Pseudomembranous Colitis: Not Always Caused by Clostridium difficile
Although classically pseudomembranous colitis is caused by Clostridium difficile, it can result from several etiologies. Certain medications, chemical injury, collagenous colitis, inflammatory bowel disease, ischemia, and other infectious pathogens can reportedly cause mucosal injury and subsequent...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2014/812704 |
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| author | Derek M. Tang Nathalie H. Urrunaga Hannah De Groot Erik C. von Rosenvinge Guofeng Xie Leyla J. Ghazi |
| author_facet | Derek M. Tang Nathalie H. Urrunaga Hannah De Groot Erik C. von Rosenvinge Guofeng Xie Leyla J. Ghazi |
| author_sort | Derek M. Tang |
| collection | DOAJ |
| description | Although classically pseudomembranous colitis is caused by Clostridium difficile, it can result from several etiologies. Certain medications, chemical injury, collagenous colitis, inflammatory bowel disease, ischemia, and other infectious pathogens can reportedly cause mucosal injury and subsequent pseudomembrane formation. We present the case of a middle-aged woman with vascular disease who was incorrectly diagnosed with refractory C. difficile infection due to the presence of pseudomembranes. Further imaging, endoscopy, and careful histopathology review revealed chronic ischemia as the cause of her pseudomembranous colitis and diarrhea. This case highlights the need for gastroenterologists to consider non-C. difficile etiologies when diagnosing pseudomembranous colitis. |
| format | Article |
| id | doaj-art-044d9345e59f42f8b6d1a21e461e752a |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-044d9345e59f42f8b6d1a21e461e752a2025-08-20T03:55:23ZengWileyCase Reports in Medicine1687-96271687-96352014-01-01201410.1155/2014/812704812704Pseudomembranous Colitis: Not Always Caused by Clostridium difficileDerek M. Tang0Nathalie H. Urrunaga1Hannah De Groot2Erik C. von Rosenvinge3Guofeng Xie4Leyla J. Ghazi5Division of Gastroenterology & Hepatology, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USADivision of Gastroenterology & Hepatology, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USADivision of Gastroenterology & Hepatology, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USADivision of Gastroenterology & Hepatology, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USADivision of Gastroenterology & Hepatology, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USADivision of Gastroenterology & Hepatology, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USAAlthough classically pseudomembranous colitis is caused by Clostridium difficile, it can result from several etiologies. Certain medications, chemical injury, collagenous colitis, inflammatory bowel disease, ischemia, and other infectious pathogens can reportedly cause mucosal injury and subsequent pseudomembrane formation. We present the case of a middle-aged woman with vascular disease who was incorrectly diagnosed with refractory C. difficile infection due to the presence of pseudomembranes. Further imaging, endoscopy, and careful histopathology review revealed chronic ischemia as the cause of her pseudomembranous colitis and diarrhea. This case highlights the need for gastroenterologists to consider non-C. difficile etiologies when diagnosing pseudomembranous colitis.http://dx.doi.org/10.1155/2014/812704 |
| spellingShingle | Derek M. Tang Nathalie H. Urrunaga Hannah De Groot Erik C. von Rosenvinge Guofeng Xie Leyla J. Ghazi Pseudomembranous Colitis: Not Always Caused by Clostridium difficile Case Reports in Medicine |
| title | Pseudomembranous Colitis: Not Always Caused by Clostridium difficile |
| title_full | Pseudomembranous Colitis: Not Always Caused by Clostridium difficile |
| title_fullStr | Pseudomembranous Colitis: Not Always Caused by Clostridium difficile |
| title_full_unstemmed | Pseudomembranous Colitis: Not Always Caused by Clostridium difficile |
| title_short | Pseudomembranous Colitis: Not Always Caused by Clostridium difficile |
| title_sort | pseudomembranous colitis not always caused by clostridium difficile |
| url | http://dx.doi.org/10.1155/2014/812704 |
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