RBP7 knockdown inhibits proliferation of human hepatocellular carcinoma and activates the p38 MAPK pathway

RBP7 knockdown inhibits proliferation of human hepatocellular carcinoma and activates the p38 MAPK pathway

BackgroundRetinoid metabolism is critical for maintaining liver homeostasis, and its dysregulation is closely associated with liver diseases. Retinol binding protein 7 (RBP7) involves in retinoids transport, particularly in liver, indicating its importance in hepatic functions. However, its specific...

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Main Authors: Jinhai Li, Huawei Zhai, Fujing Cai, Xian Zhang, Yu Zhou, Shuqun Li, Huachun Song, Haifeng Zhang, Guangzheng Sun, Minghui Zhu, Jing Yuan, Ningxin Zhang, Maolin Yan
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Oncology
Subjects:
hepatocellular carcinoma
p38
MAPK
RBP7
retinoid
cell proliferation
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1592616/full
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