Sulfunic Acid Modifired MCM-41 Mesoporous Silica as an Efficient Nano-Catalyst for Synthesis of amides and lactams from Oximes Via Beckman Rearrangement
Mesoporous MCM-41 silicas anchored with sulfonic acid (–SO3H) groups (denoted MSN-SA) via postsynthesis modification are very effective for the Beckman rearrangement. A simple and convenient procedure for conversion of a variety oximes to their corresponding amides and lactams has been developed. Th...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
University of Tehran
2016-07-01
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| Series: | Journal of Sciences, Islamic Republic of Iran |
| Subjects: | |
| Online Access: | https://jsciences.ut.ac.ir/article_57655_ec5991b3e3720ef49f4fe2bf54f36815.pdf |
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| Summary: | Mesoporous MCM-41 silicas anchored with sulfonic acid (–SO3H) groups (denoted MSN-SA) via postsynthesis modification are very effective for the Beckman rearrangement. A simple and convenient procedure for conversion of a variety oximes to their corresponding amides and lactams has been developed. The reaction was carried out in the presence of MSN-SA as the catalyst. The best results for conversion of oximes to amides and lactams were obtained in the presence of MSN-SA and solvent free condition at 110 ºC. Excellent yields were obtained from oximes with electron-donating and electron-withdrawing groups. The system also worked well with polynuclear aromatic, heterocyclic and aliphatic oximes. |
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| ISSN: | 1016-1104 2345-6914 |