RATIONAL APPROACH TO A COMBINATION THERAPY OF FOCAL EPILEPSY
Abstract: the article presents a discussion of the problem of rational polytherapy (RPT). RPT has become one of the main strategies of modern epilepsy treatment. Early using of the RPT is a tactic of choice for patients with high risk for pharmacoresistant epilepsy (EDF) and for patients with risk o...
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| Main Author: | |
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| Format: | Article |
| Language: | Russian |
| Published: |
IRBIS LLC
2016-05-01
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| Series: | Эпилепсия и пароксизмальные состояния |
| Subjects: | |
| Online Access: | https://www.epilepsia.su/jour/article/view/79 |
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| Summary: | Abstract: the article presents a discussion of the problem of rational polytherapy (RPT). RPT has become one of the main strategies of modern epilepsy treatment. Early using of the RPT is a tactic of choice for patients with high risk for pharmacoresistant epilepsy (EDF) and for patients with risk of problems that can occur while switching to alternative monotherapy. For early RPT a seizure control can be achieved more quick. That reduces the risks associated with seizures for patients with severe epilepsy. AEDs choice for the RPT should be based on the prevention of the pharmacodynamic and pharmacokinetic side effects. But efficacy data of AEDs in clinical practice should be taking into account. |
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| ISSN: | 2077-8333 2311-4088 |