Accurate Delivery of Mesenchymal Stem Cell Spheroids With Platelet‐Rich Fibrin Shield: Enhancing Survival and Repair Functions of Sp‐MSCs in Diabetic Wound Healing

Accurate Delivery of Mesenchymal Stem Cell Spheroids With Platelet‐Rich Fibrin Shield: Enhancing Survival and Repair Functions of Sp‐MSCs in Diabetic Wound Healing

Abstract Diabetic wound is a significant clinical challenge, and stem cell therapy has shown great potential. This study explores the role of mesenchymal stem cell (MSC) spheroids (Sp‐MSCs) in healing diabetic wounds and the use of autologous plasma‐rich platelet fibrin (PRF) as a scaffold for Sp‐MS...

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Main Authors: Jinglve Zhang, Wenqing Xu, Yutian Xiao, Dingheng Su, Yusheng He, Huohong Yang, Yixin Xie, Xiaofang Wang, Ren‐He Xu, Shaorong Lei, Dingyu Wu
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:Advanced Science
Subjects:
cell spheroid
diabetic wound
mesenchymal stem cell
platelet‐rich fiber
ROS protection
Online Access:https://doi.org/10.1002/advs.202413430
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