Plasma extracellular vesicle-associated miR-512-3p modulates angiogenesis in pediatric Moyamoya disease by targeting ARHGEF3.

Plasma extracellular vesicle-associated miR-512-3p modulates angiogenesis in pediatric Moyamoya disease by targeting ARHGEF3.

Abstract Moyamoya disease (MMD) is a chronic cerebrovascular disorder and a leading cause of pediatric stroke. Extracellular vesicles (EVs) carrying microRNAs (miRNAs) play a pivotal role in intercellular communication within cerebrovascular diseases. This study aimed to identify specific miRNAs wit...

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Bibliographic Details
Main Authors: Eun Jung Koh, Seung Ah Choi, Youn Joo Moon, Heeyoung Lee, Ji Hoon Phi, Seung-Ki Kim
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Moyamoya disease
Extracellular vesicles
Endothelial colony-forming cells
MiR-512-3p
ARHGEF3
Online Access:https://doi.org/10.1038/s41598-025-08796-4
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