Electrophysiological Evaluation of a Sciatic Nerve Degree III Injury Model in Rats
Sciatic nerve injury is a prevalent traumatic condition that significantly impacts a patient's quality of life. The sciatic nerve compression injury model is among the most commonly utilized models for investigating nerve repair and regeneration. Within this context, the degree III sciatic n...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Bio-protocol LLC
2025-05-01
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| Series: | Bio-Protocol |
| Online Access: | https://bio-protocol.org/en/bpdetail?id=5311&type=0 |
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| Summary: | Sciatic nerve injury is a prevalent traumatic condition that significantly impacts a patient's quality of life. The sciatic nerve compression injury model is among the most commonly utilized models for investigating nerve repair and regeneration. Within this context, the degree III sciatic nerve injury model is frequently employed in scientific research due to its clinical relevance and its suitability for studies focused on functional recovery. However, a standardized approach for accurately assessing the success of constructing the degree III sciatic nerve injury model remains lacking. Traditional macroscopic observation methods exhibit limitations, whereas neurophysiological testing serves as a highly sensitive and objective evaluation technique that can directly reflect changes in nerve conduction function, thus providing reliable quantitative evidence for the successful establishment of the model. This study aims to offer a comprehensive description of the application of neurophysiological techniques in evaluating the construction of the degree III sciatic nerve injury model, thereby ensuring the success of model preparation. |
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| ISSN: | 2331-8325 |