Development of a chromosomally integrated metabolite-inducible Leu3p-alpha-IPM "off-on" gene switch.
<h4>Background</h4>Present technology uses mostly chimeric proteins as regulators and hormones or antibiotics as signals to induce spatial and temporal gene expression.<h4>Methodology/principal findings</h4>Here, we show that a chromosomally integrated yeast 'Leu3p-alpha...
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| Main Authors: | Maria Poulou, Donald Bell, Kostas Bozonelos, Maria Alexiou, Anthony Gavalas, Robin Lovell-Badge, Eumorphia Remboutsika |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2010-08-01
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| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0012488&type=printable |
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