Development of a chromosomally integrated metabolite-inducible Leu3p-alpha-IPM "off-on" gene switch.

<h4>Background</h4>Present technology uses mostly chimeric proteins as regulators and hormones or antibiotics as signals to induce spatial and temporal gene expression.<h4>Methodology/principal findings</h4>Here, we show that a chromosomally integrated yeast 'Leu3p-alpha...

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Main Authors: Maria Poulou, Donald Bell, Kostas Bozonelos, Maria Alexiou, Anthony Gavalas, Robin Lovell-Badge, Eumorphia Remboutsika
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-08-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0012488&type=printable
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