Morphometric analysis of the fascicular organisation of the optic nerve
Background/Aim. The optic nerve is anatomically observed in four segments: intrabulbar, orbital, canalicular, and cranial. According to the literature, the surface of the transversal cut of the nerve is different through it. The aim of this study was to evaluate the fascicular organisation...
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| Format: | Article |
| Language: | English |
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Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade
2015-01-01
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| Series: | Vojnosanitetski Pregled |
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| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2015/0042-84501502132R.pdf |
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| author | Radunović Miroslav Vitošević Zdravko Ćetković Mila Vuksanović-Božarić Aleksandra Radojević Nemanja Radunović Miodrag |
| author_facet | Radunović Miroslav Vitošević Zdravko Ćetković Mila Vuksanović-Božarić Aleksandra Radojević Nemanja Radunović Miodrag |
| author_sort | Radunović Miroslav |
| collection | DOAJ |
| description | Background/Aim. The optic nerve is anatomically observed in four segments:
intrabulbar, orbital, canalicular, and cranial. According to the literature,
the surface of the transversal cut of the nerve is different through it. The
aim of this study was to evaluate the fascicular organisation of the optic
nerve, throughout its three segments from the eye. Methods. Five pairs of
optic nerves, obtained from the autopsies were examined. Using Heidenhain's
(azan) staining, the cuts were prepared for microscopy. Morphometric analysis
was performed using the stereological methods for morphometric cytology - the
Weible’s testing system M42. The following measures were established: the
surface of the transverse cut of the nerve, the entire surface of fasciculi,
the entire surface of connective tissue and blood vessels, the number of
fasciculi, the surface of a single fasciculus. Results. The surface of the
transverse cut of the nerve was found to grow from the orbital to the cranial
segment, as well as the entire surface of fasciculi. While their number is
significantly lower in the cranial segment, the number of fasciculi varied
slightly between the orbital and the canalicular segment. The surface of a
single fasciculus grows from the bulb to the chiasma. There is probable a
cause to believe that this may be due to fusion of the “small” fasciculi in
the orbitocranial direction. Conclusion. There are significant differences
among the examined parameters of the different parts of the optic nerve. |
| format | Article |
| id | doaj-art-043df7d7899f427ea8aaebace49894b9 |
| institution | OA Journals |
| issn | 0042-8450 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj-art-043df7d7899f427ea8aaebace49894b92025-08-20T02:03:06ZengMinistry of Defence of the Republic of Serbia, University of Defence, BelgradeVojnosanitetski Pregled0042-84502015-01-0172213213510.2298/VSP1502132R0042-84501502132RMorphometric analysis of the fascicular organisation of the optic nerveRadunović Miroslav0Vitošević Zdravko1Ćetković Mila2Vuksanović-Božarić Aleksandra3Radojević Nemanja4Radunović Miodrag5University of Montenegro, Faculty of Medicine, Podgorica, MontenegroFaculty of Medicine, Kosovska MitrovicaFaculty of Medicine, BelgradeUniversity of Montenegro, Faculty of Medicine, Podgorica, MontenegroUniversity of Montenegro, Faculty of Medicine, Podgorica, MontenegroUniversity of Montenegro, Faculty of Medicine, Podgorica, MontenegroBackground/Aim. The optic nerve is anatomically observed in four segments: intrabulbar, orbital, canalicular, and cranial. According to the literature, the surface of the transversal cut of the nerve is different through it. The aim of this study was to evaluate the fascicular organisation of the optic nerve, throughout its three segments from the eye. Methods. Five pairs of optic nerves, obtained from the autopsies were examined. Using Heidenhain's (azan) staining, the cuts were prepared for microscopy. Morphometric analysis was performed using the stereological methods for morphometric cytology - the Weible’s testing system M42. The following measures were established: the surface of the transverse cut of the nerve, the entire surface of fasciculi, the entire surface of connective tissue and blood vessels, the number of fasciculi, the surface of a single fasciculus. Results. The surface of the transverse cut of the nerve was found to grow from the orbital to the cranial segment, as well as the entire surface of fasciculi. While their number is significantly lower in the cranial segment, the number of fasciculi varied slightly between the orbital and the canalicular segment. The surface of a single fasciculus grows from the bulb to the chiasma. There is probable a cause to believe that this may be due to fusion of the “small” fasciculi in the orbitocranial direction. Conclusion. There are significant differences among the examined parameters of the different parts of the optic nerve.http://www.doiserbia.nb.rs/img/doi/0042-8450/2015/0042-84501502132R.pdfoptic nerveautopsymicroscopyanatomy |
| spellingShingle | Radunović Miroslav Vitošević Zdravko Ćetković Mila Vuksanović-Božarić Aleksandra Radojević Nemanja Radunović Miodrag Morphometric analysis of the fascicular organisation of the optic nerve Vojnosanitetski Pregled optic nerve autopsy microscopy anatomy |
| title | Morphometric analysis of the fascicular organisation of the optic nerve |
| title_full | Morphometric analysis of the fascicular organisation of the optic nerve |
| title_fullStr | Morphometric analysis of the fascicular organisation of the optic nerve |
| title_full_unstemmed | Morphometric analysis of the fascicular organisation of the optic nerve |
| title_short | Morphometric analysis of the fascicular organisation of the optic nerve |
| title_sort | morphometric analysis of the fascicular organisation of the optic nerve |
| topic | optic nerve autopsy microscopy anatomy |
| url | http://www.doiserbia.nb.rs/img/doi/0042-8450/2015/0042-84501502132R.pdf |
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