Arteriovenous fistula for hemodialysis in relation to the timing of creation: analysis of key factors

Timely creation of an arteriovenous fistula is not always feasible. The aim was to determine the key factors for functionality and maturation of arteriovenous fistulas in relation to timing of its creation. The research was conducted at the Department of Nephrology and Dialysis, Kragujevac Univer...

Full description

Saved in:
Bibliographic Details
Main Authors: Radojica V. Stolić, Mirjana Pajčin, Vekoslav Mitrović, Nataša D. Zdravković, Saša Sovtić=, Snežana Marković-Jovanović, Slavica Pajović, Kristina Bulatović, Branka Mitić, Dragiša Rašić
Format: Article
Language:English
Published: Sestre Milosrdnice University hospital, Institute of Clinical Medical Research 2024-01-01
Series:Acta Clinica Croatica
Subjects:
Online Access:https://hrcak.srce.hr/file/474039
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849721175806050304
author Radojica V. Stolić
Mirjana Pajčin
Vekoslav Mitrović
Nataša D. Zdravković
Saša Sovtić=
Snežana Marković-Jovanović
Slavica Pajović
Kristina Bulatović
Branka Mitić
Dragiša Rašić
author_facet Radojica V. Stolić
Mirjana Pajčin
Vekoslav Mitrović
Nataša D. Zdravković
Saša Sovtić=
Snežana Marković-Jovanović
Slavica Pajović
Kristina Bulatović
Branka Mitić
Dragiša Rašić
author_sort Radojica V. Stolić
collection DOAJ
description Timely creation of an arteriovenous fistula is not always feasible. The aim was to determine the key factors for functionality and maturation of arteriovenous fistulas in relation to timing of its creation. The research was conducted at the Department of Nephrology and Dialysis, Kragujevac University Clinical Center, Kragujevac, Serbia, in patients who had had a fistula surgically created over a period of fifteen years. A total of 1089 patients were registered. All clinical and biochemical parameters that were of interest for this study were analyzed. The group of patients with fistulas created before the start of hemodialysis was statistically different from the group of patients whose fistulas were created after the start of hemodialysis according to vein lumen (p=0.005), systolic blood pressure (p<0.001), total cholesterol (p<0.001), HDL cholesterol (p=0.008) and LDL cholesterol (p<0.001). Predictive parameters of the initial dysfunction were vein diameter (p=0.004), cholesterol (p=0.008) and LDL cholesterol (p=0.033), while the maturation parameter was systolic blood pressure (p=0.042). In conclusion, predictive parameters of initial fistula dysfunction are vein diameter, cholesterol and LDL cholesterol, while systolic blood pressure is most important for maturation.
format Article
id doaj-art-035355ac53e2406eb0d18d53388cbd70
institution DOAJ
issn 0353-9466
1333-9451
language English
publishDate 2024-01-01
publisher Sestre Milosrdnice University hospital, Institute of Clinical Medical Research
record_format Article
series Acta Clinica Croatica
spelling doaj-art-035355ac53e2406eb0d18d53388cbd702025-08-20T03:11:43ZengSestre Milosrdnice University hospital, Institute of Clinical Medical ResearchActa Clinica Croatica0353-94661333-94512024-01-0163.236837510.20471/acc.2024.63.02.13Arteriovenous fistula for hemodialysis in relation to the timing of creation: analysis of key factorsRadojica V. Stolić0Mirjana Pajčin1Vekoslav Mitrović2Nataša D. Zdravković3Saša Sovtić=4Snežana Marković-Jovanović5Slavica Pajović6Kristina Bulatović7Branka Mitić8Dragiša Rašić9University of Kragujevac, Faculty of Medical Sciences, Department of Internal Medicine, Kragujevac, SerbiaUniversity of Pristina/Kosovska Mitrovica, Faculty of Medicine, Pristina/Kosovska Mitrovica, SerbiaUniversity of East Sarajevo, Faculty of Medicine, Republika Srpska, Foča, Bosnia and HerzegovinaUniversity of Kragujevac, Faculty of Medical Sciences, Department of Internal Medicine, Kragujevac, SerbiaUniversity of Pristina/Kosovska Mitrovica, Faculty of Medicine, Pristina/Kosovska Mitrovica, SerbiaUniversity of Pristina/Kosovska Mitrovica, Faculty of Medicine, Pristina/Kosovska Mitrovica, SerbiaUniversity