Comparative analysis of lumbar spinal decompression: Propensity-matched evaluation of multilevel vs. single-level decompression for spinal stenosis

Introduction: Lumbar spinal stenosis results in pain in the buttocks and/or legs due to reduced space in the spinal canal. MRI findings indicate that approximately 40 % of clinically diagnosed patients have multilevel stenosis. For patients with severe symptoms requiring spinal decompression, surgeo...

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Main Authors: Mikkel Ø. Andersen, Stefan Hummel, Casper Friis Pedersen, Leah Y. Carreon, Andreas K. Andresen
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Brain and Spine
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Online Access:http://www.sciencedirect.com/science/article/pii/S2772529425001468
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author Mikkel Ø. Andersen
Stefan Hummel
Casper Friis Pedersen
Leah Y. Carreon
Andreas K. Andresen
author_facet Mikkel Ø. Andersen
Stefan Hummel
Casper Friis Pedersen
Leah Y. Carreon
Andreas K. Andresen
author_sort Mikkel Ø. Andersen
collection DOAJ
description Introduction: Lumbar spinal stenosis results in pain in the buttocks and/or legs due to reduced space in the spinal canal. MRI findings indicate that approximately 40 % of clinically diagnosed patients have multilevel stenosis. For patients with severe symptoms requiring spinal decompression, surgeons must decide the optimal number of levels to decompress. However, the benefits of operating on multiple stenotic levels remain uncertain, as limited research has explored this issue. Research question: Do patients with multi-level lumbar stenosis experience less benefit from spinal decompression at the stenotic levels compared to patients with single-level lumbar stenosis? Material and methods: In this study, all patients who underwent spinal decompression due to spinal stenosis between June 2010 and December 2024 were included. Pre- and postoperative data collected included demographic information, back and leg pain levels, health-related quality of life, disability, and the duration of back and leg pain before surgery. Patients were categorized into four groups based on the number of decompressed levels. To ensure comparability between the groups, propensity-score matching was conducted in a 1:1 ratio. Results: Of 3307 patients undergoing spinal decompression, we formed four matched cohorts, balanced on preoperative factors. With the exception of a significant increasing number of dural tears proportional to the number of decompressed levels, there were no differences in complication rates or patient-reported satisfaction with the outcome. Discussion and conclusion: We found no significant difference in patient satisfaction and health-related quality of life in patients related to the number of levels decompressed due to symptomatic spinal stenosis.
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spelling doaj-art-03ddc1d974f64118a52e6fcd71a3e79f2025-08-20T03:24:56ZengElsevierBrain and Spine2772-52942025-01-01510432710.1016/j.bas.2025.104327Comparative analysis of lumbar spinal decompression: Propensity-matched evaluation of multilevel vs. single-level decompression for spinal stenosisMikkel Ø. Andersen0Stefan Hummel1Casper Friis Pedersen2Leah Y. Carreon3Andreas K. Andresen4Center for Spine Surgery and Research, Lillebaelt Hospital, Kolding, Denmark; Institute of Regional Health Research, University of Southern Denmark, Campusvej 55, DK-5230, Odense M, DenmarkCenter for Spine Surgery and Research, Lillebaelt Hospital, Kolding, DenmarkCenter for Spine Surgery and Research, Lillebaelt Hospital, Kolding, DenmarkCenter for Spine Surgery and Research, Lillebaelt Hospital, Kolding, Denmark; Institute of Regional Health Research, University of Southern Denmark, Campusvej 55, DK-5230, Odense M, DenmarkCenter for Spine Surgery and Research, Lillebaelt Hospital, Kolding, Denmark; Institute of Regional Health Research, University of Southern Denmark, Campusvej 55, DK-5230, Odense M, Denmark; Corresponding author. Center for Spine Surgery and Research, Lillebaelt Hospital, Sygehusvej 24, DK- 6000, Denmark.Introduction: Lumbar spinal stenosis results in pain in the buttocks and/or legs due to reduced space in the spinal canal. MRI findings indicate that approximately 40 % of clinically diagnosed patients have multilevel stenosis. For patients with severe symptoms requiring spinal decompression, surgeons must decide the optimal number of levels to decompress. However, the benefits of operating on multiple stenotic levels remain uncertain, as limited research has explored this issue. Research question: Do patients with multi-level lumbar stenosis experience less benefit from spinal decompression at the stenotic levels compared to patients with single-level lumbar stenosis? Material and methods: In this study, all patients who underwent spinal decompression due to spinal stenosis between June 2010 and December 2024 were included. Pre- and postoperative data collected included demographic information, back and leg pain levels, health-related quality of life, disability, and the duration of back and leg pain before surgery. Patients were categorized into four groups based on the number of decompressed levels. To ensure comparability between the groups, propensity-score matching was conducted in a 1:1 ratio. Results: Of 3307 patients undergoing spinal decompression, we formed four matched cohorts, balanced on preoperative factors. With the exception of a significant increasing number of dural tears proportional to the number of decompressed levels, there were no differences in complication rates or patient-reported satisfaction with the outcome. Discussion and conclusion: We found no significant difference in patient satisfaction and health-related quality of life in patients related to the number of levels decompressed due to symptomatic spinal stenosis.http://www.sciencedirect.com/science/article/pii/S2772529425001468Lumbar spinal stenosisNeurogenic claudicationSpinal decompressionPropensity matchingPatient satisfaction
spellingShingle Mikkel Ø. Andersen
Stefan Hummel
Casper Friis Pedersen
Leah Y. Carreon
Andreas K. Andresen
Comparative analysis of lumbar spinal decompression: Propensity-matched evaluation of multilevel vs. single-level decompression for spinal stenosis
Brain and Spine
Lumbar spinal stenosis
Neurogenic claudication
Spinal decompression
Propensity matching
Patient satisfaction
title Comparative analysis of lumbar spinal decompression: Propensity-matched evaluation of multilevel vs. single-level decompression for spinal stenosis
title_full Comparative analysis of lumbar spinal decompression: Propensity-matched evaluation of multilevel vs. single-level decompression for spinal stenosis
title_fullStr Comparative analysis of lumbar spinal decompression: Propensity-matched evaluation of multilevel vs. single-level decompression for spinal stenosis
title_full_unstemmed Comparative analysis of lumbar spinal decompression: Propensity-matched evaluation of multilevel vs. single-level decompression for spinal stenosis
title_short Comparative analysis of lumbar spinal decompression: Propensity-matched evaluation of multilevel vs. single-level decompression for spinal stenosis
title_sort comparative analysis of lumbar spinal decompression propensity matched evaluation of multilevel vs single level decompression for spinal stenosis
topic Lumbar spinal stenosis
Neurogenic claudication
Spinal decompression
Propensity matching
Patient satisfaction
url http://www.sciencedirect.com/science/article/pii/S2772529425001468
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