Relationship of D-Dimer, Pt, Aptt, and Albumin with severity and mortality rate in Covid-19 positive patients
COVID-19 is a global health problem that is divided into mild, moderate, and severe degrees of severity and a high mortality rate. The coagulopathy system has value in COVID-19 patients. This study aims to determine the relationship and predictive value of d-dimer, PT, aPTT, and albumin with severit...
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Poltekkes Kemenkes Yogyakarta
2023-08-01
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| Series: | Jurnal Teknologi Laboratorium |
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| Online Access: | https://teknolabjournal.com/index.php/Jtl/article/view/403 |
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| author | Amellya Octifani Budi Santosa Junaedi Wibawa |
| author_facet | Amellya Octifani Budi Santosa Junaedi Wibawa |
| author_sort | Amellya Octifani |
| collection | DOAJ |
| description | COVID-19 is a global health problem that is divided into mild, moderate, and severe degrees of severity and a high mortality rate. The coagulopathy system has value in COVID-19 patients. This study aims to determine the relationship and predictive value of d-dimer, PT, aPTT, and albumin with severity and mortality in COVID-19 positive patients. The type of research used is retrospective with a cross-sectional approach. The research data were taken using a simple random sampling technique from the Medical Record Installation of Husada Utama Hospital, Surabaya in August-September 2021. Bivariate relationship data analysis used the Chi-Square test followed by a multivariate logistic regression test with cut-off values ??of D-dimer, PT, aPTT, and albumin each 0.5 g/mL, 14.0 sec. 36.0 seconds and 3.5 g/dL. The results of the chi-square test (? < 0.05) showed the sig value of D-Dimer, PT, aPTT albumin with a severity level of 0.000; 0.000; 0.001; 0.001 while the value of Sig. with a mortality of 0.000; 0.047; 0.239; 0.022. The results of the multivariate logistic regression test with the degree of severity obtained the value of Sig. 0.000; 0.000; 0.021; 0.000 with a [PR] value of 16.7; 4.4; 2.7; 14.4. The results of the multivariate logistic regression test with mortality obtained the value of Sig. 0.000; 0.020; 0.273 with a [PR] value of 26.9; 2.8;1.6. There is a relationship between D-Dimer, PT, aPTT, and albumin with severity and mortality and can be used as a predictor of severity and mortality in COVID-19 patients. |
| format | Article |
| id | doaj-art-03978218b70c491d99352d4b6b2a8a36 |
| institution | Kabale University |
| issn | 2338-5634 2580-0191 |
| language | Indonesian |
| publishDate | 2023-08-01 |
| publisher | Poltekkes Kemenkes Yogyakarta |
| record_format | Article |
| series | Jurnal Teknologi Laboratorium |
| spelling | doaj-art-03978218b70c491d99352d4b6b2a8a362025-01-03T15:40:13ZindPoltekkes Kemenkes YogyakartaJurnal Teknologi Laboratorium2338-56342580-01912023-08-01121333910.29238/teknolabjournal.v12i1.403355Relationship of D-Dimer, Pt, Aptt, and Albumin with severity and mortality rate in Covid-19 positive patientsAmellya Octifani0Budi Santosa1Junaedi Wibawa2Department of Medical Laboratory Technology, Universitas Muhammadiyah Semarang, IndonesiaUniversitas Muhammadiyah SemarangBendan Hospital, Pekalongan, IndonesiaCOVID-19 is a global health problem that is divided into mild, moderate, and severe degrees of severity and a high mortality rate. The coagulopathy system has value in COVID-19 patients. This study aims to determine the relationship and predictive value of d-dimer, PT, aPTT, and albumin with severity and mortality in COVID-19 positive patients. The type of research used is retrospective with a cross-sectional approach. The research data were taken using a simple random sampling technique from the Medical Record Installation of Husada Utama Hospital, Surabaya in August-September 2021. Bivariate relationship data analysis used the Chi-Square test followed by a multivariate logistic regression test with cut-off values ??of D-dimer, PT, aPTT, and albumin each 0.5 g/mL, 14.0 sec. 36.0 seconds and 3.5 g/dL. The results of the chi-square test (? < 0.05) showed the sig value of D-Dimer, PT, aPTT albumin with a severity level of 0.000; 0.000; 0.001; 0.001 while the value of Sig. with a mortality of 0.000; 0.047; 0.239; 0.022. The results of the multivariate logistic regression test with the degree of severity obtained the value of Sig. 0.000; 0.000; 0.021; 0.000 with a [PR] value of 16.7; 4.4; 2.7; 14.4. The results of the multivariate logistic regression test with mortality obtained the value of Sig. 0.000; 0.020; 0.273 with a [PR] value of 26.9; 2.8;1.6. There is a relationship between D-Dimer, PT, aPTT, and albumin with severity and mortality and can be used as a predictor of severity and mortality in COVID-19 patients.https://teknolabjournal.com/index.php/Jtl/article/view/403keywords: d-dimer; pt (prothrombin time); aptt (activated partial thromboplastin time); albumin; severity and mortality rate |
| spellingShingle | Amellya Octifani Budi Santosa Junaedi Wibawa Relationship of D-Dimer, Pt, Aptt, and Albumin with severity and mortality rate in Covid-19 positive patients Jurnal Teknologi Laboratorium keywords: d-dimer; pt (prothrombin time); aptt (activated partial thromboplastin time); albumin; severity and mortality rate |
| title | Relationship of D-Dimer, Pt, Aptt, and Albumin with severity and mortality rate in Covid-19 positive patients |
| title_full | Relationship of D-Dimer, Pt, Aptt, and Albumin with severity and mortality rate in Covid-19 positive patients |
| title_fullStr | Relationship of D-Dimer, Pt, Aptt, and Albumin with severity and mortality rate in Covid-19 positive patients |
| title_full_unstemmed | Relationship of D-Dimer, Pt, Aptt, and Albumin with severity and mortality rate in Covid-19 positive patients |
| title_short | Relationship of D-Dimer, Pt, Aptt, and Albumin with severity and mortality rate in Covid-19 positive patients |
| title_sort | relationship of d dimer pt aptt and albumin with severity and mortality rate in covid 19 positive patients |
| topic | keywords: d-dimer; pt (prothrombin time); aptt (activated partial thromboplastin time); albumin; severity and mortality rate |
| url | https://teknolabjournal.com/index.php/Jtl/article/view/403 |
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