HYPOALBUMINEMIA, GLYCEMIA AND LEUKOCYTOSIS IN THE PATHOGENESIS OF ACUTE POST-OPERATIVE RESPIRATORY FAILURE IN THE PATIENTS AFTER THORACIC SURGERY
Acute post-operative respiratory failure is a dangerous complication developing after thoracic surgery.The objective of the study: to assess the potential use of albuminemia, glycemia and leukocytosis as markers of acute post-operative respiratory failure after thoracic surgery.Subjects and methods....
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| Format: | Article |
| Language: | Russian |
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New Terra Publishing House
2018-11-01
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| Series: | Вестник анестезиологии и реаниматологии |
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| Online Access: | https://www.vair-journal.com/jour/article/view/275 |
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| author | V. A. Zhikharev V. A. Porkhanov I. Yu. Sholin A. S. Bushuev Yu. P. Malyshev |
| author_facet | V. A. Zhikharev V. A. Porkhanov I. Yu. Sholin A. S. Bushuev Yu. P. Malyshev |
| author_sort | V. A. Zhikharev |
| collection | DOAJ |
| description | Acute post-operative respiratory failure is a dangerous complication developing after thoracic surgery.The objective of the study: to assess the potential use of albuminemia, glycemia and leukocytosis as markers of acute post-operative respiratory failure after thoracic surgery.Subjects and methods. A retrospective study was conducted enrolling 300 patients, which were divided into two groups – those who developed acute post-operative respiratory failure (n=150) and those who didn't (n=150). The post-operative level of glycemia and leukocytosis and the degree of albumin level reduction were comparatively analyzed in the early post-operative period.Results. The correlation was found between the degree of reduction of the post-operative albumin level and the ratio of PaO2/FiO2 – the strong inverse correlation (r = -0.9); the strong inverse correlation (r = -0.7) was found between the leukocytosis level and the ratio of PaO2/FiO2; while it was the median inverse correlation (r = -0.7) between glycemia level and the ratio of PaO2/FiO2; and between the degree of the post-operative reduction of albumin and glycemia level, it was the median direct correlation (r = 0.7).Conclusion. The higher levels of peri-operative glycemia and leucocytosis during the first 24 hours after the surgery and more intense reduction of the post-operative level of albumin demonstrate the intensity of stress-reaction to the surgical trauma and make valuable markers of the acute post-operative respiratory failure development in the patients after thoracic surgery. |
| format | Article |
| id | doaj-art-033eeda69c5342a79bb7650f1e2cc140 |
| institution | DOAJ |
| issn | 2078-5658 2541-8653 |
| language | Russian |
| publishDate | 2018-11-01 |
| publisher | New Terra Publishing House |
| record_format | Article |
| series | Вестник анестезиологии и реаниматологии |
| spelling | doaj-art-033eeda69c5342a79bb7650f1e2cc1402025-08-20T03:23:07ZrusNew Terra Publishing HouseВестник анестезиологии и реаниматологии2078-56582541-86532018-11-01155142110.21292/2078-5658-2018-15-5-14-21263HYPOALBUMINEMIA, GLYCEMIA AND LEUKOCYTOSIS IN THE PATHOGENESIS OF ACUTE POST-OPERATIVE RESPIRATORY FAILURE IN THE PATIENTS AFTER THORACIC SURGERYV. A. Zhikharev0V. A. Porkhanov1I. Yu. Sholin2A. S. Bushuev3Yu. P. Malyshev4S.V. Ochapovsky Research Institute – Regional Clinical Hospital no. 1.S.V. Ochapovsky Research Institute – Regional Clinical Hospital no. 1; Kuban State Medical University.S.V. Ochapovsky Research Institute – Regional Clinical Hospital no. 1.S.V. Ochapovsky Research Institute – Regional Clinical Hospital no. 1.S.V. Ochapovsky Research Institute – Regional Clinical Hospital no. 1.Acute post-operative respiratory failure is a dangerous complication developing after thoracic surgery.The objective of the study: to assess the potential use of albuminemia, glycemia and leukocytosis as markers of acute post-operative respiratory failure after thoracic surgery.Subjects and methods. A retrospective study was conducted enrolling 300 patients, which were divided into two groups – those who developed acute post-operative respiratory failure (n=150) and those who didn't (n=150). The post-operative level of glycemia and leukocytosis and the degree of albumin level reduction were comparatively analyzed in the early post-operative period.Results. The correlation was found between the degree of reduction of the post-operative albumin level and the ratio of PaO2/FiO2 – the strong inverse correlation (r = -0.9); the strong inverse correlation (r = -0.7) was found between the leukocytosis level and the ratio of PaO2/FiO2; while it was the median inverse correlation (r = -0.7) between glycemia level and the ratio of PaO2/FiO2; and between the degree of the post-operative reduction of albumin and glycemia level, it was the median direct correlation (r = 0.7).Conclusion. The higher levels of peri-operative glycemia and leucocytosis during the first 24 hours after the surgery and more intense reduction of the post-operative level of albumin demonstrate the intensity of stress-reaction to the surgical trauma and make valuable markers of the acute post-operative respiratory failure development in the patients after thoracic surgery.https://www.vair-journal.com/jour/article/view/275acute post-operative respiratory failurehypoalbuminemiahyperglycemialeukocytosislobectomy |
| spellingShingle | V. A. Zhikharev V. A. Porkhanov I. Yu. Sholin A. S. Bushuev Yu. P. Malyshev HYPOALBUMINEMIA, GLYCEMIA AND LEUKOCYTOSIS IN THE PATHOGENESIS OF ACUTE POST-OPERATIVE RESPIRATORY FAILURE IN THE PATIENTS AFTER THORACIC SURGERY Вестник анестезиологии и реаниматологии acute post-operative respiratory failure hypoalbuminemia hyperglycemia leukocytosis lobectomy |
| title | HYPOALBUMINEMIA, GLYCEMIA AND LEUKOCYTOSIS IN THE PATHOGENESIS OF ACUTE POST-OPERATIVE RESPIRATORY FAILURE IN THE PATIENTS AFTER THORACIC SURGERY |
| title_full | HYPOALBUMINEMIA, GLYCEMIA AND LEUKOCYTOSIS IN THE PATHOGENESIS OF ACUTE POST-OPERATIVE RESPIRATORY FAILURE IN THE PATIENTS AFTER THORACIC SURGERY |
| title_fullStr | HYPOALBUMINEMIA, GLYCEMIA AND LEUKOCYTOSIS IN THE PATHOGENESIS OF ACUTE POST-OPERATIVE RESPIRATORY FAILURE IN THE PATIENTS AFTER THORACIC SURGERY |
| title_full_unstemmed | HYPOALBUMINEMIA, GLYCEMIA AND LEUKOCYTOSIS IN THE PATHOGENESIS OF ACUTE POST-OPERATIVE RESPIRATORY FAILURE IN THE PATIENTS AFTER THORACIC SURGERY |
| title_short | HYPOALBUMINEMIA, GLYCEMIA AND LEUKOCYTOSIS IN THE PATHOGENESIS OF ACUTE POST-OPERATIVE RESPIRATORY FAILURE IN THE PATIENTS AFTER THORACIC SURGERY |
| title_sort | hypoalbuminemia glycemia and leukocytosis in the pathogenesis of acute post operative respiratory failure in the patients after thoracic surgery |
| topic | acute post-operative respiratory failure hypoalbuminemia hyperglycemia leukocytosis lobectomy |
| url | https://www.vair-journal.com/jour/article/view/275 |
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