Intraocular lens subluxation obstructing a glaucoma tube shunt after a Valsalva maneuver: a case report

Abstract Background Late subluxation of an intraocular lens (IOL) within the capsular bag is a rare complication of cataract surgery, primarily associated with progressive zonular weakening in conditions such as pseudoexfoliation syndrome, high myopia, prior vitreoretinal surgery, connective tissue...

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Main Authors: Ahnul Ha, Ki Tae Nam, Seongmi Kim, Ji Woong Chang, Jinho Jeong
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Ophthalmology
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Online Access:https://doi.org/10.1186/s12886-025-04253-y
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author Ahnul Ha
Ki Tae Nam
Seongmi Kim
Ji Woong Chang
Jinho Jeong
author_facet Ahnul Ha
Ki Tae Nam
Seongmi Kim
Ji Woong Chang
Jinho Jeong
author_sort Ahnul Ha
collection DOAJ
description Abstract Background Late subluxation of an intraocular lens (IOL) within the capsular bag is a rare complication of cataract surgery, primarily associated with progressive zonular weakening in conditions such as pseudoexfoliation syndrome, high myopia, prior vitreoretinal surgery, connective tissue disorders, or ocular trauma. While IOL-capsular bag subluxation is well-documented, its impact on glaucoma drainage devices remains poorly understood. We present a rare case of Valsalva-induced IOL subluxation obstructing an Ahmed glaucoma valve, resulting in acute intraocular pressure (IOP) elevation in a patient with pseudoexfoliative glaucoma. Case presentation A 66-year-old man with pseudoexfoliative glaucoma underwent uneventful phacoemulsification with IOL implantation in his left eye in 2013. He subsequently required trabeculectomy in 2015 and later an Ahmed glaucoma valve implantation due to uncontrolled IOP (38 mmHg). Postoperatively, his IOP remained stable (8–10 mmHg) without medication. Six months postoperatively, the patient developed persistent visual deterioration and ocular pain, which began three days after a severe coughing episode. Examination revealed a best-corrected visual acuity of 20/100 and IOP of 32 mmHg. Slit-lamp biomicroscopy demonstrated superior IOL subluxation, with the displaced IOL pushing the iris forward and resulting in obstruction of the Ahmed tube tip by the iris. Intraoperatively, the IOL was repositioned without posterior vitrectomy, restoring tube patency and IOL centration. Postoperatively, IOP normalized to 9 mmHg, and best-corrected visual acuity remained 20/100. Two months post-repositioning, IOP remained stable at 12 mmHg, with no further IOL displacement or tube obstruction. Conclusions This case highlights an uncommon mechanism of glaucoma tube obstruction caused by Valsalva-induced IOL subluxation. While common causes of glaucoma drainage devices obstruction include vitreous prolapse, inflammatory debris, and tube malposition, clinicians should recognize IOL subluxation as a potential cause of mechanical blockage. Given the progressive nature of zonular instability in pseudoexfoliation, close monitoring of IOL position, IOP, and tube function is crucial.
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spelling doaj-art-033d0179483846a68ff6c70c0c256b2e2025-08-20T03:42:30ZengBMCBMC Ophthalmology1471-24152025-07-012511510.1186/s12886-025-04253-yIntraocular lens subluxation obstructing a glaucoma tube shunt after a Valsalva maneuver: a case reportAhnul Ha0Ki Tae Nam1Seongmi Kim2Ji Woong Chang3Jinho Jeong4Department of Ophthalmology, Jeju National University HospitalDepartment of Ophthalmology, Jeju National University HospitalDepartment of Ophthalmology, Jeju National University HospitalDepartment of Ophthalmology, Jeju National University HospitalDepartment of Ophthalmology, Jeju National University HospitalAbstract Background Late subluxation of an intraocular lens (IOL) within the capsular bag is a rare complication of cataract surgery, primarily associated with progressive zonular weakening in conditions such as pseudoexfoliation syndrome, high myopia, prior vitreoretinal surgery, connective tissue disorders, or ocular trauma. While IOL-capsular bag subluxation is well-documented, its impact on glaucoma drainage devices remains poorly understood. We present a rare case of Valsalva-induced IOL subluxation obstructing an Ahmed glaucoma valve, resulting in acute intraocular pressure (IOP) elevation in a patient with pseudoexfoliative glaucoma. Case presentation A 66-year-old man with pseudoexfoliative glaucoma underwent uneventful phacoemulsification with IOL implantation in his left eye in 2013. He subsequently required trabeculectomy in 2015 and later an Ahmed glaucoma valve implantation due to uncontrolled IOP (38 mmHg). Postoperatively, his IOP remained stable (8–10 mmHg) without medication. Six months postoperatively, the patient developed persistent visual deterioration and ocular pain, which began three days after a severe coughing episode. Examination revealed a best-corrected visual acuity of 20/100 and IOP of 32 mmHg. Slit-lamp biomicroscopy demonstrated superior IOL subluxation, with the displaced IOL pushing the iris forward and resulting in obstruction of the Ahmed tube tip by the iris. Intraoperatively, the IOL was repositioned without posterior vitrectomy, restoring tube patency and IOL centration. Postoperatively, IOP normalized to 9 mmHg, and best-corrected visual acuity remained 20/100. Two months post-repositioning, IOP remained stable at 12 mmHg, with no further IOL displacement or tube obstruction. Conclusions This case highlights an uncommon mechanism of glaucoma tube obstruction caused by Valsalva-induced IOL subluxation. While common causes of glaucoma drainage devices obstruction include vitreous prolapse, inflammatory debris, and tube malposition, clinicians should recognize IOL subluxation as a potential cause of mechanical blockage. Given the progressive nature of zonular instability in pseudoexfoliation, close monitoring of IOL position, IOP, and tube function is crucial.https://doi.org/10.1186/s12886-025-04253-yAhmed glaucoma valveGlaucoma drainage deviceIntraocular lens subluxationPseudoexfoliative glaucoma
spellingShingle Ahnul Ha
Ki Tae Nam
Seongmi Kim
Ji Woong Chang
Jinho Jeong
Intraocular lens subluxation obstructing a glaucoma tube shunt after a Valsalva maneuver: a case report
BMC Ophthalmology
Ahmed glaucoma valve
Glaucoma drainage device
Intraocular lens subluxation
Pseudoexfoliative glaucoma
title Intraocular lens subluxation obstructing a glaucoma tube shunt after a Valsalva maneuver: a case report
title_full Intraocular lens subluxation obstructing a glaucoma tube shunt after a Valsalva maneuver: a case report
title_fullStr Intraocular lens subluxation obstructing a glaucoma tube shunt after a Valsalva maneuver: a case report
title_full_unstemmed Intraocular lens subluxation obstructing a glaucoma tube shunt after a Valsalva maneuver: a case report
title_short Intraocular lens subluxation obstructing a glaucoma tube shunt after a Valsalva maneuver: a case report
title_sort intraocular lens subluxation obstructing a glaucoma tube shunt after a valsalva maneuver a case report
topic Ahmed glaucoma valve
Glaucoma drainage device
Intraocular lens subluxation
Pseudoexfoliative glaucoma
url https://doi.org/10.1186/s12886-025-04253-y
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