Percutaneous Coronary Intervention on Saphenous Vein Graft in Second Generation Drug Eluting Stent Era
The aim of the study was to determine major adverse cardiac events (MACE) related to the percutaneous coronary intervention (PCI) on saphenous vein graft (SVG) with a second- generation drug eluting stents in patients with previous coronary artery bypass graft (CABG). The research was conducted a...
Saved in:
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Sestre Milosrdnice University hospital, Institute of Clinical Medical Research
2024-01-01
|
| Series: | Acta Clinica Croatica |
| Subjects: | |
| Online Access: | https://hrcak.srce.hr/file/481998 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849320468754989056 |
|---|---|
| author | Milenko Čanković Andrej Preveden Vladimir Ivanović Aleksandra Milovančev Milovan Petrović Mila Kovačević Tatjana Miljković Marija Bjelobrk Lazar Velicki |
| author_facet | Milenko Čanković Andrej Preveden Vladimir Ivanović Aleksandra Milovančev Milovan Petrović Mila Kovačević Tatjana Miljković Marija Bjelobrk Lazar Velicki |
| author_sort | Milenko Čanković |
| collection | DOAJ |
| description | The aim of the study was to determine major adverse cardiac events (MACE)
related to the percutaneous coronary intervention (PCI) on saphenous vein graft (SVG) with a second-
generation drug eluting stents in patients with previous coronary artery bypass graft (CABG).
The research was conducted as a unicenter retrospective observational study which analyzed consecutive
patients of both genders who had PCI on SVG from January 1, 2016 until June 30, 2019. The
aim was to investigate the occurrence of MACE defined as development of periprocedural myocardial
infarction, acute heart failure in the first 24 hours after PCI, unstable angina after PCI, periprocedural
stroke, contrast induced nephropathy, death, acute/subacute/late stent thrombosis, and target
lesion revascularization. The study included 97 consecutive patients. MACE was recorded in 20.6%
of patients, more often in patients with thrombolysis in myocardial infarction grade flow ≤2. High
thrombus burden (HTB) was detected in 44.3% of patients and it significantly contributed to the
development of MACE. In conclusion, PCI on SVG is a highly challenging procedure, especially in
patients with an acute coronary syndrome. In patients who have HTB recorded in SVG, the usage of
thrombus aspiration and distal protection device can reduce the frequency of no-reflow phenomenon
and consequential MACE. |
| format | Article |
| id | doaj-art-042b5012c1a64d4297fa02c0735e790a |
| institution | Kabale University |
| issn | 0353-9466 1333-9451 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Sestre Milosrdnice University hospital, Institute of Clinical Medical Research |
| record_format | Article |
| series | Acta Clinica Croatica |
| spelling | doaj-art-042b5012c1a64d4297fa02c0735e790a2025-08-20T03:50:06ZengSestre Milosrdnice University hospital, Institute of Clinical Medical ResearchActa Clinica Croatica0353-94661333-94512024-01-0163.3-461161710.20471/acc.2024.63.03-04.20Percutaneous Coronary Intervention on Saphenous Vein Graft in Second Generation Drug Eluting Stent EraMilenko Čanković0Andrej Preveden1Vladimir Ivanović2Aleksandra Milovančev3Milovan Petrović4Mila Kovačević5Tatjana Miljković6Marija Bjelobrk7Lazar Velicki8Faculty of Medicine, University of Novi Sad, Novi Sad, Serbia; Institute of Cardiovascular Diseases Vojvodina, Sremska Kamenica, SerbiaFaculty of Medicine, University of Novi Sad, Novi Sad, Serbia; Institute of Cardiovascular Diseases Vojvodina, Sremska Kamenica, SerbiaFaculty of Medicine, University of Novi Sad, Novi Sad, Serbia; Institute of Cardiovascular Diseases Vojvodina, Sremska Kamenica, SerbiaFaculty of Medicine, University of Novi Sad, Novi Sad, Serbia; Institute of Cardiovascular Diseases Vojvodina, Sremska Kamenica, SerbiaFaculty of Medicine, University of Novi Sad, Novi Sad, Serbia; Institute of Cardiovascular Diseases Vojvodina, Sremska Kamenica, SerbiaFaculty of Medicine, University of Novi Sad, Novi Sad, Serbia; Institute of Cardiovascular Diseases Vojvodina, Sremska Kamenica, SerbiaFaculty of