High-Risk Esophageal GIST: Imaging and Therapeutic Impact on Atypical Metastatic Lesions

This case represents a relatively rare localization of a gastrointestinal stromal tumor involving the distal esophagus with a very unusual mode of metastatic spread to the lymph nodes and bone structures. Diagnostic follow-up showed the effect of tyrosine kinase inhibitor therapy on metastatic lesio...

Full description

Saved in:
Bibliographic Details
Main Authors: Predrag Sabljak, Aleksandra Djuric-Stefanovic, Miljana Bubanja, Strahinja Odalovic, Nenad Ivanovic, Milica Mitrovic-Jovanovic, Ognjan Skrobic
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Diagnostics
Subjects:
Online Access:https://www.mdpi.com/2075-4418/15/14/1802
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849521429193687040
author Predrag Sabljak
Aleksandra Djuric-Stefanovic
Miljana Bubanja
Strahinja Odalovic
Nenad Ivanovic
Milica Mitrovic-Jovanovic
Ognjan Skrobic
author_facet Predrag Sabljak
Aleksandra Djuric-Stefanovic
Miljana Bubanja
Strahinja Odalovic
Nenad Ivanovic
Milica Mitrovic-Jovanovic
Ognjan Skrobic
author_sort Predrag Sabljak
collection DOAJ
description This case represents a relatively rare localization of a gastrointestinal stromal tumor involving the distal esophagus with a very unusual mode of metastatic spread to the lymph nodes and bone structures. Diagnostic follow-up showed the effect of tyrosine kinase inhibitor therapy on metastatic lesions, highlighting the necessity of comprehensive diagnostic evaluation in patients with atypical presentations and contributing to the improvement of therapeutic strategies in complex clinical scenarios.
format Article
id doaj-art-0492b8e103384ded8d0a554da2f0ab0f
institution Kabale University
issn 2075-4418
language English
publishDate 2025-07-01
publisher MDPI AG
record_format Article
series Diagnostics
spelling doaj-art-0492b8e103384ded8d0a554da2f0ab0f2025-08-20T03:32:26ZengMDPI AGDiagnostics2075-44182025-07-011514180210.3390/diagnostics15141802High-Risk Esophageal GIST: Imaging and Therapeutic Impact on Atypical Metastatic LesionsPredrag Sabljak0Aleksandra Djuric-Stefanovic1Miljana Bubanja2Strahinja Odalovic3Nenad Ivanovic4Milica Mitrovic-Jovanovic5Ognjan Skrobic6Clinic for Digestive Surgery, University Clinical Centre of Serbia, Koste Todorovica Street, No. 6, 11000 Belgrade, SerbiaFaculty of Medicine, University of Belgrade, Dr Subotica No. 8, 11000 Belgrade, SerbiaCenter for Radiology and Magnetic Resonance Imaging, University Clinical Centre of Serbia, Pasterova No. 2, 11000 Belgrade, SerbiaFaculty of Medicine, University of Belgrade, Dr Subotica No. 8, 11000 Belgrade, SerbiaClinic for Digestive Surgery, University Clinical Centre of Serbia, Koste Todorovica Street, No. 6, 11000 Belgrade, SerbiaFaculty of Medicine, University of Belgrade, Dr Subotica No. 8, 11000 Belgrade, SerbiaClinic for Digestive Surgery, University Clinical Centre of Serbia, Koste Todorovica Street, No. 6, 11000 Belgrade, SerbiaThis case represents a relatively rare localization of a gastrointestinal stromal tumor involving the distal esophagus with a very unusual mode of metastatic spread to the lymph nodes and bone structures. Diagnostic follow-up showed the effect of tyrosine kinase inhibitor therapy on metastatic lesions, highlighting the necessity of comprehensive diagnostic evaluation in patients with atypical presentations and contributing to the improvement of therapeutic strategies in complex clinical scenarios.https://www.mdpi.com/2075-4418/15/14/1802gastrointestinal stromal tumorsesophagusGIST metastasestyrosine kinase inhibitors
spellingShingle Predrag Sabljak
Aleksandra Djuric-Stefanovic
Miljana Bubanja
Strahinja Odalovic
Nenad Ivanovic
Milica Mitrovic-Jovanovic
Ognjan Skrobic
High-Risk Esophageal GIST: Imaging and Therapeutic Impact on Atypical Metastatic Lesions
Diagnostics
gastrointestinal stromal tumors
esophagus
GIST metastases
tyrosine kinase inhibitors
title High-Risk Esophageal GIST: Imaging and Therapeutic Impact on Atypical Metastatic Lesions
title_full High-Risk Esophageal GIST: Imaging and Therapeutic Impact on Atypical Metastatic Lesions
title_fullStr High-Risk Esophageal GIST: Imaging and Therapeutic Impact on Atypical Metastatic Lesions
title_full_unstemmed High-Risk Esophageal GIST: Imaging and Therapeutic Impact on Atypical Metastatic Lesions
title_short High-Risk Esophageal GIST: Imaging and Therapeutic Impact on Atypical Metastatic Lesions
title_sort high risk esophageal gist imaging and therapeutic impact on atypical metastatic lesions
topic gastrointestinal stromal tumors
esophagus
GIST metastases
tyrosine kinase inhibitors
url https://www.mdpi.com/2075-4418/15/14/1802
work_keys_str_mv AT predragsabljak highriskesophagealgistimagingandtherapeuticimpactonatypicalmetastaticlesions
AT aleksandradjuricstefanovic highriskesophagealgistimagingandtherapeuticimpactonatypicalmetastaticlesions
AT miljanabubanja highriskesophagealgistimagingandtherapeuticimpactonatypicalmetastaticlesions
AT strahinjaodalovic highriskesophagealgistimagingandtherapeuticimpactonatypicalmetastaticlesions
AT nenadivanovic highriskesophagealgistimagingandtherapeuticimpactonatypicalmetastaticlesions
AT milicamitrovicjovanovic highriskesophagealgistimagingandtherapeuticimpactonatypicalmetastaticlesions
AT ognjanskrobic highriskesophagealgistimagingandtherapeuticimpactonatypicalmetastaticlesions