Histology Structure of Lymph and Uterus of White Rat (Rattus norvegicus) Given with Nanas Bongsai (Ananas comosus var. microstachys L.)

Nanas Bongsai (Ananas comosus var. microstachys L.) is an amazing herb which is used in traditional medicine by local people of Muara Lembu district as a potion to reduce pain while menstruation period for a women. The present work was designed to investigate its probable side effects on the histopa...

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Main Authors: Fitmawati Fitmawati, Agus Saputra, Yohanes Yohanes, Hilwan Yuda Teruna, Dimas Pramita Nugraha, Yulis Hamidi
Format: Article
Language:English
Published: Universitas Negeri Semarang 2018-04-01
Series:Biosaintifika: Journal of Biology & Biology Education
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Online Access:https://journal.unnes.ac.id/nju/index.php/biosaintifika/article/view/13596
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author Fitmawati Fitmawati
Agus Saputra
Yohanes Yohanes
Hilwan Yuda Teruna
Dimas Pramita Nugraha
Yulis Hamidi
author_facet Fitmawati Fitmawati
Agus Saputra
Yohanes Yohanes
Hilwan Yuda Teruna
Dimas Pramita Nugraha
Yulis Hamidi
author_sort Fitmawati Fitmawati
collection DOAJ
description Nanas Bongsai (Ananas comosus var. microstachys L.) is an amazing herb which is used in traditional medicine by local people of Muara Lembu district as a potion to reduce pain while menstruation period for a women. The present work was designed to investigate its probable side effects on the histopathologic changes in limph and uterus tissues after treated with A. comosus var. microstachys L extract in female white rats. This is an experimental research consisted of five treatments and three repetitions. Treatment composed of two controls (P0 and P+) and given Nanas Bongsai extract with three different dosages. Histology result of lymph show that all treatments given with Nanas Bongsai with three different dosages have different diameter average of white pulp and there is no significant changes with normal control. While observation towards histology structure of endometrium thickness with dosage P1, dosage P2, dosage P3 is 206.333±33.486; 215.667±33.486; 197.667±60.871 respectively. The most thin endometrium layer found in treatment with dosage P3 compared to control P0. From this study showed that there is no toxic effect on uterus and lymph function of of Nanas Bonsai (A. comosus var. microstachys L.) at different doses, so the plant is secure for consumption by the community.
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issn 2085-191X
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publishDate 2018-04-01
publisher Universitas Negeri Semarang
record_format Article
series Biosaintifika: Journal of Biology & Biology Education
spelling doaj-art-03bd25571ecd4d94be648aa1bba3e4a52025-08-20T03:54:14ZengUniversitas Negeri SemarangBiosaintifika: Journal of Biology & Biology Education2085-191X2338-76102018-04-0110122322810.15294/biosaintifika.v10i1.135967380Histology Structure of Lymph and Uterus of White Rat (Rattus norvegicus) Given with Nanas Bongsai (Ananas comosus var. microstachys L.)Fitmawati Fitmawati0Agus Saputra1Yohanes Yohanes2Hilwan Yuda Teruna3Dimas Pramita Nugraha4Yulis Hamidi5Department of Biology, Faculty of Mathematics and Natural Sciences, Universitas Riau KampusDepartment of Biology, Faculty of Mathematics and Natural Sciences, Universitas Riau KampusPublic Health Official, Riau ProvinceDepartment of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas RiauDepartment of Medical, Faculty of Mendical, Universitas RiauDepartment of Medical, Faculty of Mendical, Universitas RiauNanas Bongsai (Ananas comosus var. microstachys L.) is an amazing herb which is used in traditional medicine by local people of Muara Lembu district as a potion to reduce pain while menstruation period for a women. The present work was designed to investigate its probable side effects on the histopathologic changes in limph and uterus tissues after treated with A. comosus var. microstachys L extract in female white rats. This is an experimental research consisted of five treatments and three repetitions. Treatment composed of two controls (P0 and P+) and given Nanas Bongsai extract with three different dosages. Histology result of lymph show that all treatments given with Nanas Bongsai with three different dosages have different diameter average of white pulp and there is no significant changes with normal control. While observation towards histology structure of endometrium thickness with dosage P1, dosage P2, dosage P3 is 206.333±33.486; 215.667±33.486; 197.667±60.871 respectively. The most thin endometrium layer found in treatment with dosage P3 compared to control P0. From this study showed that there is no toxic effect on uterus and lymph function of of Nanas Bonsai (A. comosus var. microstachys L.) at different doses, so the plant is secure for consumption by the community.https://journal.unnes.ac.id/nju/index.php/biosaintifika/article/view/13596nanas bongsai (ananas comosus var. microstachys l.)white rat (rattus norvegicus)lymphuterus
spellingShingle Fitmawati Fitmawati
Agus Saputra
Yohanes Yohanes
Hilwan Yuda Teruna
Dimas Pramita Nugraha
Yulis Hamidi
Histology Structure of Lymph and Uterus of White Rat (Rattus norvegicus) Given with Nanas Bongsai (Ananas comosus var. microstachys L.)
Biosaintifika: Journal of Biology & Biology Education
nanas bongsai (ananas comosus var. microstachys l.)
white rat (rattus norvegicus)
lymph
uterus
title Histology Structure of Lymph and Uterus of White Rat (Rattus norvegicus) Given with Nanas Bongsai (Ananas comosus var. microstachys L.)
title_full Histology Structure of Lymph and Uterus of White Rat (Rattus norvegicus) Given with Nanas Bongsai (Ananas comosus var. microstachys L.)
title_fullStr Histology Structure of Lymph and Uterus of White Rat (Rattus norvegicus) Given with Nanas Bongsai (Ananas comosus var. microstachys L.)
title_full_unstemmed Histology Structure of Lymph and Uterus of White Rat (Rattus norvegicus) Given with Nanas Bongsai (Ananas comosus var. microstachys L.)
title_short Histology Structure of Lymph and Uterus of White Rat (Rattus norvegicus) Given with Nanas Bongsai (Ananas comosus var. microstachys L.)
title_sort histology structure of lymph and uterus of white rat rattus norvegicus given with nanas bongsai ananas comosus var microstachys l
topic nanas bongsai (ananas comosus var. microstachys l.)
white rat (rattus norvegicus)
lymph
uterus
url https://journal.unnes.ac.id/nju/index.php/biosaintifika/article/view/13596
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AT hilwanyudateruna histologystructureoflymphanduterusofwhiteratrattusnorvegicusgivenwithnanasbongsaiananascomosusvarmicrostachysl
AT dimaspramitanugraha histologystructureoflymphanduterusofwhiteratrattusnorvegicusgivenwithnanasbongsaiananascomosusvarmicrostachysl
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