Two new Loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and german study groups.

Two new Loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and german study groups.

Meta-analyses of population-based genome-wide association studies (GWAS) in adults have recently led to the detection of new genetic loci for obesity. Here we aimed to discover additional obesity loci in extremely obese children and adolescents. We also investigated if these results generalize by es...

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Main Authors: André Scherag, Christian Dina, Anke Hinney, Vincent Vatin, Susann Scherag, Carla I G Vogel, Timo D Müller, Harald Grallert, H-Erich Wichmann, Beverley Balkau, Barbara Heude, Marjo-Riitta Jarvelin, Anna-Liisa Hartikainen, Claire Levy-Marchal, Jacques Weill, Jérôme Delplanque, Antje Körner, Wieland Kiess, Peter Kovacs, Nigel W Rayner, Inga Prokopenko, Mark I McCarthy, Helmut Schäfer, Ivonne Jarick, Heiner Boeing, Eva Fisher, Thomas Reinehr, Joachim Heinrich, Peter Rzehak, Dietrich Berdel, Michael Borte, Heike Biebermann, Heiko Krude, Dieter Rosskopf, Christian Rimmbach, Winfried Rief, Tobias Fromme, Martin Klingenspor, Annette Schürmann, Nadja Schulz, Markus M Nöthen, Thomas W Mühleisen, Raimund Erbel, Karl-Heinz Jöckel, Susanne Moebus, Tanja Boes, Thomas Illig, Philippe Froguel, Johannes Hebebrand, David Meyre
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-04-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1000916&type=printable
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