Torsades de Pointes due to Excessive Marijuana Use in a Susceptible Patient
There are several recent reports of tetrahydrocannabinol vaping-related sudden cardiac arrest, and the mechanisms are unclear. We report a unique case of a 19-year-old female who suffered documented prolonged QTc leading to Torsades de pointes and cardiac arrest in the setting of frequent marijuana...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2021-01-01
|
| Series: | Case Reports in Cardiology |
| Online Access: | http://dx.doi.org/10.1155/2021/6621496 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832560642399141888 |
|---|---|
| author | Vivek D. Shah Adeba Mohammad Shuktika Nandkeolyar Liset Stoletniy Tahmeed Contractor |
| author_facet | Vivek D. Shah Adeba Mohammad Shuktika Nandkeolyar Liset Stoletniy Tahmeed Contractor |
| author_sort | Vivek D. Shah |
| collection | DOAJ |
| description | There are several recent reports of tetrahydrocannabinol vaping-related sudden cardiac arrest, and the mechanisms are unclear. We report a unique case of a 19-year-old female who suffered documented prolonged QTc leading to Torsades de pointes and cardiac arrest in the setting of frequent marijuana wax vaping. While she demonstrated normal baseline QTc measurements years earlier, she was found to have a genetic predisposition to QTc prolongation (genetic mutation, family history of prolonged QTc), suggesting that specific patient populations are at higher risk of these adverse events. The patient was acutely managed with isoproterenol to increase the heart rate and was discharged on nadolol after placement of an implantable cardioverter-defibrillator. Marijuana wax vaping and dabbing may cause fatal Torsades de pointes in susceptible patients, and further research is required to identify these patients a priori. |
| format | Article |
| id | doaj-art-03ae0386b4e04566849f080cff081810 |
| institution | Kabale University |
| issn | 2090-6404 2090-6412 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Cardiology |
| spelling | doaj-art-03ae0386b4e04566849f080cff0818102025-02-03T01:26:58ZengWileyCase Reports in Cardiology2090-64042090-64122021-01-01202110.1155/2021/66214966621496Torsades de Pointes due to Excessive Marijuana Use in a Susceptible PatientVivek D. Shah0Adeba Mohammad1Shuktika Nandkeolyar2Liset Stoletniy3Tahmeed Contractor4Department of Internal Medicine, Loma Linda University Medical Center, CA, USADepartment of Internal Medicine, Loma Linda University Medical Center, CA, USADepartment of Internal Medicine, Division of Cardiology, Loma Linda University Medical Center, CA, USADepartment of Internal Medicine, Division of Cardiology, Loma Linda University Medical Center, CA, USADepartment of Internal Medicine, Division of Cardiology, Loma Linda University Medical Center, CA, USAThere are several recent reports of tetrahydrocannabinol vaping-related sudden cardiac arrest, and the mechanisms are unclear. We report a unique case of a 19-year-old female who suffered documented prolonged QTc leading to Torsades de pointes and cardiac arrest in the setting of frequent marijuana wax vaping. While she demonstrated normal baseline QTc measurements years earlier, she was found to have a genetic predisposition to QTc prolongation (genetic mutation, family history of prolonged QTc), suggesting that specific patient populations are at higher risk of these adverse events. The patient was acutely managed with isoproterenol to increase the heart rate and was discharged on nadolol after placement of an implantable cardioverter-defibrillator. Marijuana wax vaping and dabbing may cause fatal Torsades de pointes in susceptible patients, and further research is required to identify these patients a priori.http://dx.doi.org/10.1155/2021/6621496 |
| spellingShingle | Vivek D. Shah Adeba Mohammad Shuktika Nandkeolyar Liset Stoletniy Tahmeed Contractor Torsades de Pointes due to Excessive Marijuana Use in a Susceptible Patient Case Reports in Cardiology |
| title | Torsades de Pointes due to Excessive Marijuana Use in a Susceptible Patient |
| title_full | Torsades de Pointes due to Excessive Marijuana Use in a Susceptible Patient |
| title_fullStr | Torsades de Pointes due to Excessive Marijuana Use in a Susceptible Patient |
| title_full_unstemmed | Torsades de Pointes due to Excessive Marijuana Use in a Susceptible Patient |
| title_short | Torsades de Pointes due to Excessive Marijuana Use in a Susceptible Patient |
| title_sort | torsades de pointes due to excessive marijuana use in a susceptible patient |
| url | http://dx.doi.org/10.1155/2021/6621496 |
| work_keys_str_mv | AT vivekdshah torsadesdepointesduetoexcessivemarijuanauseinasusceptiblepatient AT adebamohammad torsadesdepointesduetoexcessivemarijuanauseinasusceptiblepatient AT shuktikanandkeolyar torsadesdepointesduetoexcessivemarijuanauseinasusceptiblepatient AT lisetstoletniy torsadesdepointesduetoexcessivemarijuanauseinasusceptiblepatient AT tahmeedcontractor torsadesdepointesduetoexcessivemarijuanauseinasusceptiblepatient |