Peptide bonds strike back
Recent advances in protein design and protein structure prediction have questioned whether experimental structural biology still has a role to play in research today. The article by Panjikar and Weiss [(2025). IUCrJ, 12, 307–321] partially answers this question and alludes to a role still to be play...
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| Format: | Article |
| Language: | English |
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International Union of Crystallography
2025-05-01
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| Series: | IUCrJ |
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| Online Access: | https://journals.iucr.org/paper?S2052252525003604 |
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| Summary: | Recent advances in protein design and protein structure prediction have questioned whether experimental structural biology still has a role to play in research today. The article by Panjikar and Weiss [(2025). IUCrJ, 12, 307–321] partially answers this question and alludes to a role still to be played by structural biology. Several properties of peptide bonds, likely important for function, are described that are absent in protein design and predicted protein structures, and that have largely been overlooked by the structural biology community. |
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| ISSN: | 2052-2525 |