Obtaining a mouse model of streptozotocininduced type 1 diabetes mellitus

Objective: to obtain a stable mouse model of type 1 diabetes mellitus (T1DM) using streptozotocin (STZ), which has a toxic effect on pancreatic beta cells.Materials and methods. Experiments were performed on 30 white non-diabetic male mice of the SHK colony, which were injected intraperitoneally wit...

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Bibliographic Details
Main Authors: G. N. Skaletskaya, N. N. Skaletskiy, G. N. Bubentsova, L. A. Kirsanova, Yu. B. Basok, V. I. Sevastianov
Format: Article
Language:Russian
Published: Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov 2024-07-01
Series:Вестник трансплантологии и искусственных органов
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Online Access:https://journal.transpl.ru/vtio/article/view/1763
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