Optimal Sca-1-based procedure for purifying mouse adipose-derived mesenchymal stem cells with enhanced proliferative and differentiation potential

Optimal Sca-1-based procedure for purifying mouse adipose-derived mesenchymal stem cells with enhanced proliferative and differentiation potential

IntroductionAdipose-derived mesenchymal stem cells (ADSCs) are promising candidates for mesenchymal stem cell (MSC) therapy due to their ease of isolation from the stromal vascular fraction (SVF) of adipose tissue. However, traditional isolation methods often result in mouse ADSCs with low purity an...

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Bibliographic Details
Main Authors: Xingyu Tao, Jialian Wang, Yuan Yan, Peifeng Cheng, Bin Liu, Huimin Du, Bailin Niu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
adipose-derived mesenchymal stem cells
Sca-1
vascular stem cells
heterogeneity
purification
magnetic activated cell sorting
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2025.1566670/full
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