Characteristics and Mechanism of Ammonia Nitrogen Removal by Heterotrophic Nitrification Bacterium <i>Klebsiella pneumoniae</i> LCU1 and Its Application in Wastewater Treatment

In this study, a novel strain exhibiting heterotrophic nitrification was screened; subsequently, the strain was identified as <i>Klebsiella pneumoniae</i> LCU1 using 16S rRNA gene sequencing. The aim of the study was to investigate the effects of external factors on the NH<sub>4<...

Full description

Saved in:
Bibliographic Details
Main Authors: Meng Xu, Lifei Chen, Yizhen Xin, Xiangyu Wang, Zhuoya Wang, Xueqiang Meng, Wenyu Zhang, Haoyang Sun, Yifan Li, Wenzhe Zhang, Peng Wan, Bingshuai Geng, Lusheng Li
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Microorganisms
Subjects:
Online Access:https://www.mdpi.com/2076-2607/13/2/297
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850080171135074304
author Meng Xu
Lifei Chen
Yizhen Xin
Xiangyu Wang
Zhuoya Wang
Xueqiang Meng
Wenyu Zhang
Haoyang Sun
Yifan Li
Wenzhe Zhang
Peng Wan
Bingshuai Geng
Lusheng Li
author_facet Meng Xu
Lifei Chen
Yizhen Xin
Xiangyu Wang
Zhuoya Wang
Xueqiang Meng
Wenyu Zhang
Haoyang Sun
Yifan Li
Wenzhe Zhang
Peng Wan
Bingshuai Geng
Lusheng Li
author_sort Meng Xu
collection DOAJ
description In this study, a novel strain exhibiting heterotrophic nitrification was screened; subsequently, the strain was identified as <i>Klebsiella pneumoniae</i> LCU1 using 16S rRNA gene sequencing. The aim of the study was to investigate the effects of external factors on the NH<sub>4</sub><sup>+</sup>-N removal efficiency of strain LCU1 in order to elucidate the optimal conditions for NH<sub>4</sub><sup>+</sup>-N removal by the strain and improve the removal efficiency. The findings indicated that the NH<sub>4</sub><sup>+</sup>-N removal efficiency of the strain exceeded 80% under optimal conditions (sodium succinate carbon source, C/N ratio of 10, initial pH of 8.0, temperature of 30 °C, and speed of 180 rpm). The genome analysis of strain LCU1 showed that key genes involved in nitrogen metabolism, including <i>nar</i>GHI, <i>nir</i>B, <i>nxr</i>AB, and <i>nas</i>AB, were successfully annotated; <i>hao</i> and <i>amo</i> were absent, but the nitrogen properties analysis determined that the strain had a heterotrophic nitrification ability. After 120 h, the NH<sub>4</sub><sup>+</sup>-N removal efficiency of strain LCU1 was 34.5% at a high NH<sub>4</sub><sup>+</sup>-N concentration of 2000 mg/L. More importantly, the NH<sub>4</sub><sup>+</sup>-N removal efficiency of this strain was above 34.13% at higher Cu<sup>2+</sup>, Mn<sup>2+</sup>, and Zn<sup>2+</sup> ion concentrations. Furthermore, strain LCU1 had the highest NH<sub>4</sub><sup>+</sup>-N removal efficiency of 34.51% for unsterilised (LCU1-OC) aquaculture wastewater. This suggests that with intensive colonisation treatment, the strain has promising application potential in real wastewater treatment.
