Early versus late-onset major depression in the elderly: a comparative study

Aims: This study aims to investigate the distinctive characteristics between elderly with early-onset and late-onset major depression with respect to sociodemographic factors, selfperceived health, cardiovascular risk factors, MMSE scores, family history of depression, depressive symptoms, melanchol...

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Main Authors: Ulrich, Luiz Eduardo Flores, Nogueira, Eduardo Lopes, Teixeira, Laura Mocellin, Ely, Luísa Scheer, Borges Filho, José Celestino, Cataldo Neto, Alfredo
Format: Article
Language:English
Published: Pontifícia Universidade Católica do Rio Grande do Sul (EDIPUCRS) 2013-01-01
Series:PAJAR - Pan American Journal of Aging Research
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Online Access:https://revistaseletronicas.pucrs.br/ojs/index.php/pajar/article/view/15790/10400
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author Ulrich, Luiz Eduardo Flores
Nogueira, Eduardo Lopes
Teixeira, Laura Mocellin
Ely, Luísa Scheer
Borges Filho, José Celestino
Cataldo Neto, Alfredo
author_facet Ulrich, Luiz Eduardo Flores
Nogueira, Eduardo Lopes
Teixeira, Laura Mocellin
Ely, Luísa Scheer
Borges Filho, José Celestino
Cataldo Neto, Alfredo
author_sort Ulrich, Luiz Eduardo Flores
collection DOAJ
description Aims: This study aims to investigate the distinctive characteristics between elderly with early-onset and late-onset major depression with respect to sociodemographic factors, selfperceived health, cardiovascular risk factors, MMSE scores, family history of depression, depressive symptoms, melancholic features, suicide risk and alcohol abuse/dependence. Methods: Cross-sectional, descriptive and analytic study, with prospective data collection, in an random sample of 348 elderly people (≥60 years old) of the Family Heath Strategy, of which were identified 90 cases of DSM-IV unipolar major depression; subjects were divided according to early or late (≥60) age at onset of depression. Results: The prevalence of major depression in the whole sample was 25. 86%. The elderly subjects with depression were mainly of early-onset (69. 14%) and female (74. 4%); the mean age in years was higher in the late-onset major depression group (p=0. 028); the groups did not differ with respect to the other factors; after multivariate analysis there was a trend toward a negative association between suicide risk and late-onset depression. Conclusion: The early or late age at onset of depressive symptoms was not associated with different profiles. The results of this paper give support to the hypothesis that earlyand late-onset major depressive disorders are clinically undistinguishable and do not represent distinct pathologies or subtypes
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publishDate 2013-01-01
publisher Pontifícia Universidade Católica do Rio Grande do Sul (EDIPUCRS)
record_format Article
series PAJAR - Pan American Journal of Aging Research
spelling doaj-art-044fabb824c540efbe910ec2bc4499002025-08-20T03:53:27ZengPontifícia Universidade Católica do Rio Grande do Sul (EDIPUCRS)PAJAR - Pan American Journal of Aging Research2357-96412013-01-0111815000452461Early versus late-onset major depression in the elderly: a comparative studyUlrich, Luiz Eduardo FloresNogueira, Eduardo LopesTeixeira, Laura MocellinEly, Luísa ScheerBorges Filho, José CelestinoCataldo Neto, AlfredoAims: This study aims to investigate the distinctive characteristics between elderly with early-onset and late-onset major depression with respect to sociodemographic factors, selfperceived health, cardiovascular risk factors, MMSE scores, family history of depression, depressive symptoms, melancholic features, suicide risk and alcohol abuse/dependence. Methods: Cross-sectional, descriptive and analytic study, with prospective data collection, in an random sample of 348 elderly people (≥60 years old) of the Family Heath Strategy, of which were identified 90 cases of DSM-IV unipolar major depression; subjects were divided according to early or late (≥60) age at onset of depression. Results: The prevalence of major depression in the whole sample was 25. 86%. The elderly subjects with depression were mainly of early-onset (69. 14%) and female (74. 4%); the mean age in years was higher in the late-onset major depression group (p=0. 028); the groups did not differ with respect to the other factors; after multivariate analysis there was a trend toward a negative association between suicide risk and late-onset depression. Conclusion: The early or late age at onset of depressive symptoms was not associated with different profiles. The results of this paper give support to the hypothesis that earlyand late-onset major depressive disorders are clinically undistinguishable and do not represent distinct pathologies or subtypeshttps://revistaseletronicas.pucrs.br/ojs/index.php/pajar/article/view/15790/10400depressãoidosos - doençasgerontologiageriatriamedicina
spellingShingle Ulrich, Luiz Eduardo Flores
Nogueira, Eduardo Lopes
Teixeira, Laura Mocellin
Ely, Luísa Scheer
Borges Filho, José Celestino
Cataldo Neto, Alfredo
Early versus late-onset major depression in the elderly: a comparative study
PAJAR - Pan American Journal of Aging Research
depressão
idosos - doenças
gerontologia
geriatria
medicina
title Early versus late-onset major depression in the elderly: a comparative study
title_full Early versus late-onset major depression in the elderly: a comparative study
title_fullStr Early versus late-onset major depression in the elderly: a comparative study
title_full_unstemmed Early versus late-onset major depression in the elderly: a comparative study
title_short Early versus late-onset major depression in the elderly: a comparative study
title_sort early versus late onset major depression in the elderly a comparative study
topic depressão
idosos - doenças
gerontologia
geriatria
medicina
url https://revistaseletronicas.pucrs.br/ojs/index.php/pajar/article/view/15790/10400
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