A Rare Case of Benign Oncocytic Cystadenoma of Parotid Gland
Benign oncocytic cystadenoma of the parotid gland is a rare salivary gland tumour, constituting less than 1% of all salivary gland neoplasms. It is characterised by cystic spaces lined with bilayered oncocytic epithelium, composed of eosinophilic granular cytoplasm due to abundant mitochondria. Whil...
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JCDR Research and Publications Private Limited
2025-05-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://jcdr.net/articles/PDF/21011/78727_CE[Ra1]_F(SS)_QC(PS_SS)_PF1(RI_SS)_PFA(IS)_PN(IS).pdf |
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| author | R Prathipa Vimal Chander S Prakashiny |
| author_facet | R Prathipa Vimal Chander S Prakashiny |
| author_sort | R Prathipa |
| collection | DOAJ |
| description | Benign oncocytic cystadenoma of the parotid gland is a rare salivary gland tumour, constituting less than 1% of all salivary gland neoplasms. It is characterised by cystic spaces lined with bilayered oncocytic epithelium, composed of eosinophilic granular cytoplasm due to abundant mitochondria. While these tumours are typically asymptomatic, they can present as painless, slow-growing swellings in the preauricular region, often leading to misdiagnosis as other benign salivary gland tumours. Authors hereby, present the case of a 71-year-old female with recurrent right-sided parotid swelling. Eight years prior, she was diagnosed with low-grade mucoepidermoid carcinoma of the right submandibular gland. One year ago, she underwent total parotidectomy for a recurrent swelling, which was diagnosed histopathologically as a mucus retention cyst. Three months ago, she developed another swelling in the same region, prompting excision and biopsy. Histopathology revealed a cystic lesion lined by bilayered oncocytic epithelium with papillary projections, focal lymphoid aggregates and no evidence of malignancy, confirming oncocytic cystadenoma. Oncocytic cystadenomas present diagnostic challenges due to their rarity and overlap with other salivary gland lesions. Surgical excision is curative, with a low recurrence rate. Awareness of this rare entity is essential for accurate diagnosis and management. |
| format | Article |
| id | doaj-art-03a7ffbd6f6e4bcfa02b8b48b9327a88 |
| institution | OA Journals |
| issn | 2249-782X 0973-709X |
| language | English |
| publishDate | 2025-05-01 |
| publisher | JCDR Research and Publications Private Limited |
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| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj-art-03a7ffbd6f6e4bcfa02b8b48b9327a882025-08-20T01:55:38ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2025-05-01195ED12ED1410.7860/JCDR/2025/78727.21011A Rare Case of Benign Oncocytic Cystadenoma of Parotid GlandR Prathipa0Vimal Chander1S Prakashiny2Postgraduate, Department of Pathology, A.C.S. Medical College and Hospital and Research Institute, Chennai, Tamil Nadu, India.Professor, Department of Pathology, A.C.S. Medical College and Hospital and Research Institute, Chennai, Tamil Nadu, India.Professor, Department of Pathology, A.C.S. Medical College and Hospital and Research Institute, Chennai, Tamil Nadu, India.Benign oncocytic cystadenoma of the parotid gland is a rare salivary gland tumour, constituting less than 1% of all salivary gland neoplasms. It is characterised by cystic spaces lined with bilayered oncocytic epithelium, composed of eosinophilic granular cytoplasm due to abundant mitochondria. While these tumours are typically asymptomatic, they can present as painless, slow-growing swellings in the preauricular region, often leading to misdiagnosis as other benign salivary gland tumours. Authors hereby, present the case of a 71-year-old female with recurrent right-sided parotid swelling. Eight years prior, she was diagnosed with low-grade mucoepidermoid carcinoma of the right submandibular gland. One year ago, she underwent total parotidectomy for a recurrent swelling, which was diagnosed histopathologically as a mucus retention cyst. Three months ago, she developed another swelling in the same region, prompting excision and biopsy. Histopathology revealed a cystic lesion lined by bilayered oncocytic epithelium with papillary projections, focal lymphoid aggregates and no evidence of malignancy, confirming oncocytic cystadenoma. Oncocytic cystadenomas present diagnostic challenges due to their rarity and overlap with other salivary gland lesions. Surgical excision is curative, with a low recurrence rate. Awareness of this rare entity is essential for accurate diagnosis and management.https://jcdr.net/articles/PDF/21011/78727_CE[Ra1]_F(SS)_QC(PS_SS)_PF1(RI_SS)_PFA(IS)_PN(IS).pdfcystic neoplasmparotid tumoursalivary gland |
| spellingShingle | R Prathipa Vimal Chander S Prakashiny A Rare Case of Benign Oncocytic Cystadenoma of Parotid Gland Journal of Clinical and Diagnostic Research cystic neoplasm parotid tumour salivary gland |
| title | A Rare Case of Benign Oncocytic Cystadenoma of Parotid Gland |
| title_full | A Rare Case of Benign Oncocytic Cystadenoma of Parotid Gland |
| title_fullStr | A Rare Case of Benign Oncocytic Cystadenoma of Parotid Gland |
| title_full_unstemmed | A Rare Case of Benign Oncocytic Cystadenoma of Parotid Gland |
| title_short | A Rare Case of Benign Oncocytic Cystadenoma of Parotid Gland |
| title_sort | rare case of benign oncocytic cystadenoma of parotid gland |
| topic | cystic neoplasm parotid tumour salivary gland |
| url | https://jcdr.net/articles/PDF/21011/78727_CE[Ra1]_F(SS)_QC(PS_SS)_PF1(RI_SS)_PFA(IS)_PN(IS).pdf |
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