format Article
id doaj-art-03f0be6a2f8b4895bf8bdb3ab6d696e4
institution DOAJ
issn 2076-2607
language English
publishDate 2025-01-01
publisher MDPI AG
record_format Article
series Microorganisms
spelling doaj-art-03f0be6a2f8b4895bf8bdb3ab6d696e42025-08-20T02:45:00ZengMDPI AGMicroorganisms2076-26072025-01-0113229710.3390/microorganisms13020297Characteristics and Mechanism of Ammonia Nitrogen Removal by Heterotrophic Nitrification Bacterium <i>Klebsiella pneumoniae</i> LCU1 and Its Application in Wastewater TreatmentMeng Xu0Lifei Chen1Yizhen Xin2Xiangyu Wang3Zhuoya Wang4Xueqiang Meng5Wenyu Zhang6Haoyang Sun7Yifan Li8Wenzhe Zhang9Peng Wan10Bingshuai Geng11Lusheng Li12School of Agricultural Science and Biology, Liaocheng University, Liaocheng 252000, ChinaSchool of Agricultural Science and Biology, Liaocheng University, Liaocheng 252000, ChinaSchool of Agricultural Science and Biology, Liaocheng University, Liaocheng 252000, ChinaSchool of Agricultural Science and Biology, Liaocheng University, Liaocheng 252000, ChinaSchool of Agricultural Science and Biology, Liaocheng University, Liaocheng 252000, ChinaSchool of Agricultural Science and Biology, Liaocheng University, Liaocheng 252000, ChinaSchool of Agricultural Science and Biology, Liaocheng University, Liaocheng 252000, ChinaSchool of Agricultural Science and Biology, Liaocheng University, Liaocheng 252000, ChinaSchool of Agricultural Science and Biology, Liaocheng University, Liaocheng 252000, ChinaSchool of Agricultural Science and Biology, Liaocheng University, Liaocheng 252000, ChinaSchool of Agricultural Science and Biology, Liaocheng University, Liaocheng 252000, ChinaSchool of Agricultural Science and Biology, Liaocheng University, Liaocheng 252000, ChinaSchool of Agricultural Science and Biology, Liaocheng University, Liaocheng 252000, ChinaIn this study, a novel strain exhibiting heterotrophic nitrification was screened; subsequently, the strain was identified as <i>Klebsiella pneumoniae</i> LCU1 using 16S rRNA gene sequencing. The aim of the study was to investigate the effects of external factors on the NH<sub>4</sub><sup>+</sup>-N removal efficiency of strain LCU1 in order to elucidate the optimal conditions for NH<sub>4</sub><sup>+</sup>-N removal by the strain and improve the removal efficiency. The findings indicated that the NH<sub>4</sub><sup>+</sup>-N removal efficiency of the strain exceeded 80% under optimal conditions (sodium succinate carbon source, C/N ratio of 10, initial pH of 8.0, temperature of 30 °C, and speed of 180 rpm). The genome analysis of strain LCU1 showed that key genes involved in nitrogen metabolism, including <i>nar</i>GHI, <i>nir</i>B, <i>nxr</i>AB, and <i>nas</i>AB, were successfully annotated; <i>hao</i> and <i>amo</i> were absent, but the nitrogen properties analysis determined that the strain had a heterotrophic nitrification ability. After 120 h, the NH<sub>4</sub><sup>+</sup>-N removal efficiency of strain LCU1 was 34.5% at a high NH<sub>4</sub><sup>+</sup>-N concentration of 2000 mg/L. More importantly, the NH<sub>4</sub><sup>+</sup>-N removal efficiency of this strain was above 34.13% at higher Cu<sup>2+</sup>, Mn<sup>2+</sup>, and Zn<sup>2+</sup> ion concentrations. Furthermore, strain LCU1 had the highest NH<sub>4</sub><sup>+</sup>-N removal efficiency of 34.51% for unsterilised (LCU1-OC) aquaculture wastewater. This suggests that with intensive colonisation treatment, the strain has promising application potential in real wastewater treatment.https://www.mdpi.com/2076-2607/13/2/297<i>Klebsiella pneumoniae</i>heterotrophic nitrificationwastewater treatment
spellingShingle Meng Xu
Lifei Chen
Yizhen Xin
Xiangyu Wang
Zhuoya Wang
Xueqiang Meng
Wenyu Zhang
Haoyang Sun
Yifan Li
Wenzhe Zhang
