RATIONAL APPROACH TO A COMBINATION THERAPY OF FOCAL EPILEPSY
Abstract: the article presents a discussion of the problem of rational polytherapy (RPT). RPT has become one of the main strategies of modern epilepsy treatment. Early using of the RPT is a tactic of choice for patients with high risk for pharmacoresistant epilepsy (EDF) and for patients with risk o...
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| Format: | Article |
| Language: | Russian |
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IRBIS LLC
2016-05-01
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| Series: | Эпилепсия и пароксизмальные состояния |
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| Online Access: | https://www.epilepsia.su/jour/article/view/79 |
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| _version_ | 1849696073338060800 |
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| author | I. G. Rudakova |
| author_facet | I. G. Rudakova |
| author_sort | I. G. Rudakova |
| collection | DOAJ |
| description | Abstract: the article presents a discussion of the problem of rational polytherapy (RPT). RPT has become one of the main strategies of modern epilepsy treatment. Early using of the RPT is a tactic of choice for patients with high risk for pharmacoresistant epilepsy (EDF) and for patients with risk of problems that can occur while switching to alternative monotherapy. For early RPT a seizure control can be achieved more quick. That reduces the risks associated with seizures for patients with severe epilepsy. AEDs choice for the RPT should be based on the prevention of the pharmacodynamic and pharmacokinetic side effects. But efficacy data of AEDs in clinical practice should be taking into account. |
| format | Article |
| id | doaj-art-03c0609d505a4808be24eb2a4cae643a |
| institution | DOAJ |
| issn | 2077-8333 2311-4088 |
| language | Russian |
| publishDate | 2016-05-01 |
| publisher | IRBIS LLC |
| record_format | Article |
| series | Эпилепсия и пароксизмальные состояния |
| spelling | doaj-art-03c0609d505a4808be24eb2a4cae643a2025-08-20T03:19:34ZrusIRBIS LLCЭпилепсия и пароксизмальные состояния2077-83332311-40882016-05-0164626678RATIONAL APPROACH TO A COMBINATION THERAPY OF FOCAL EPILEPSYI. G. Rudakova0Moscows regional research clinical institute n.a. M.F. VladimirskiyAbstract: the article presents a discussion of the problem of rational polytherapy (RPT). RPT has become one of the main strategies of modern epilepsy treatment. Early using of the RPT is a tactic of choice for patients with high risk for pharmacoresistant epilepsy (EDF) and for patients with risk of problems that can occur while switching to alternative monotherapy. For early RPT a seizure control can be achieved more quick. That reduces the risks associated with seizures for patients with severe epilepsy. AEDs choice for the RPT should be based on the prevention of the pharmacodynamic and pharmacokinetic side effects. But efficacy data of AEDs in clinical practice should be taking into account.https://www.epilepsia.su/jour/article/view/79epilepsydrug resistantrational polytherapyearly polytherapy |
| spellingShingle | I. G. Rudakova RATIONAL APPROACH TO A COMBINATION THERAPY OF FOCAL EPILEPSY Эпилепсия и пароксизмальные состояния epilepsy drug resistant rational polytherapy early polytherapy |
| title | RATIONAL APPROACH TO A COMBINATION THERAPY OF FOCAL EPILEPSY |
| title_full | RATIONAL APPROACH TO A COMBINATION THERAPY OF FOCAL EPILEPSY |
| title_fullStr | RATIONAL APPROACH TO A COMBINATION THERAPY OF FOCAL EPILEPSY |
| title_full_unstemmed | RATIONAL APPROACH TO A COMBINATION THERAPY OF FOCAL EPILEPSY |
| title_short | RATIONAL APPROACH TO A COMBINATION THERAPY OF FOCAL EPILEPSY |
| title_sort | rational approach to a combination therapy of focal epilepsy |
| topic | epilepsy drug resistant rational polytherapy early polytherapy |
| url | https://www.epilepsia.su/jour/article/view/79 |
| work_keys_str_mv | AT igrudakova rationalapproachtoacombinationtherapyoffocalepilepsy |