Assessment of the feed additive consisting of robenidine hydrochloride (Cycostat® 66G) for rabbits for breeding and rabbits for fattening for the renewal of its authorisation (Zoetis)
Abstract Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the feed additive consisting of robenidine hydrochloride (Cycostat® 66G) for rabbits for breeding and rabbits for fat...
Saved in:
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2023-03-01
|
| Series: | EFSA Journal |
| Subjects: | |
| Online Access: | https://doi.org/10.2903/j.efsa.2023.7863 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850149266521063424 |
|---|---|
| author | EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) Vasileios Bampidis Giovanna Azimonti Maria de Lourdes Bastos Henrik Christensen Birgit Dusemund Mojca Durjava Maryline Kouba Marta López‐Alonso Secundino López Puente Francesca Marcon Baltasar Mayo Alena Pechová Mariana Petkova Fernando Ramos Yolanda Sanz Roberto Edoardo Villa Ruud Woutersen Jürgen Gropp Guido Rychen Orsolya Holczknecht Barbara Rossi Maria Vittoria Vettori |
| author_facet | EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) Vasileios Bampidis Giovanna Azimonti Maria de Lourdes Bastos Henrik Christensen Birgit Dusemund Mojca Durjava Maryline Kouba Marta López‐Alonso Secundino López Puente Francesca Marcon Baltasar Mayo Alena Pechová Mariana Petkova Fernando Ramos Yolanda Sanz Roberto Edoardo Villa Ruud Woutersen Jürgen Gropp Guido Rychen Orsolya Holczknecht Barbara Rossi Maria Vittoria Vettori |
| author_sort | EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) |
| collection | DOAJ |
| description | Abstract Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the feed additive consisting of robenidine hydrochloride (Cycostat® 66G) for rabbits for breeding and rabbits for fattening for the renewal of its authorisation. Since the potential aneugenic activity of robenidine hydrochloride cannot be excluded, the FEEDAP Panel is not in the position to conclude on the safety of the additive for the target species and the consumer. In the absence of data, the FEEDAP Panel cannot conclude on the safety of robenidine hydrochloride for the environment. Robenidine hydrochloride has potential for bioaccumulation; however, a risk for secondary poisoning for worm/fish‐eating birds and mammals is not likely to occur. No concern for groundwater is expected. Robenidine hydrochloride is not a skin or eye irritant and not a skin sensitiser. Due to the lack of data on the genotoxicity (aneugenicity) of the substance, the exposure to the additive of the unprotected users should be minimised. Owing to the lack of sufficient data, the FEEDAP Panel cannot conclude that robenidine hydrochloride from Cycostat® 66G is still efficacious against recent Eimeria spp. strains in rabbits. |
| format | Article |
| id | doaj-art-04730a9b544f4bfc846e3aff8346bb97 |
| institution | OA Journals |
| issn | 1831-4732 |
| language | English |
| publishDate | 2023-03-01 |
| publisher | Wiley |
| record_format | Article |
| series | EFSA Journal |
| spelling | doaj-art-04730a9b544f4bfc846e3aff8346bb972025-08-20T02:26:59ZengWileyEFSA Journal1831-47322023-03-01213n/an/a10.2903/j.efsa.2023.7863Assessment of the feed additive consisting of robenidine hydrochloride (Cycostat® 66G) for rabbits for breeding and rabbits for fattening for the renewal of its authorisation (Zoetis)EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)Vasileios BampidisGiovanna AzimontiMaria de Lourdes BastosHenrik ChristensenBirgit DusemundMojca DurjavaMaryline KoubaMarta López‐AlonsoSecundino López PuenteFrancesca MarconBaltasar MayoAlena PechováMariana PetkovaFernando RamosYolanda SanzRoberto Edoardo VillaRuud WoutersenJürgen GroppGuido RychenOrsolya