Brain reserve in hepatic encephalopathy: Pathways of damage and preventive strategies through lifestyle and therapeutic interventions

Brain reserve is an important concept to understand the variability of damage associated with brain-related diseases and includes the adaptation of cognitive processes to preserve brain function. A good cognitive reserve might delay the onset of clinical manifestations of neurodegenerative diseases...

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Main Authors: Jacqueline Cordova-Gallardo, Andres Manuel Vargas-Beltran, Samantha Melanie Armendariz-Pineda, Jesus Ruiz-Manriquez, Javier Ampuero, Aldo Torre
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Annals of Hepatology
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Online Access:http://www.sciencedirect.com/science/article/pii/S1665268124005234
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author Jacqueline Cordova-Gallardo
Andres Manuel Vargas-Beltran
Samantha Melanie Armendariz-Pineda
Jesus Ruiz-Manriquez
Javier Ampuero
Aldo Torre
author_facet Jacqueline Cordova-Gallardo
Andres Manuel Vargas-Beltran
Samantha Melanie Armendariz-Pineda
Jesus Ruiz-Manriquez
Javier Ampuero
Aldo Torre
author_sort Jacqueline Cordova-Gallardo
collection DOAJ
description Brain reserve is an important concept to understand the variability of damage associated with brain-related diseases and includes the adaptation of cognitive processes to preserve brain function. A good cognitive reserve might delay the onset of clinical manifestations of neurodegenerative diseases as well as hepatic encephalopathy, improving the quality of life in patients with chronic liver diseases. By stimulating activities and maintaining overall health, individuals may be able to enhance their brain's resilience to age-related changes and pathology. This review aims to collect all the data available on the role of brain reserve in hepatic encephalopathy development, and the potential effect of a good brain reserve in slowing down hepatic encephalopathy progression and frequency.
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issn 1665-2681
language English
publishDate 2025-01-01
publisher Elsevier
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series Annals of Hepatology
spelling doaj-art-03eeb224bf2c404e845b7066d8edccd62025-08-20T02:01:51ZengElsevierAnnals of Hepatology1665-26812025-01-0130110174010.1016/j.aohep.2024.101740Brain reserve in hepatic encephalopathy: Pathways of damage and preventive strategies through lifestyle and therapeutic interventionsJacqueline Cordova-Gallardo0Andres Manuel Vargas-Beltran1Samantha Melanie Armendariz-Pineda2Jesus Ruiz-Manriquez3Javier Ampuero4Aldo Torre5Department of Gastroenterology, Service of Internal Medicine, General Hospital “Dr. Manuel Gea González”, 14080 Mexico City, Mexico; Faculty of Medicine. National Autonomous University of Mexico, 04360 Mexico City, MexicoDepartment of Gastroenterology, Service of Internal Medicine, General Hospital “Dr. Manuel Gea González”, 14080 Mexico City, Mexico; Faculty of Medicine, Meritorious Autonomous University of Puebla, 72420 Puebla, MexicoDepartment of Gastroenterology, Service of Internal Medicine, General Hospital “Dr. Manuel Gea González”, 14080 Mexico City, Mexico; Faculty of Medicine. National Autonomous University of Mexico, 04360 Mexico City, MexicoDepartment of Gastroenterology, Service of Internal Medicine, General Hospital “Dr. Manuel Gea González”, 14080 Mexico City, MexicoUnit for the Clinical Management of Digestive Diseases, Virgen del Rocío University Hospital, Institute of Biomedicine of Sevilla (IBIS) University of Sevilla, 41013 Sevilla, SpainMetabolic Unit. National Institute of Medical Sciences and Nutrition Salvador Zubiran, 14080 Mexico City, Mexico; Guest Researcher Hepatology, General Hospital of Mexico, Mexico City, Mexico; Gastroenterology Department, ABC Hospital, Mexico City, Mexico; Corresponding author.Brain reserve is an important concept to understand the variability of damage associated with brain-related diseases and includes the adaptation of cognitive processes to preserve brain function. A good cognitive reserve might delay the onset of clinical manifestations of neurodegenerative diseases as well as hepatic encephalopathy, improving the quality of life in patients with chronic liver diseases. By stimulating activities and maintaining overall health, individuals may be able to enhance their brain's resilience to age-related changes and pathology. This review aims to collect all the data available on the role of brain reserve in hepatic encephalopathy development, and the potential effect of a good brain reserve in slowing down hepatic encephalopathy progression and frequency.http://www.sciencedirect.com/science/article/pii/S1665268124005234Brain reserveHepatic encephalopathyCognitive impairmentManagementLifestyle
spellingShingle Jacqueline Cordova-Gallardo
Andres Manuel Vargas-Beltran
Samantha Melanie Armendariz-Pineda
Jesus Ruiz-Manriquez
Javier Ampuero
Aldo Torre
Brain reserve in hepatic encephalopathy: Pathways of damage and preventive strategies through lifestyle and therapeutic interventions
Annals of Hepatology
Brain reserve
Hepatic encephalopathy
Cognitive impairment
Management
Lifestyle
title Brain reserve in hepatic encephalopathy: Pathways of damage and preventive strategies through lifestyle and therapeutic interventions
title_full Brain reserve in hepatic encephalopathy: Pathways of damage and preventive strategies through lifestyle and therapeutic interventions
title_fullStr Brain reserve in hepatic encephalopathy: Pathways of damage and preventive strategies through lifestyle and therapeutic interventions
title_full_unstemmed Brain reserve in hepatic encephalopathy: Pathways of damage and preventive strategies through lifestyle and therapeutic interventions
title_short Brain reserve in hepatic encephalopathy: Pathways of damage and preventive strategies through lifestyle and therapeutic interventions
title_sort brain reserve in hepatic encephalopathy pathways of damage and preventive strategies through lifestyle and therapeutic interventions
topic Brain reserve
Hepatic encephalopathy
Cognitive impairment
Management
Lifestyle
url http://www.sciencedirect.com/science/article/pii/S1665268124005234
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