The Genus <i>Chiliadenus</i>: A Comprehensive Review of Taxonomic Aspects, Traditional Uses, Phytochemistry and Pharmacological Activities
The genus <i>Chiliadenus</i> (Asteraceae) has been traditionally used in Mediterranean medicine for its anti-inflammatory, antioxidant, and antimicrobial properties. However, scientific research on this genus remains limited, highlighting the need for a comprehensive review of its chemic...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-01-01
|
| Series: | Plants |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2223-7747/14/2/205 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832587619270131712 |
|---|---|
| author | Lucinda Villaescusa Castillo Francisco Zaragozá García Cristina Zaragozá Arnáez |
| author_facet | Lucinda Villaescusa Castillo Francisco Zaragozá García Cristina Zaragozá Arnáez |
| author_sort | Lucinda Villaescusa Castillo |
| collection | DOAJ |
| description | The genus <i>Chiliadenus</i> (Asteraceae) has been traditionally used in Mediterranean medicine for its anti-inflammatory, antioxidant, and antimicrobial properties. However, scientific research on this genus remains limited, highlighting the need for a comprehensive review of its chemical composition and pharmacological characteristics. This review compiles existing knowledge on <i>Chiliadenus</i> species, focusing on their secondary metabolites, such as flavonoids, terpenes, and essential oils, as well as associated biological activities. The findings show that the traditional therapeutic properties of <i>Chiliadenus</i> are well supported by reported pharmacological activities in previous studies, emphasizing the potential of this genus for the development of new therapeutic agents. However, the lack of comparative studies among <i>Chiliadenus</i> species and the scarcity of in vivo studies and clinical trials hinder the full realization of its therapeutic potential. Specifically, comparative studies could be key to identifying species with unique chemical profiles and understanding how variations in secondary metabolite composition may influence their pharmacological activities. This work highlights the urgent need to expand research in these areas to validate the pharmacological properties of <i>Chiliadenus</i> species for their application in modern medicine. |
| format | Article |
| id | doaj-art-044cc8aff5db4a7187854d38dac5fa6c |
| institution | Kabale University |
| issn | 2223-7747 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Plants |
| spelling | doaj-art-044cc8aff5db4a7187854d38dac5fa6c2025-01-24T13:46:45ZengMDPI AGPlants2223-77472025-01-0114220510.3390/plants14020205The Genus <i>Chiliadenus</i>: A Comprehensive Review of Taxonomic Aspects, Traditional Uses, Phytochemistry and Pharmacological ActivitiesLucinda Villaescusa Castillo0Francisco Zaragozá García1Cristina Zaragozá Arnáez2Pharmacology Unit, Biomedical Sciences Department, Faculty of Pharmacy, University of Alcalá, 28871 Alcalá de Henares, SpainPharmacology Unit, Biomedical Sciences Department, Faculty of Pharmacy, University of Alcalá, 28871 Alcalá de Henares, SpainPharmacology Unit, Biomedical Sciences Department, Faculty of Pharmacy, University of Alcalá, 28871 Alcalá de Henares, SpainThe genus <i>Chiliadenus</i> (Asteraceae) has been traditionally used in Mediterranean medicine for its anti-inflammatory, antioxidant, and antimicrobial properties. However, scientific research on this genus remains limited, highlighting the need for a comprehensive review of its chemical composition and pharmacological characteristics. This review compiles existing knowledge on <i>Chiliadenus</i> species, focusing on their secondary metabolites, such as flavonoids, terpenes, and essential oils, as well as associated biological activities. The findings show that the traditional therapeutic properties of <i>Chiliadenus</i> are well supported by reported pharmacological activities in previous studies, emphasizing the potential of this genus for the development of new therapeutic agents. However, the lack of comparative studies among <i>Chiliadenus</i> species and the scarcity of in vivo studies and clinical trials hinder the full realization of its therapeutic potential. Specifically, comparative studies could be key to identifying species with unique chemical profiles and understanding how variations in secondary metabolite composition may influence their pharmacological activities. This work highlights the urgent need to expand research in these areas to validate the pharmacological properties of <i>Chiliadenus</i> species for their application in modern medicine.https://www.mdpi.com/2223-7747/14/2/205<i>Chiliadenus</i><i>Jasonia</i>folk medicinebioactive compoundsbiological activities |
| spellingShingle | Lucinda Villaescusa Castillo Francisco Zaragozá García Cristina Zaragozá Arnáez The Genus <i>Chiliadenus</i>: A Comprehensive Review of Taxonomic Aspects, Traditional Uses, Phytochemistry and Pharmacological Activities Plants <i>Chiliadenus</i> <i>Jasonia</i> folk medicine bioactive compounds biological activities |
| title | The Genus <i>Chiliadenus</i>: A Comprehensive Review of Taxonomic Aspects, Traditional Uses, Phytochemistry and Pharmacological Activities |
| title_full | The Genus <i>Chiliadenus</i>: A Comprehensive Review of Taxonomic Aspects, Traditional Uses, Phytochemistry and Pharmacological Activities |
| title_fullStr | The Genus <i>Chiliadenus</i>: A Comprehensive Review of Taxonomic Aspects, Traditional Uses, Phytochemistry and Pharmacological Activities |
| title_full_unstemmed | The Genus <i>Chiliadenus</i>: A Comprehensive Review of Taxonomic Aspects, Traditional Uses, Phytochemistry and Pharmacological Activities |
| title_short | The Genus <i>Chiliadenus</i>: A Comprehensive Review of Taxonomic Aspects, Traditional Uses, Phytochemistry and Pharmacological Activities |
| title_sort | genus i chiliadenus i a comprehensive review of taxonomic aspects traditional uses phytochemistry and pharmacological activities |
| topic | <i>Chiliadenus</i> <i>Jasonia</i> folk medicine bioactive compounds biological activities |
| url | https://www.mdpi.com/2223-7747/14/2/205 |
| work_keys_str_mv | AT lucindavillaescusacastillo thegenusichiliadenusiacomprehensivereviewoftaxonomicaspectstraditionalusesphytochemistryandpharmacologicalactivities AT franciscozaragozagarcia thegenusichiliadenusiacomprehensivereviewoftaxonomicaspectstraditionalusesphytochemistryandpharmacologicalactivities AT cristinazaragozaarnaez thegenusichiliadenusiacomprehensivereviewoftaxonomicaspectstraditionalusesphytochemistryandpharmacologicalactivities AT lucindavillaescusacastillo genusichiliadenusiacomprehensivereviewoftaxonomicaspectstraditionalusesphytochemistryandpharmacologicalactivities AT franciscozaragozagarcia genusichiliadenusiacomprehensivereviewoftaxonomicaspectstraditionalusesphytochemistryandpharmacologicalactivities AT cristinazaragozaarnaez genusichiliadenusiacomprehensivereviewoftaxonomicaspectstraditionalusesphytochemistryandpharmacologicalactivities |