HolczknechtBarbara RossiMaria Vittoria VettoriAbstract Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the feed additive consisting of robenidine hydrochloride (Cycostat® 66G) for rabbits for breeding and rabbits for fattening for the renewal of its authorisation. Since the potential aneugenic activity of robenidine hydrochloride cannot be excluded, the FEEDAP Panel is not in the position to conclude on the safety of the additive for the target species and the consumer. In the absence of data, the FEEDAP Panel cannot conclude on the safety of robenidine hydrochloride for the environment. Robenidine hydrochloride has potential for bioaccumulation; however, a risk for secondary poisoning for worm/fish‐eating birds and mammals is not likely to occur. No concern for groundwater is expected. Robenidine hydrochloride is not a skin or eye irritant and not a skin sensitiser. Due to the lack of data on the genotoxicity (aneugenicity) of the substance, the exposure to the additive of the unprotected users should be minimised. Owing to the lack of sufficient data, the FEEDAP Panel cannot conclude that robenidine hydrochloride from Cycostat® 66G is still efficacious against recent Eimeria spp. strains in rabbits.https://doi.org/10.2903/j.efsa.2023.7863Robenidine hydrochlorideCycostat® 66Grabbits for breedingrabbits for fatteningrenewal |
| spellingShingle | EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) Vasileios Bampidis Giovanna Azimonti Maria de Lourdes Bastos Henrik Christensen Birgit Dusemund Mojca Durjava Maryline Kouba Marta López‐Alonso Secundino López Puente Francesca Marcon Baltasar Mayo Alena Pechová Mariana Petkova Fernando Ramos Yolanda Sanz Roberto Edoardo Villa Ruud Woutersen Jürgen Gropp Guido Rychen Orsolya Holczknecht Barbara Rossi Maria Vittoria Vettori Assessment of the feed additive consisting of robenidine hydrochloride (Cycostat® 66G) for rabbits for breeding and rabbits for fattening for the renewal of its authorisation (Zoetis) EFSA Journal Robenidine hydrochloride Cycostat® 66G rabbits for breeding rabbits for fattening renewal |
| title | Assessment of the feed additive consisting of robenidine hydrochloride (Cycostat® 66G) for rabbits for breeding and rabbits for fattening for the renewal of its authorisation (Zoetis) |
| title_full | Assessment of the feed additive consisting of robenidine hydrochloride (Cycostat® 66G) for rabbits for breeding and rabbits for fattening for the renewal of its authorisation (Zoetis) |
| title_fullStr | Assessment of the feed additive consisting of robenidine hydrochloride (Cycostat® 66G) for rabbits for breeding and rabbits for fattening for the renewal of its authorisation (Zoetis) |
| title_full_unstemmed | Assessment of the feed additive consisting of robenidine hydrochloride (Cycostat® 66G) for rabbits for breeding and rabbits for fattening for the renewal of its authorisation (Zoetis) |
| title_short | Assessment of the feed additive consisting of robenidine hydrochloride (Cycostat® 66G) for rabbits for breeding and rabbits for fattening for the renewal of its authorisation (Zoetis) |
| title_sort | assessment of the feed additive consisting of robenidine hydrochloride cycostat r 66g for rabbits for breeding and rabbits for fattening for the renewal of its authorisation zoetis |
| topic | Robenidine hydrochloride Cycostat® 66G rabbits for breeding rabbits for fattening renewal |
| url | https://doi.org/10.2903/j.efsa.2023.7863 |
