Unlocking the Potential of Perillaldehyde: A Novel Mechanism for Chronic Myeloid Leukemia by Targeting HSP70

Unlocking the Potential of Perillaldehyde: A Novel Mechanism for Chronic Myeloid Leukemia by Targeting HSP70

Leukemia is a malignant tumor of the hematopoietic system. Approximately 15% of adult leukemias are chronic myeloid leukemias (CMLs), and this incidence increases annually. The BCR-ABL oncoprotein drives the initiation, promotion, and progression of CML. Although tyrosine kinase inhibitors (TKIs) ar...

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Bibliographic Details
Main Authors: Miaomiao Zhang, Jinfeng Wang, Rongsong Jiang, Ming Liu, Weiyi Zhang
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Molecules
Subjects:
perillaldehyde
chronic myeloid leukemia
apoptosis
autophagy
HSP70
Online Access:https://www.mdpi.com/1420-3049/30/11/2294
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