Language:	English
Published:	Wiley 2000-01-01
Series:	Analytical Cellular Pathology
Online Access:	http://dx.doi.org/10.1155/2000/947249
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