BCMA-targeted therapies for multiple myeloma: latest updates from 2024 ASH annual meeting

Abstract B-cell maturation antigen (BCMA) is currently the most extensively explored target for multiple myeloma (MM). BCMA-targeted therapies such as antibody-drug conjugate (ADC), bispecific antibodies (BsAbs), chimeric antigen receptor T(CAR-T) cell have shown promising therapeutic prospects in M...

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Main Authors: Huijian Zheng, Huajian Xian, Wenjie Zhang, Chaoqun Lu, Renyao Pan, Han Liu, Zhenshu Xu
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Journal of Hematology & Oncology
Subjects:
Online Access:https://doi.org/10.1186/s13045-025-01675-5
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author Huijian Zheng
Huajian Xian
Wenjie Zhang
Chaoqun Lu
Renyao Pan
Han Liu
Zhenshu Xu
author_facet Huijian Zheng
Huajian Xian
Wenjie Zhang
Chaoqun Lu
Renyao Pan
Han Liu
Zhenshu Xu
author_sort Huijian Zheng
collection DOAJ
description Abstract B-cell maturation antigen (BCMA) is currently the most extensively explored target for multiple myeloma (MM). BCMA-targeted therapies such as antibody-drug conjugate (ADC), bispecific antibodies (BsAbs), chimeric antigen receptor T(CAR-T) cell have shown promising therapeutic prospects in MM. We have summarized the latest reports on the three types of drugs for MM at the 2024 ASH Annual Meeting.
format Article
id doaj-art-037e45ce3b4142e0884e39c2707cfda0
institution OA Journals
issn 1756-8722
language English
publishDate 2025-03-01
publisher BMC
record_format Article
series Journal of Hematology & Oncology
spelling doaj-art-037e45ce3b4142e0884e39c2707cfda02025-08-20T02:01:34ZengBMCJournal of Hematology & Oncology1756-87222025-03-011811410.1186/s13045-025-01675-5BCMA-targeted therapies for multiple myeloma: latest updates from 2024 ASH annual meetingHuijian Zheng0Huajian Xian1Wenjie Zhang2Chaoqun Lu3Renyao Pan4Han Liu5Zhenshu Xu6Fujian Provincial Key Laboratory on Hematology, Fujian Institute of Hematology, Fujian Medical University Union HospitalShanghai Institute of Hematology, State Key Laboratory of Medical Genomics, Ruijin Hospital, National Research Center for Translational Medicine at Shanghai, Shanghai Jiao Tong University School of MedicineFujian Provincial Key Laboratory on Hematology, Fujian Institute of Hematology, Fujian Medical University Union HospitalShanghai Institute of Hematology, State Key Laboratory of Medical Genomics, Ruijin Hospital, National Research Center for Translational Medicine at Shanghai, Shanghai Jiao Tong University School of MedicineFujian Provincial Key Laboratory on Hematology, Fujian Institute of Hematology, Fujian Medical University Union HospitalShanghai Institute of Hematology, State Key Laboratory of Medical Genomics, Ruijin Hospital, National Research Center for Translational Medicine at Shanghai, Shanghai Jiao Tong University School of MedicineFujian Provincial Key Laboratory on Hematology, Fujian Institute of Hematology, Fujian Medical University Union HospitalAbstract B-cell maturation antigen (BCMA) is currently the most extensively explored target for multiple myeloma (MM). BCMA-targeted therapies such as antibody-drug conjugate (ADC), bispecific antibodies (BsAbs), chimeric antigen receptor T(CAR-T) cell have shown promising therapeutic prospects in MM. We have summarized the latest reports on the three types of drugs for MM at the 2024 ASH Annual Meeting.https://doi.org/10.1186/s13045-025-01675-5BCMA-targeted therapiesMultiple myelomaASH 2024
spellingShingle Huijian Zheng
Huajian Xian
Wenjie Zhang
Chaoqun Lu
Renyao Pan
Han Liu
Zhenshu Xu
BCMA-targeted therapies for multiple myeloma: latest updates from 2024 ASH annual meeting
Journal of Hematology & Oncology
BCMA-targeted therapies
Multiple myeloma
ASH 2024
title BCMA-targeted therapies for multiple myeloma: latest updates from 2024 ASH annual meeting
title_full BCMA-targeted therapies for multiple myeloma: latest updates from 2024 ASH annual meeting
title_fullStr BCMA-targeted therapies for multiple myeloma: latest updates from 2024 ASH annual meeting
title_full_unstemmed BCMA-targeted therapies for multiple myeloma: latest updates from 2024 ASH annual meeting
title_short BCMA-targeted therapies for multiple myeloma: latest updates from 2024 ASH annual meeting
title_sort bcma targeted therapies for multiple myeloma latest updates from 2024 ash annual meeting
topic BCMA-targeted therapies
Multiple myeloma
ASH 2024
url https://doi.org/10.1186/s13045-025-01675-5
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