Harnessing the highly adaptable barnase-barstar system for genetic biocontrol of Aedes aegypti
Abstract Toxin-antidote pairs can be used in gene drive systems, providing powerful means to modify mosquito populations. Here we use the toxin-antidote pair, barnase and barstar, originally identified in Bacillus amyloliquefaciens, due to their high binding affinity, small size and lack of need for...
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| Main Authors: | Katherine Nevard, Joshua X. D. Ang, Michelle A. E. Anderson, Estela Gonzalez, Lewis Shackleford, Luke Alphey |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-08-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-025-08588-6 |
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