The first case of isolation of Magnusiomyces capitatus from the oral cavity of an addicted patient
Magnusiomyces capitatus (M. capitatus) is an emerging opportunistic yeast, rarely found as a causal agent of invasive fungal infection. In this study, we report a 31-year-old man infected with M. capitatus in the oral cavity, with a history of heroin and amphetamine abuse. M. capitatus was isolated...
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| Language: | English |
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The Journal of Infection in Developing Countries
2024-02-01
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| Series: | Journal of Infection in Developing Countries |
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| Online Access: | https://jidc.org/index.php/journal/article/view/18099 |
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| author | Aynaz Ghojoghi Sadegh Khodavaisy Ali Zarei Mahmoudabadi Maryam Hatami Mahnaz Fatahinia |
| author_facet | Aynaz Ghojoghi Sadegh Khodavaisy Ali Zarei Mahmoudabadi Maryam Hatami Mahnaz Fatahinia |
| author_sort | Aynaz Ghojoghi |
| collection | DOAJ |
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Magnusiomyces capitatus (M. capitatus) is an emerging opportunistic yeast, rarely found as a causal agent of invasive fungal infection. In this study, we report a 31-year-old man infected with M. capitatus in the oral cavity, with a history of heroin and amphetamine abuse. M. capitatus was isolated through culture and microscopic analysis and identified by PCR amplification of the ITS DNA region. Based on the in vitro antifungal susceptibility test, the lowest MICs for M. capitatus were recorded for nystatin, itraconazole, and amphotericin, while higher MICs were observed for caspofungin and fluconazole. Treatment with nystatin successfully eliminated M. capitatus and relieved the clinical symptoms. This study presents the first case of M. capitatus in a patient with substance use disorder, manifesting as a plaque-like ulcer in the oral cavity.
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| format | Article |
| id | doaj-art-033f61102d1e42f99641d615af93cc0e |
| institution | Kabale University |
| issn | 1972-2680 |
| language | English |
| publishDate | 2024-02-01 |
| publisher | The Journal of Infection in Developing Countries |
| record_format | Article |
| series | Journal of Infection in Developing Countries |
| spelling | doaj-art-033f61102d1e42f99641d615af93cc0e2025-08-20T03:52:39ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802024-02-01180210.3855/jidc.18099The first case of isolation of Magnusiomyces capitatus from the oral cavity of an addicted patientAynaz Ghojoghi0Sadegh Khodavaisy1Ali Zarei Mahmoudabadi2Maryam Hatami3Mahnaz Fatahinia4Department of Medical Mycology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IranDepartment of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, IranDepartment of Medical Mycology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IranDepartment of Medical Mycology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IranDepartment of Medical Mycology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran Magnusiomyces capitatus (M. capitatus) is an emerging opportunistic yeast, rarely found as a causal agent of invasive fungal infection. In this study, we report a 31-year-old man infected with M. capitatus in the oral cavity, with a history of heroin and amphetamine abuse. M. capitatus was isolated through culture and microscopic analysis and identified by PCR amplification of the ITS DNA region. Based on the in vitro antifungal susceptibility test, the lowest MICs for M. capitatus were recorded for nystatin, itraconazole, and amphotericin, while higher MICs were observed for caspofungin and fluconazole. Treatment with nystatin successfully eliminated M. capitatus and relieved the clinical symptoms. This study presents the first case of M. capitatus in a patient with substance use disorder, manifesting as a plaque-like ulcer in the oral cavity. https://jidc.org/index.php/journal/article/view/18099GeotrichumMagnusiomyces capitatusdiagnosisaddictionnystatin |
| spellingShingle | Aynaz Ghojoghi Sadegh Khodavaisy Ali Zarei Mahmoudabadi Maryam Hatami Mahnaz Fatahinia The first case of isolation of Magnusiomyces capitatus from the oral cavity of an addicted patient Journal of Infection in Developing Countries Geotrichum Magnusiomyces capitatus diagnosis addiction nystatin |
| title | The first case of isolation of Magnusiomyces capitatus from the oral cavity of an addicted patient |
| title_full | The first case of isolation of Magnusiomyces capitatus from the oral cavity of an addicted patient |
| title_fullStr | The first case of isolation of Magnusiomyces capitatus from the oral cavity of an addicted patient |
| title_full_unstemmed | The first case of isolation of Magnusiomyces capitatus from the oral cavity of an addicted patient |
| title_short | The first case of isolation of Magnusiomyces capitatus from the oral cavity of an addicted patient |
| title_sort | first case of isolation of magnusiomyces capitatus from the oral cavity of an addicted patient |
| topic | Geotrichum Magnusiomyces capitatus diagnosis addiction nystatin |
| url | https://jidc.org/index.php/journal/article/view/18099 |
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