From molecular mechanism to plant intervention: the bidirectional regulation of inflammation and oxidative stress in bone aging

From molecular mechanism to plant intervention: the bidirectional regulation of inflammation and oxidative stress in bone aging

This article systematically elaborates the central role of inflammatory response and oxidative stress in osteoporosis (OP) and cartilage injury, and reveals the molecular mechanism by which the two damage bone homeostasis through NF-κB, RANKL and other signaling pathways. Studies have shown that pla...

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Bibliographic Details
Main Authors: Qi Li, Xiumei Zhao, Anning Wang, Tingting Hang, Jianpeng Zhao, Shengkai Zhang, Lingfeng Zeng, Weiguo Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Endocrinology
Subjects:
osteoporosis
bone aging
cartilage injury
inflammatory response
oxidative stress
signaling pathways
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2025.1634580/full
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