Stable recurrent dynamics in heterogeneous neuromorphic computing systems using excitatory and inhibitory plasticity

Abstract Many neural computations emerge from self-sustained patterns of activity in recurrent neural circuits, which rely on balanced excitation and inhibition. Neuromorphic electronic circuits represent a promising approach for implementing the brain’s computational primitives. However, achieving...

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Main Authors: Maryada, Saray Soldado-Magraner, Martino Sorbaro, Rodrigo Laje, Dean V. Buonomano, Giacomo Indiveri
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-60697-2
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author Maryada
Saray Soldado-Magraner
Martino Sorbaro
Rodrigo Laje
Dean V. Buonomano
Giacomo Indiveri
author_facet Maryada
Saray Soldado-Magraner
Martino Sorbaro
Rodrigo Laje
Dean V. Buonomano
Giacomo Indiveri
author_sort Maryada
collection DOAJ
description Abstract Many neural computations emerge from self-sustained patterns of activity in recurrent neural circuits, which rely on balanced excitation and inhibition. Neuromorphic electronic circuits represent a promising approach for implementing the brain’s computational primitives. However, achieving the same robustness of biological networks in neuromorphic systems remains a challenge due to the variability in their analog components. Inspired by real cortical networks, we apply a biologically-plausible cross-homeostatic rule to balance neuromorphic implementations of spiking recurrent networks. We demonstrate how this rule can autonomously tune the network to produce robust, self-sustained dynamics in an inhibition-stabilized regime, even in presence of device mismatch. It can implement multiple, co-existing stable memories, with emergent soft-winner-take-all and reproduce the “paradoxical effect” observed in cortical circuits. In addition to validating neuroscience models on a substrate sharing many similar limitations with biological systems, this enables the automatic configuration of ultra-low power, mixed-signal neuromorphic technologies despite the large chip-to-chip variability.
format Article
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institution Kabale University
issn 2041-1723
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publishDate 2025-07-01
publisher Nature Portfolio
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series Nature Communications
spelling doaj-art-045f3121f9c74a23adfe5ebecdc80bed2025-08-20T04:01:41ZengNature PortfolioNature Communications2041-17232025-07-0116111310.1038/s41467-025-60697-2Stable recurrent dynamics in heterogeneous neuromorphic computing systems using excitatory and inhibitory plasticityMaryada0Saray Soldado-Magraner1Martino Sorbaro2Rodrigo Laje3Dean V. Buonomano4Giacomo Indiveri5Institute of Neuroinformatics, University of Zurich and ETH ZurichDepartment of Neurobiology, University of CaliforniaInstitute of Neuroinformatics, University of Zurich and ETH ZurichDepartment of Science and Technology, Universidad Nacional de QuilmesDepartment of Neurobiology, University of CaliforniaInstitute of Neuroinformatics, University of Zurich and ETH ZurichAbstract Many neural computations emerge from self-sustained patterns of activity in recurrent neural circuits, which rely on balanced excitation and inhibition. Neuromorphic electronic circuits represent a promising approach for implementing the brain’s computational primitives. However, achieving the same robustness of biological networks in neuromorphic systems remains a challenge due to the variability in their analog components. Inspired by real cortical networks, we apply a biologically-plausible cross-homeostatic rule to balance neuromorphic implementations of spiking recurrent networks. We demonstrate how this rule can autonomously tune the network to produce robust, self-sustained dynamics in an inhibition-stabilized regime, even in presence of device mismatch. It can implement multiple, co-existing stable memories, with emergent soft-winner-take-all and reproduce the “paradoxical effect” observed in cortical circuits. In addition to validating neuroscience models on a substrate sharing many similar limitations with biological systems, this enables the automatic configuration of ultra-low power, mixed-signal neuromorphic technologies despite the large chip-to-chip variability.https://doi.org/10.1038/s41467-025-60697-2
spellingShingle Maryada
Saray Soldado-Magraner
Martino Sorbaro
Rodrigo Laje
Dean V. Buonomano
Giacomo Indiveri
Stable recurrent dynamics in heterogeneous neuromorphic computing systems using excitatory and inhibitory plasticity
Nature Communications
title Stable recurrent dynamics in heterogeneous neuromorphic computing systems using excitatory and inhibitory plasticity
title_full Stable recurrent dynamics in heterogeneous neuromorphic computing systems using excitatory and inhibitory plasticity
title_fullStr Stable recurrent dynamics in heterogeneous neuromorphic computing systems using excitatory and inhibitory plasticity
title_full_unstemmed Stable recurrent dynamics in heterogeneous neuromorphic computing systems using excitatory and inhibitory plasticity
title_short Stable recurrent dynamics in heterogeneous neuromorphic computing systems using excitatory and inhibitory plasticity
title_sort stable recurrent dynamics in heterogeneous neuromorphic computing systems using excitatory and inhibitory plasticity
url https://doi.org/10.1038/s41467-025-60697-2
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