Magnetic Nanoparticles for Targeting and Imaging of Stem Cells in Myocardial Infarction
Stem cell therapy has broad applications in regenerative medicine and increasingly within cardiovascular disease. Stem cells have emerged as a leading therapeutic option for many diseases and have broad applications in regenerative medicine. Injuries to the heart are often permanent due to the limit...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Stem Cells International |
| Online Access: | http://dx.doi.org/10.1155/2016/4198790 |
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| _version_ | 1832559877031985152 |
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| author | Michelle R. Santoso Phillip C. Yang |
| author_facet | Michelle R. Santoso Phillip C. Yang |
| author_sort | Michelle R. Santoso |
| collection | DOAJ |
| description | Stem cell therapy has broad applications in regenerative medicine and increasingly within cardiovascular disease. Stem cells have emerged as a leading therapeutic option for many diseases and have broad applications in regenerative medicine. Injuries to the heart are often permanent due to the limited proliferation and self-healing capability of cardiomyocytes; as such, stem cell therapy has become increasingly important in the treatment of cardiovascular diseases. Despite extensive efforts to optimize cardiac stem cell therapy, challenges remain in the delivery and monitoring of cells injected into the myocardium. Other fields have successively used nanoscience and nanotechnology for a multitude of biomedical applications, including drug delivery, targeted imaging, hyperthermia, and tissue repair. In particular, superparamagnetic iron oxide nanoparticles (SPIONs) have been widely employed for molecular and cellular imaging. In this mini-review, we focus on the application of superparamagnetic iron oxide nanoparticles in targeting and monitoring of stem cells for the treatment of myocardial infarctions. |
| format | Article |
| id | doaj-art-038833af1009433bb829f5b9ce93073c |
| institution | Kabale University |
| issn | 1687-966X 1687-9678 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Stem Cells International |
| spelling | doaj-art-038833af1009433bb829f5b9ce93073c2025-02-03T01:28:58ZengWileyStem Cells International1687-966X1687-96782016-01-01201610.1155/2016/41987904198790Magnetic Nanoparticles for Targeting and Imaging of Stem Cells in Myocardial InfarctionMichelle R. Santoso0Phillip C. Yang1Division of Cardiovascular Medicine, Stanford University, Stanford, CA 94305, USADivision of Cardiovascular Medicine, Stanford University, Stanford, CA 94305, USAStem cell therapy has broad applications in regenerative medicine and increasingly within cardiovascular disease. Stem cells have emerged as a leading therapeutic option for many diseases and have broad applications in regenerative medicine. Injuries to the heart are often permanent due to the limited proliferation and self-healing capability of cardiomyocytes; as such, stem cell therapy has become increasingly important in the treatment of cardiovascular diseases. Despite extensive efforts to optimize cardiac stem cell therapy, challenges remain in the delivery and monitoring of cells injected into the myocardium. Other fields have successively used nanoscience and nanotechnology for a multitude of biomedical applications, including drug delivery, targeted imaging, hyperthermia, and tissue repair. In particular, superparamagnetic iron oxide nanoparticles (SPIONs) have been widely employed for molecular and cellular imaging. In this mini-review, we focus on the application of superparamagnetic iron oxide nanoparticles in targeting and monitoring of stem cells for the treatment of myocardial infarctions.http://dx.doi.org/10.1155/2016/4198790 |
| spellingShingle | Michelle R. Santoso Phillip C. Yang Magnetic Nanoparticles for Targeting and Imaging of Stem Cells in Myocardial Infarction Stem Cells International |
| title | Magnetic Nanoparticles for Targeting and Imaging of Stem Cells in Myocardial Infarction |
| title_full | Magnetic Nanoparticles for Targeting and Imaging of Stem Cells in Myocardial Infarction |
| title_fullStr | Magnetic Nanoparticles for Targeting and Imaging of Stem Cells in Myocardial Infarction |
| title_full_unstemmed | Magnetic Nanoparticles for Targeting and Imaging of Stem Cells in Myocardial Infarction |
| title_short | Magnetic Nanoparticles for Targeting and Imaging of Stem Cells in Myocardial Infarction |
| title_sort | magnetic nanoparticles for targeting and imaging of stem cells in myocardial infarction |
| url | http://dx.doi.org/10.1155/2016/4198790 |
| work_keys_str_mv | AT michellersantoso magneticnanoparticlesfortargetingandimagingofstemcellsinmyocardialinfarction AT phillipcyang magneticnanoparticlesfortargetingandimagingofstemcellsinmyocardialinfarction |