Medicine, University of Novi Sad, Novi Sad, Serbia; Institute of Cardiovascular Diseases Vojvodina, Sremska Kamenica, SerbiaFaculty of Medicine, University of Novi Sad, Novi Sad, Serbia; Institute of Cardiovascular Diseases Vojvodina, Sremska Kamenica, SerbiaFaculty of Medicine, University of Novi Sad, Novi Sad, Serbia; Institute of Cardiovascular Diseases Vojvodina, Sremska Kamenica, SerbiaThe aim of the study was to determine major adverse cardiac events (MACE) related to the percutaneous coronary intervention (PCI) on saphenous vein graft (SVG) with a second- generation drug eluting stents in patients with previous coronary artery bypass graft (CABG). The research was conducted as a unicenter retrospective observational study which analyzed consecutive patients of both genders who had PCI on SVG from January 1, 2016 until June 30, 2019. The aim was to investigate the occurrence of MACE defined as development of periprocedural myocardial infarction, acute heart failure in the first 24 hours after PCI, unstable angina after PCI, periprocedural stroke, contrast induced nephropathy, death, acute/subacute/late stent thrombosis, and target lesion revascularization. The study included 97 consecutive patients. MACE was recorded in 20.6% of patients, more often in patients with thrombolysis in myocardial infarction grade flow ≤2. High thrombus burden (HTB) was detected in 44.3% of patients and it significantly contributed to the development of MACE. In conclusion, PCI on SVG is a highly challenging procedure, especially in patients with an acute coronary syndrome. In patients who have HTB recorded in SVG, the usage of thrombus aspiration and distal protection device can reduce the frequency of no-reflow phenomenon and consequential MACE.https://hrcak.srce.hr/file/481998aphenous vein graftPercutaneous coronary interventionMajor adverse cardiac eventHigh thrombus burden |
| spellingShingle | Milenko Čanković Andrej Preveden Vladimir Ivanović Aleksandra Milovančev Milovan Petrović Mila Kovačević Tatjana Miljković Marija Bjelobrk Lazar Velicki Percutaneous Coronary Intervention on Saphenous Vein Graft in Second Generation Drug Eluting Stent Era Acta Clinica Croatica aphenous vein graft Percutaneous coronary intervention Major adverse cardiac event High thrombus burden |
| title | Percutaneous Coronary Intervention on Saphenous Vein Graft in Second Generation Drug Eluting Stent Era |
| title_full | Percutaneous Coronary Intervention on Saphenous Vein Graft in Second Generation Drug Eluting Stent Era |
| title_fullStr | Percutaneous Coronary Intervention on Saphenous Vein Graft in Second Generation Drug Eluting Stent Era |
| title_full_unstemmed | Percutaneous Coronary Intervention on Saphenous Vein Graft in Second Generation Drug Eluting Stent Era |
| title_short | Percutaneous Coronary Intervention on Saphenous Vein Graft in Second Generation Drug Eluting Stent Era |
| title_sort | percutaneous coronary intervention on saphenous vein graft in second generation drug eluting stent era |
| topic | aphenous vein graft Percutaneous coronary intervention Major adverse cardiac event High thrombus burden |
| url | https://hrcak.srce.hr/file/481998 |
| work_keys_str_mv | AT milenkocankovic percutaneouscoronaryinterventiononsaphenousveingraftinsecondgenerationdrugelutingstentera AT andrejpreveden percutaneouscoronaryinterventiononsaphenousveingraftinsecondgenerationdrugelutingstentera AT vladimirivanovic percutaneouscoronaryinterventiononsaphenousveingraftinsecondgenerationdrugelutingstentera AT aleksandramilovancev percutaneouscoronaryinterventiononsaphenousveingraftinsecondgenerationdrugelutingstentera AT milovanpetrovic percutaneouscoronaryinterventiononsaphenousveingraftinsecondgenerationdrugelutingstentera AT milakovacevic percutaneouscoronaryinterventiononsaphenousveingraftinsecondgenerationdrugelutingstentera AT tatjanamiljkovic percutaneouscoronaryinterventiononsaphenousveingraftinsecondgenerationdrugelutingstentera AT marijabjelobrk percutaneouscoronaryinterventiononsaphenousveingraftinsecondgenerationdrugelutingstentera AT lazarvelicki percutaneouscoronaryinterventiononsaphenousveingraftinsecondgenerationdrugelutingstentera |