| work_keys_str_mv | AT efsapanelonadditivesandproductsorsubstancesusedinanimalfeedfeedap assessmentofthefeedadditiveconsistingofrobenidinehydrochloridecycostat66gforrabbitsforbreedingandrabbitsforfatteningfortherenewalofitsauthorisationzoetis AT vasileiosbampidis assessmentofthefeedadditiveconsistingofrobenidinehydrochloridecycostat66gforrabbitsforbreedingandrabbitsforfatteningfortherenewalofitsauthorisationzoetis AT giovannaazimonti assessmentofthefeedadditiveconsistingofrobenidinehydrochloridecycostat66gforrabbitsforbreedingandrabbitsforfatteningfortherenewalofitsauthorisationzoetis AT mariadelourdesbastos assessmentofthefeedadditiveconsistingofrobenidinehydrochloridecycostat66gforrabbitsforbreedingandrabbitsforfatteningfortherenewalofitsauthorisationzoetis AT henrikchristensen assessmentofthefeedadditiveconsistingofrobenidinehydrochloridecycostat66gforrabbitsforbreedingandrabbitsforfatteningfortherenewalofitsauthorisationzoetis AT birgitdusemund assessmentofthefeedadditiveconsistingofrobenidinehydrochloridecycostat66gforrabbitsforbreedingandrabbitsforfatteningfortherenewalofitsauthorisationzoetis AT mojcadurjava assessmentofthefeedadditiveconsistingofrobenidinehydrochloridecycostat66gforrabbitsforbreedingandrabbitsforfatteningfortherenewalofitsauthorisationzoetis AT marylinekouba assessmentofthefeedadditiveconsistingofrobenidinehydrochloridecycostat66gforrabbitsforbreedingandrabbitsforfatteningfortherenewalofitsauthorisationzoetis AT martalopezalonso assessmentofthefeedadditiveconsistingofrobenidinehydrochloridecycostat66gforrabbitsforbreedingandrabbitsforfatteningfortherenewalofitsauthorisationzoetis AT secundinolopezpuente assessmentofthefeedadditiveconsistingofrobenidinehydrochloridecycostat66gforrabbitsforbreedingandrabbitsforfatteningfortherenewalofitsauthorisationzoetis AT francescamarcon assessmentofthefeedadditiveconsistingofrobenidinehydrochloridecycostat66gforrabbitsforbreedingandrabbitsforfatteningfortherenewalofitsauthorisationzoetis AT baltasarmayo assessmentofthefeedadditiveconsistingofrobenidinehydrochloridecycostat66gforrabbitsforbreedingandrabbitsforfatteningfortherenewalofitsauthorisationzoetis AT alenapechova assessmentofthefeedadditiveconsistingofrobenidinehydrochloridecycostat66gforrabbitsforbreedingandrabbitsforfatteningfortherenewalofitsauthorisationzoetis AT marianapetkova assessmentofthefeedadditiveconsistingofrobenidinehydrochloridecycostat66gforrabbitsforbreedingandrabbitsforfatteningfortherenewalofitsauthorisationzoetis AT fernandoramos assessmentofthefeedadditiveconsistingofrobenidinehydrochloridecycostat66gforrabbitsforbreedingandrabbitsforfatteningfortherenewalofitsauthorisationzoetis AT yolandasanz assessmentofthefeedadditiveconsistingofrobenidinehydrochloridecycostat66gforrabbitsforbreedingandrabbitsforfatteningfortherenewalofitsauthorisationzoetis AT robertoedoardovilla assessmentofthefeedadditiveconsistingofrobenidinehydrochloridecycostat66gforrabbitsforbreedingandrabbitsforfatteningfortherenewalofitsauthorisationzoetis AT ruudwoutersen assessmentofthefeedadditiveconsistingofrobenidinehydrochloridecycostat66gforrabbitsforbreedingandrabbitsforfatteningfortherenewalofitsauthorisationzoetis AT jurgengropp assessmentofthefeedadditiveconsistingofrobenidinehydrochloridecycostat66gforrabbitsforbreedingandrabbitsforfatteningfortherenewalofitsauthorisationzoetis AT guidorychen assessmentofthefeedadditiveconsistingofrobenidinehydrochloridecycostat66gforrabbitsforbreedingandrabbitsforfatteningfortherenewalofitsauthorisationzoetis AT orsolyaholczknecht assessmentofthefeedadditiveconsistingofrobenidinehydrochloridecycostat66gforrabbitsforbreedingandrabbitsforfatteningfortherenewalofitsauthorisationzoetis AT barbararossi assessmentofthefeedadditiveconsistingofrobenidinehydrochloridecycostat66gforrabbitsforbreedingandrabbitsforfatteningfortherenewalofitsauthorisationzoetis AT mariavittoriavettori assessmentofthefeedadditiveconsistingofrobenidinehydrochloridecycostat66gforrabbitsforbreedingandrabbitsforfatteningfortherenewalofitsauthorisationzoetis |