Analysis of the relationship between abdominal aortic calcification and frailty in the middle-aged and older US population
Background and Objective: Abdominal aortic calcification (AAC) is a marker of cardiovascular disease and is associated with increased mortality in middle-aged and older populations. However, its relationship with frailty remains unclear.Methods: Data were obtained from the 2013–2014 National Health...
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| Language: | English |
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Elsevier
2025-03-01
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| Series: | Preventive Medicine Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211335525000336 |
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| author | Rena Rehemuding Kaisaierjiang Kadier Xinliang Peng Pengfei Liu Diliyaer Dilixiati Aikeliyaer Ainiwaer Xiaozhu Liu Xiangtao Liu Xiang Ma |
| author_facet | Rena Rehemuding Kaisaierjiang Kadier Xinliang Peng Pengfei Liu Diliyaer Dilixiati Aikeliyaer Ainiwaer Xiaozhu Liu Xiangtao Liu Xiang Ma |
| author_sort | Rena Rehemuding |
| collection | DOAJ |
| description | Background and Objective: Abdominal aortic calcification (AAC) is a marker of cardiovascular disease and is associated with increased mortality in middle-aged and older populations. However, its relationship with frailty remains unclear.Methods: Data were obtained from the 2013–2014 National Health and Nutrition Examination Survey. AAC was quantified using the Kauppila scoring system based on dual-energy X-ray absorptiometry. Frailty was assessed using the frailty index. Multivariable logistic regression models examined the association between AAC and frailty.Results: A total of 2987 adults aged ≥40 years were included. Compared to individuals with an AAC-8 score of 0, low-risk (AAC-8 score = 1–2; OR: 1.24; 95 % CI, 1.00–1.53) and high-risk AAC (AAC-8 score ≥ 3; OR: 1.83; 95 % CI, 1.03–3.23) were associated with higher odds of frailty. Similarly, mild to moderate AAC (0 < AAC-24 score ≤ 6; OR: 1.26; 95 % CI, 1.03–1.54) and severe AAC (AAC-24 score > 6; OR: 1.79; 95 % CI, 1.07–2.99) showed positive associations with frailty.Conclusions: Among middle-aged and older populations in the United States, there exists a positive correlation between AAC and frailty. Our findings suggest that the AAC score holds promise as a valuable tool for the early identification of frailty. |
| format | Article |
| id | doaj-art-033fa5638b2d45b6b4e52fca931fa6bd |
| institution | Kabale University |
| issn | 2211-3355 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Preventive Medicine Reports |
| spelling | doaj-art-033fa5638b2d45b6b4e52fca931fa6bd2025-02-09T05:00:04ZengElsevierPreventive Medicine Reports2211-33552025-03-0151102994Analysis of the relationship between abdominal aortic calcification and frailty in the middle-aged and older US populationRena Rehemuding0Kaisaierjiang Kadier1Xinliang Peng2Pengfei Liu3Diliyaer Dilixiati4Aikeliyaer Ainiwaer5Xiaozhu Liu6Xiangtao Liu7Xiang Ma8Department of Cardiology, First Affiliated Hospital of Xinjiang Medical University, Urumqi, ChinaDepartment of Cardiology, First Affiliated Hospital of Xinjiang Medical University, Urumqi, ChinaDepartment of Cardiology, First Affiliated Hospital of Xinjiang Medical University, Urumqi, ChinaDepartment of Cardiology, First Affiliated Hospital of Xinjiang Medical University, Urumqi, ChinaDepartment of Urology, First Affiliated Hospital of Xinjiang Medical University, Urumqi, ChinaDepartment of Physiology, Cardiovascular Research Institute Maastricht (CARIM), Maastricht, NetherlandsEmergency and Critical Care Medical Center, Beijing Shijitan Hospital, Capital Medical University, Beijing, ChinaCollege of Medical Engineering and Technology, Xinjiang Medical University, Urumqi, China; Correspondence to: College of Medical Engineering and Technology, Xinjiang Medical University, Shangde North Road No. 567, Urumqi 830017, China.Department of Cardiology, First Affiliated Hospital of Xinjiang Medical University, Urumqi, China; Correspondence to: Department of Cardiology, First Affiliated Hospital of Xinjiang Medical University, Xinyi Road No. 393, Urumqi 830054, China.Background and Objective: Abdominal aortic calcification (AAC) is a marker of cardiovascular disease and is associated with increased mortality in middle-aged and older populations. However, its relationship with frailty remains unclear.Methods: Data were obtained from the 2013–2014 National Health and Nutrition Examination Survey. AAC was quantified using the Kauppila scoring system based on dual-energy X-ray absorptiometry. Frailty was assessed using the frailty index. Multivariable logistic regression models examined the association between AAC and frailty.Results: A total of 2987 adults aged ≥40 years were included. Compared to individuals with an AAC-8 score of 0, low-risk (AAC-8 score = 1–2; OR: 1.24; 95 % CI, 1.00–1.53) and high-risk AAC (AAC-8 score ≥ 3; OR: 1.83; 95 % CI, 1.03–3.23) were associated with higher odds of frailty. Similarly, mild to moderate AAC (0 < AAC-24 score ≤ 6; OR: 1.26; 95 % CI, 1.03–1.54) and severe AAC (AAC-24 score > 6; OR: 1.79; 95 % CI, 1.07–2.99) showed positive associations with frailty.Conclusions: Among middle-aged and older populations in the United States, there exists a positive correlation between AAC and frailty. Our findings suggest that the AAC score holds promise as a valuable tool for the early identification of frailty.http://www.sciencedirect.com/science/article/pii/S2211335525000336Abdominal aortic calcificationFrailtyNational Health and nutrition examination surveyPopulation health |
| spellingShingle | Rena Rehemuding Kaisaierjiang Kadier Xinliang Peng Pengfei Liu Diliyaer Dilixiati Aikeliyaer Ainiwaer Xiaozhu Liu Xiangtao Liu Xiang Ma Analysis of the relationship between abdominal aortic calcification and frailty in the middle-aged and older US population Preventive Medicine Reports Abdominal aortic calcification Frailty National Health and nutrition examination survey Population health |
| title | Analysis of the relationship between abdominal aortic calcification and frailty in the middle-aged and older US population |
| title_full | Analysis of the relationship between abdominal aortic calcification and frailty in the middle-aged and older US population |
| title_fullStr | Analysis of the relationship between abdominal aortic calcification and frailty in the middle-aged and older US population |
| title_full_unstemmed | Analysis of the relationship between abdominal aortic calcification and frailty in the middle-aged and older US population |
| title_short | Analysis of the relationship between abdominal aortic calcification and frailty in the middle-aged and older US population |
| title_sort | analysis of the relationship between abdominal aortic calcification and frailty in the middle aged and older us population |
| topic | Abdominal aortic calcification Frailty National Health and nutrition examination survey Population health |
| url | http://www.sciencedirect.com/science/article/pii/S2211335525000336 |
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