Efficacy and safety of sarilumab in combination with methotrexate in patients with active rheumatoid arthritis and inadequate effect of methotrexate monotherapy (results of phase III MOBILITY study)

Efficacy and safety of sarilumab in combination with methotrexate in patients with active rheumatoid arthritis and inadequate effect of methotrexate monotherapy (results of phase III MOBILITY study)

Objective: to study the efficacy and safety of rheumatoid arthritis (RA) treatment with monoclonal antibodies to interleukin 6 receptors (IL6R) – sarilumab (SAR) in combination with methotrexate (MT).Subjects and methods. The study included adult patients with moderate or severe RA and inadequate ef...

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Main Authors: E. L. Nasonov, M. L. Stanislav, T. A. Raskina, G. V. Kuropatkin, I. V. Shirinsky, A. P. Rebrov, N. A. Shostak, B. A. Alikhanov, E. N. Ushakov, R. G. Kamalova, S. A. Smakotina, V. I. Simanenkov, A. S. Pavsun, I. I. Zaharjan, S. S. Yakushin, M. Yu. Sandin
Format: Article
Language:Russian
Published: IMA PRESS LLC 2019-05-01
Series:Научно-практическая ревматология
Subjects:
rheumatoid arthritis
interleukin 6
sarilumab
Online Access:https://rsp.mediar-press.net/rsp/article/view/2696
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