Mechanistic advances and therapeutic applications of Zingiber officinale Roscoe
Ginger (Zingiber officinale Roscoe) is a plant with promising beneficial effects against various diseases and health disorders. Ginger-rhizome and its essential oils are used in traditional Chinese medicine and Ayurveda as herbal remedies for the treatment of various diseases such as cardiovascular,...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-09-01
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| Series: | Food Chemistry Advances |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772753X25001753 |
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| author | Pawan Kumar Verma Bhawani Singh Priyanka Sharma Sheen Tukra Abderrahmane Aït-Kaddour Zuhaib F. Bhat |
| author_facet | Pawan Kumar Verma Bhawani Singh Priyanka Sharma Sheen Tukra Abderrahmane Aït-Kaddour Zuhaib F. Bhat |
| author_sort | Pawan Kumar Verma |
| collection | DOAJ |
| description | Ginger (Zingiber officinale Roscoe) is a plant with promising beneficial effects against various diseases and health disorders. Ginger-rhizome and its essential oils are used in traditional Chinese medicine and Ayurveda as herbal remedies for the treatment of various diseases such as cardiovascular, inflammatory, neurological, diabetic and nephrological disorders. It has been a part of food and beverages as a spice and appetizer in many cultures. The paper is focused on the pharmacological potential of rhizome and the impact of various isolated compounds on different body systems. The mechanisms responsible for the ethnomedicinal effects are discussed in detail along with recent advances in phytochemistry and phytopharmacology. Various pharmacological activities screened in our laboratory and relevant works of literature available on mechanistic studies have been included to maximize the therapeutic applications of different parts of the plant, especially the rhizome. The plant possesses potent anti-inflammatory, antioxidant, antimicrobial, and anticancer activities due to a wide array of phytochemicals such as gingerols, shogaols, paradols, and zingerones. The wide spectrum of activities of ginger-rhizome reinforces its long-standing use in traditional medicine and presents opportunities for further research in modern pharmacology. |
| format | Article |
| id | doaj-art-039ce54bf0d242ad8e69a4cf256cb94a |
| institution | Kabale University |
| issn | 2772-753X |
| language | English |
| publishDate | 2025-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Food Chemistry Advances |
| spelling | doaj-art-039ce54bf0d242ad8e69a4cf256cb94a2025-08-20T03:50:58ZengElsevierFood Chemistry Advances2772-753X2025-09-01810106010.1016/j.focha.2025.101060Mechanistic advances and therapeutic applications of Zingiber officinale RoscoePawan Kumar Verma0Bhawani Singh1Priyanka Sharma2Sheen Tukra3Abderrahmane Aït-Kaddour4Zuhaib F. Bhat5Division of Veterinary Pharmacology and Toxicology, F.V.Sc., SKUAST-Jammu, J&K, IndiaDivision of Veterinary Pharmacology and Toxicology, F.V.Sc., SKUAST-Jammu, J&K, IndiaDivision of Veterinary Pharmacology and Toxicology, F.V.Sc., SKUAST-Jammu, J&K, IndiaDivision of Veterinary Pharmacology and Toxicology, F.V.Sc., SKUAST-Jammu, J&K, IndiaUniversité Clermont-Auvergne, INRAE, VetAgro Sup, Unité Mixte de Recherche sur le Fromage (UMR F), 89 Avenue de l'Europe, France; Corresponding authors.Division of Livestock Products Technology, SKUAST-Jammu, J&K, India; Corresponding authors.Ginger (Zingiber officinale Roscoe) is a plant with promising beneficial effects against various diseases and health disorders. Ginger-rhizome and its essential oils are used in traditional Chinese medicine and Ayurveda as herbal remedies for the treatment of various diseases such as cardiovascular, inflammatory, neurological, diabetic and nephrological disorders. It has been a part of food and beverages as a spice and appetizer in many cultures. The paper is focused on the pharmacological potential of rhizome and the impact of various isolated compounds on different body systems. The mechanisms responsible for the ethnomedicinal effects are discussed in detail along with recent advances in phytochemistry and phytopharmacology. Various pharmacological activities screened in our laboratory and relevant works of literature available on mechanistic studies have been included to maximize the therapeutic applications of different parts of the plant, especially the rhizome. The plant possesses potent anti-inflammatory, antioxidant, antimicrobial, and anticancer activities due to a wide array of phytochemicals such as gingerols, shogaols, paradols, and zingerones. The wide spectrum of activities of ginger-rhizome reinforces its long-standing use in traditional medicine and presents opportunities for further research in modern pharmacology.http://www.sciencedirect.com/science/article/pii/S2772753X25001753Zingiber officinaleRhizomePhytochemistryAntioxidantAntidiabeticAnti-cancer |
| spellingShingle | Pawan Kumar Verma Bhawani Singh Priyanka Sharma Sheen Tukra Abderrahmane Aït-Kaddour Zuhaib F. Bhat Mechanistic advances and therapeutic applications of Zingiber officinale Roscoe Food Chemistry Advances Zingiber officinale Rhizome Phytochemistry Antioxidant Antidiabetic Anti-cancer |
| title | Mechanistic advances and therapeutic applications of Zingiber officinale Roscoe |
| title_full | Mechanistic advances and therapeutic applications of Zingiber officinale Roscoe |
| title_fullStr | Mechanistic advances and therapeutic applications of Zingiber officinale Roscoe |
| title_full_unstemmed | Mechanistic advances and therapeutic applications of Zingiber officinale Roscoe |
| title_short | Mechanistic advances and therapeutic applications of Zingiber officinale Roscoe |
| title_sort | mechanistic advances and therapeutic applications of zingiber officinale roscoe |
| topic | Zingiber officinale Rhizome Phytochemistry Antioxidant Antidiabetic Anti-cancer |
| url | http://www.sciencedirect.com/science/article/pii/S2772753X25001753 |
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