Harnessing the highly adaptable barnase-barstar system for genetic biocontrol of Aedes aegypti

Abstract Toxin-antidote pairs can be used in gene drive systems, providing powerful means to modify mosquito populations. Here we use the toxin-antidote pair, barnase and barstar, originally identified in Bacillus amyloliquefaciens, due to their high binding affinity, small size and lack of need for...

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Bibliographic Details
Main Authors: Katherine Nevard, Joshua X. D. Ang, Michelle A. E. Anderson, Estela Gonzalez, Lewis Shackleford, Luke Alphey
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08588-6
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