New approach to the approximation of «dose – effect» dependence during the human somatic cells irradiation

New data on cytogenetic approximation of the experimental cytogenetic dependence "dose - effect" based on the spline regression model that improves biological dosimetry of human radiological exposure were received. This is achieved by reducing the error of the determination of absorbed dos...

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Main Authors: V. F. Chekhun, E. A. Dyomina, M. O. Druzhyna, A. N. Kalinkevich, M. O. Zhovner, S. O. Vershynsky, V. Yu. Storizhko
Format: Article
Language:English
Published: Institute for Nuclear Research, National Academy of Sciences of Ukraine 2013-09-01
Series:Ядерна фізика та енергетика
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Online Access:http://jnpae.kinr.kiev.ua/14.3/Articles_PDF/jnpae-2013-14-0299-Chekhun.pdf
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author V. F. Chekhun
E. A. Dyomina
M. O. Druzhyna
A. N. Kalinkevich
M. O. Zhovner
S. O. Vershynsky
V. Yu. Storizhko
author_facet V. F. Chekhun
E. A. Dyomina
M. O. Druzhyna
A. N. Kalinkevich
M. O. Zhovner
S. O. Vershynsky
V. Yu. Storizhko
author_sort V. F. Chekhun
collection DOAJ
description New data on cytogenetic approximation of the experimental cytogenetic dependence "dose - effect" based on the spline regression model that improves biological dosimetry of human radiological exposure were received. This is achieved by reducing the error of the determination of absorbed dose as compared to the traditional use of linear and linear-quadratic models and makes it possible to predict the effect of dose curves on plateau.
format Article
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institution OA Journals
issn 1818-331X
2074-0565
language English
publishDate 2013-09-01
publisher Institute for Nuclear Research, National Academy of Sciences of Ukraine
record_format Article
series Ядерна фізика та енергетика
spelling doaj-art-0399ffc6eb7a4d9c94c2e2e5855112c62025-08-20T01:59:16ZengInstitute for Nuclear Research, National Academy of Sciences of UkraineЯдерна фізика та енергетика1818-331X2074-05652013-09-01143299303New approach to the approximation of «dose – effect» dependence during the human somatic cells irradiationV. F. Chekhun0E. A. Dyomina1M. O. Druzhyna2A. N. Kalinkevich3M. O. Zhovner4S. O. Vershynsky5V. Yu. Storizhko6R. E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, National Academy of Sciences of Ukraine, Kyiv, UkraineR. E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, National Academy of Sciences of Ukraine, Kyiv, UkraineR. E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, National Academy of Sciences of Ukraine, Kyiv, Ukraine221. Institute of Applied Physics, National Academy of Sciences of Ukraine, Sumy, Ukraine221. Institute of Applied Physics, National Academy of Sciences of Ukraine, Sumy, Ukraine221. Institute of Applied Physics, National Academy of Sciences of Ukraine, Sumy, Ukraine221. Institute of Applied Physics, National Academy of Sciences of Ukraine, Sumy, UkraineNew data on cytogenetic approximation of the experimental cytogenetic dependence "dose - effect" based on the spline regression model that improves biological dosimetry of human radiological exposure were received. This is achieved by reducing the error of the determination of absorbed dose as compared to the traditional use of linear and linear-quadratic models and makes it possible to predict the effect of dose curves on plateau.http://jnpae.kinr.kiev.ua/14.3/Articles_PDF/jnpae-2013-14-0299-Chekhun.pdfirradiationlymphocytechromosome aberrationspline model“dose - effect” dependence
spellingShingle V. F. Chekhun
E. A. Dyomina
M. O. Druzhyna
A. N. Kalinkevich
M. O. Zhovner
S. O. Vershynsky
V. Yu. Storizhko
New approach to the approximation of «dose – effect» dependence during the human somatic cells irradiation
Ядерна фізика та енергетика
irradiation
lymphocyte
chromosome aberration
spline model
“dose - effect” dependence
title New approach to the approximation of «dose – effect» dependence during the human somatic cells irradiation
title_full New approach to the approximation of «dose – effect» dependence during the human somatic cells irradiation
title_fullStr New approach to the approximation of «dose – effect» dependence during the human somatic cells irradiation
title_full_unstemmed New approach to the approximation of «dose – effect» dependence during the human somatic cells irradiation
title_short New approach to the approximation of «dose – effect» dependence during the human somatic cells irradiation
title_sort new approach to the approximation of dose effect dependence during the human somatic cells irradiation
topic irradiation
lymphocyte
chromosome aberration
spline model
“dose - effect” dependence
url http://jnpae.kinr.kiev.ua/14.3/Articles_PDF/jnpae-2013-14-0299-Chekhun.pdf
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