Peng Wan
Bingshuai Geng
Lusheng Li
Characteristics and Mechanism of Ammonia Nitrogen Removal by Heterotrophic Nitrification Bacterium <i>Klebsiella pneumoniae</i> LCU1 and Its Application in Wastewater Treatment
Microorganisms
<i>Klebsiella pneumoniae</i>
heterotrophic nitrification
wastewater treatment
title Characteristics and Mechanism of Ammonia Nitrogen Removal by Heterotrophic Nitrification Bacterium <i>Klebsiella pneumoniae</i> LCU1 and Its Application in Wastewater Treatment
title_full Characteristics and Mechanism of Ammonia Nitrogen Removal by Heterotrophic Nitrification Bacterium <i>Klebsiella pneumoniae</i> LCU1 and Its Application in Wastewater Treatment
title_fullStr Characteristics and Mechanism of Ammonia Nitrogen Removal by Heterotrophic Nitrification Bacterium <i>Klebsiella pneumoniae</i> LCU1 and Its Application in Wastewater Treatment
title_full_unstemmed Characteristics and Mechanism of Ammonia Nitrogen Removal by Heterotrophic Nitrification Bacterium <i>Klebsiella pneumoniae</i> LCU1 and Its Application in Wastewater Treatment
title_short Characteristics and Mechanism of Ammonia Nitrogen Removal by Heterotrophic Nitrification Bacterium <i>Klebsiella pneumoniae</i> LCU1 and Its Application in Wastewater Treatment
title_sort characteristics and mechanism of ammonia nitrogen removal by heterotrophic nitrification bacterium i klebsiella pneumoniae i lcu1 and its application in wastewater treatment
topic <i>Klebsiella pneumoniae</i>
heterotrophic nitrification
wastewater treatment
url https://www.mdpi.com/2076-2607/13/2/297
work_keys_str_mv AT mengxu characteristicsandmechanismofammonianitrogenremovalbyheterotrophicnitrificationbacteriumiklebsiellapneumoniaeilcu1anditsapplicationinwastewatertreatment
AT lifeichen characteristicsandmechanismofammonianitrogenremovalbyheterotrophicnitrificationbacteriumiklebsiellapneumoniaeilcu1anditsapplicationinwastewatertreatment
AT yizhenxin characteristicsandmechanismofammonianitrogenremovalbyheterotrophicnitrificationbacteriumiklebsiellapneumoniaeilcu1anditsapplicationinwastewatertreatment
AT xiangyuwang characteristicsandmechanismofammonianitrogenremovalbyheterotrophicnitrificationbacteriumiklebsiellapneumoniaeilcu1anditsapplicationinwastewatertreatment
AT zhuoyawang characteristicsandmechanismofammonianitrogenremovalbyheterotrophicnitrificationbacteriumiklebsiellapneumoniaeilcu1anditsapplicationinwastewatertreatment
AT xueqiangmeng characteristicsandmechanismofammonianitrogenremovalbyheterotrophicnitrificationbacteriumiklebsiellapneumoniaeilcu1anditsapplicationinwastewatertreatment
AT wenyuzhang characteristicsandmechanismofammonianitrogenremovalbyheterotrophicnitrificationbacteriumiklebsiellapneumoniaeilcu1anditsapplicationinwastewatertreatment
AT haoyangsun characteristicsandmechanismofammonianitrogenremovalbyheterotrophicnitrificationbacteriumiklebsiellapneumoniaeilcu1anditsapplicationinwastewatertreatment
AT yifanli characteristicsandmechanismofammonianitrogenremovalbyheterotrophicnitrificationbacteriumiklebsiellapneumoniaeilcu1anditsapplicationinwastewatertreatment
AT wenzhezhang characteristicsandmechanismofammonianitrogenremovalbyheterotrophicnitrificationbacteriumiklebsiellapneumoniaeilcu1anditsapplicationinwastewatertreatment
AT pengwan characteristicsandmechanismofammonianitrogenremovalbyheterotrophicnitrificationbacteriumiklebsiellapneumoniaeilcu1anditsapplicationinwastewatertreatment
AT bingshuaigeng characteristicsandmechanismofammonianitrogenremovalbyheterotrophicnitrificationbacteriumiklebsiellapneumoniaeilcu1anditsapplicationinwastewatertreatment
AT lushengli characteristicsandmechanismofammonianitrogenremovalbyheterotrophicnitrificationbacteriumiklebsiellapneumoniaeilcu1anditsapplicationinwastewatertreatment