of Pristina/Kosovska Mitrovica, Faculty of Medicine, Pristina/Kosovska Mitrovica, SerbiaUniversity of Pristina/Kosovska Mitrovica, Faculty of Medicine, Pristina/Kosovska Mitrovica, SerbiaUniversity of Niš, Faculty of Medicine, Niš, SerbiaUniversity of Pristina/Kosovska Mitrovica, Faculty of Medicine, Pristina/Kosovska Mitrovica, SerbiaTimely creation of an arteriovenous fistula is not always feasible. The aim was to determine the key factors for functionality and maturation of arteriovenous fistulas in relation to timing of its creation. The research was conducted at the Department of Nephrology and Dialysis, Kragujevac University Clinical Center, Kragujevac, Serbia, in patients who had had a fistula surgically created over a period of fifteen years. A total of 1089 patients were registered. All clinical and biochemical parameters that were of interest for this study were analyzed. The group of patients with fistulas created before the start of hemodialysis was statistically different from the group of patients whose fistulas were created after the start of hemodialysis according to vein lumen (p=0.005), systolic blood pressure (p<0.001), total cholesterol (p<0.001), HDL cholesterol (p=0.008) and LDL cholesterol (p<0.001). Predictive parameters of the initial dysfunction were vein diameter (p=0.004), cholesterol (p=0.008) and LDL cholesterol (p=0.033), while the maturation parameter was systolic blood pressure (p=0.042). In conclusion, predictive parameters of initial fistula dysfunction are vein diameter, cholesterol and LDL cholesterol, while systolic blood pressure is most important for maturation.https://hrcak.srce.hr/file/474039Predictive parametersInitial functionMaturationArteriovenous fistulaTiming of creation
spellingShingle Radojica V. Stolić
Mirjana Pajčin
Vekoslav Mitrović
Nataša D. Zdravković
Saša Sovtić=
Snežana Marković-Jovanović
Slavica Pajović
Kristina Bulatović
Branka Mitić
Dragiša Rašić
Arteriovenous fistula for hemodialysis in relation to the timing of creation: analysis of key factors
Acta Clinica Croatica
Predictive parameters
Initial function
Maturation
Arteriovenous fistula
Timing of creation
title Arteriovenous fistula for hemodialysis in relation to the timing of creation: analysis of key factors
title_full Arteriovenous fistula for hemodialysis in relation to the timing of creation: analysis of key factors
title_fullStr Arteriovenous fistula for hemodialysis in relation to the timing of creation: analysis of key factors
title_full_unstemmed Arteriovenous fistula for hemodialysis in relation to the timing of creation: analysis of key factors
title_short Arteriovenous fistula for hemodialysis in relation to the timing of creation: analysis of key factors
title_sort arteriovenous fistula for hemodialysis in relation to the timing of creation analysis of key factors
topic Predictive parameters
Initial function
Maturation
Arteriovenous fistula
Timing of creation
url https://hrcak.srce.hr/file/474039
work_keys_str_mv AT radojicavstolic arteriovenousfistulaforhemodialysisinrelationtothetimingofcreationanalysisofkeyfactors
AT mirjanapajcin arteriovenousfistulaforhemodialysisinrelationtothetimingofcreationanalysisofkeyfactors
AT vekoslavmitrovic arteriovenousfistulaforhemodialysisinrelationtothetimingofcreationanalysisofkeyfactors
AT natasadzdravkovic arteriovenousfistulaforhemodialysisinrelationtothetimingofcreationanalysisofkeyfactors
AT sasasovtic arteriovenousfistulaforhemodialysisinrelationtothetimingofcreationanalysisofkeyfactors
AT snezanamarkovicjovanovic arteriovenousfistulaforhemodialysisinrelationtothetimingofcreationanalysisofkeyfactors
AT slavicapajovic arteriovenousfistulaforhemodialysisinrelationtothetimingofcreationanalysisofkeyfactors
AT kristinabulatovic arteriovenousfistulaforhemodialysisinrelationtothetimingofcreationanalysisofkeyfactors
AT brankamitic arteriovenousfistulaforhemodialysisinrelationtothetimingofcreationanalysisofkeyfactors
AT dragisarasic arteriovenousfistulaforhemodialysisinrelationtothetimingofcreationanalysisofkeyfactors