Differential Effects of Rutin and Its Aglycone Quercetin on Cytotoxicity and Chemosensitization of HCT 116 Colon Cancer Cells to Anticancer Drugs 5-Fluorouracil and Doxorubicin

Differential Effects of Rutin and Its Aglycone Quercetin on Cytotoxicity and Chemosensitization of HCT 116 Colon Cancer Cells to Anticancer Drugs 5-Fluorouracil and Doxorubicin

Background: Rutin and quercetin are natural flavonoids with a variety of beneficial health effects, including anticancer activity. In the present study, we compared cytotoxicity and chemosensitization of human colon cancer HCT116 cells to anticancer drugs 5-fluorouracil (5-FU) and doxorubicin (DOX)...

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Bibliographic Details
Main Authors: Iva Suman, Alberta Jezidžić, Dorotea Dobrić, Robert Domitrović
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Biology
Subjects:
rutin
quercetin
flavonoids
5-fluorouracil
doxorubicin
colon cancer
Online Access:https://www.mdpi.com/2079-7737/14/5/527
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