Acute Heart Failure as a First Manifestation of Primary Adrenal Insufficiency: Highly Lethal If Not Diagnosed!

Background. Primary adrenal insufficiency is an uncommon condition that manifests as nonspecific symptoms such as fatigue, weight loss, salt craving, and hyperpigmentation. Common cardiovascular presentations of AI are hypotension, arrhythmias, and syncope. However, acute heart failure is an uncommo...

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Main Authors: Maryam Heidarpour, Mohammad Mehdi Zare, Shiva Armani, Hedie Torkashvan, Sadegh Mazaheri-Tehrani, Davood Shafie
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Case Reports in Endocrinology
Online Access:http://dx.doi.org/10.1155/2024/5759629
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author Maryam Heidarpour
Mohammad Mehdi Zare
Shiva Armani
Hedie Torkashvan
Sadegh Mazaheri-Tehrani
Davood Shafie
author_facet Maryam Heidarpour
Mohammad Mehdi Zare
Shiva Armani
Hedie Torkashvan
Sadegh Mazaheri-Tehrani
Davood Shafie
author_sort Maryam Heidarpour
collection DOAJ
description Background. Primary adrenal insufficiency is an uncommon condition that manifests as nonspecific symptoms such as fatigue, weight loss, salt craving, and hyperpigmentation. Common cardiovascular presentations of AI are hypotension, arrhythmias, and syncope. However, acute heart failure is an uncommon presentation. Case Presentation. Here, a 26-year-old man was hospitalized with vasopressor-resistant cardiogenic shock, which was finally attributed to an adrenal crisis. His past medical history was notable for Hashimoto’s disease, controlled with oral levothyroxine. Conclusion. AI should be considered among patients with cardiogenic shock who are unresponsive to conventional inotropes. Additionally, a history of autoimmune diseases may increase the suspicion of AI. Although the presentation of cardiogenic shock in a patient with undiagnosed AI is considered a rarity, delay in prompt treatment can lead to life-threatening conditions.
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institution Kabale University
issn 2090-651X
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publishDate 2024-01-01
publisher Wiley
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series Case Reports in Endocrinology
spelling doaj-art-0480c68d72a4462a825b3c383d59c9722025-02-03T07:23:47ZengWileyCase Reports in Endocrinology2090-651X2024-01-01202410.1155/2024/5759629Acute Heart Failure as a First Manifestation of Primary Adrenal Insufficiency: Highly Lethal If Not Diagnosed!Maryam Heidarpour0Mohammad Mehdi Zare1Shiva Armani2Hedie Torkashvan3Sadegh Mazaheri-Tehrani4Davood Shafie5Isfahan Endocrine and Metabolism Research CenterIsfahan Endocrine and Metabolism Research CenterHeart Failure Research CenterHeart Failure Research CenterHeart Failure Research CenterHeart Failure Research CenterBackground. Primary adrenal insufficiency is an uncommon condition that manifests as nonspecific symptoms such as fatigue, weight loss, salt craving, and hyperpigmentation. Common cardiovascular presentations of AI are hypotension, arrhythmias, and syncope. However, acute heart failure is an uncommon presentation. Case Presentation. Here, a 26-year-old man was hospitalized with vasopressor-resistant cardiogenic shock, which was finally attributed to an adrenal crisis. His past medical history was notable for Hashimoto’s disease, controlled with oral levothyroxine. Conclusion. AI should be considered among patients with cardiogenic shock who are unresponsive to conventional inotropes. Additionally, a history of autoimmune diseases may increase the suspicion of AI. Although the presentation of cardiogenic shock in a patient with undiagnosed AI is considered a rarity, delay in prompt treatment can lead to life-threatening conditions.http://dx.doi.org/10.1155/2024/5759629
spellingShingle Maryam Heidarpour
Mohammad Mehdi Zare
Shiva Armani
Hedie Torkashvan
Sadegh Mazaheri-Tehrani
Davood Shafie
Acute Heart Failure as a First Manifestation of Primary Adrenal Insufficiency: Highly Lethal If Not Diagnosed!
Case Reports in Endocrinology
title Acute Heart Failure as a First Manifestation of Primary Adrenal Insufficiency: Highly Lethal If Not Diagnosed!
title_full Acute Heart Failure as a First Manifestation of Primary Adrenal Insufficiency: Highly Lethal If Not Diagnosed!
title_fullStr Acute Heart Failure as a First Manifestation of Primary Adrenal Insufficiency: Highly Lethal If Not Diagnosed!
title_full_unstemmed Acute Heart Failure as a First Manifestation of Primary Adrenal Insufficiency: Highly Lethal If Not Diagnosed!
title_short Acute Heart Failure as a First Manifestation of Primary Adrenal Insufficiency: Highly Lethal If Not Diagnosed!
title_sort acute heart failure as a first manifestation of primary adrenal insufficiency highly lethal if not diagnosed
url http://dx.doi.org/10.1155/2024/5759629
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