Design and fabrication of a realistic anthropomorphic heterogeneous head phantom for MR purposes.

<h4>Objective</h4>The purpose of this study is to design an anthropomorphic heterogeneous head phantom that can be used for MRI and other electromagnetic applications.<h4>Materials and methods</h4>An eight compartment, physical anthropomorphic head phantom was developed from...

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Main Authors: Sossena Wood, Narayanan Krishnamurthy, Tales Santini, Shailesh B Raval, Nadim Farhat, John Andy Holmes, Tamer S Ibrahim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0183168&type=printable
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author Sossena Wood
Narayanan Krishnamurthy
Tales Santini
Shailesh B Raval
Nadim Farhat
John Andy Holmes
Tamer S Ibrahim
author_facet Sossena Wood
Narayanan Krishnamurthy
Tales Santini
Shailesh B Raval
Nadim Farhat
John Andy Holmes
Tamer S Ibrahim
author_sort Sossena Wood
collection DOAJ
description <h4>Objective</h4>The purpose of this study is to design an anthropomorphic heterogeneous head phantom that can be used for MRI and other electromagnetic applications.<h4>Materials and methods</h4>An eight compartment, physical anthropomorphic head phantom was developed from a 3T MRI dataset of a healthy male. The designed phantom was successfully built and preliminarily evaluated through an application that involves electromagnetic-tissue interactions: MRI (due to it being an available resource). The developed phantom was filled with media possessing electromagnetic constitutive parameters that correspond to biological tissues at ~297 MHz. A preliminary comparison between an in-vivo human volunteer (based on whom the anthropomorphic head phantom was created) and various phantoms types, one being the anthropomorphic heterogeneous head phantom, were performed using a 7 Tesla human MRI scanner.<h4>Results</h4>Echo planar imaging was performed and minimal ghosting and fluctuations were observed using the proposed anthropomorphic phantom. The magnetic field distributions (during MRI experiments at 7 Tesla) and the scattering parameter (measured using a network analyzer) were most comparable between the anthropomorphic heterogeneous head phantom and an in-vivo human volunteer.<h4>Conclusion</h4>The developed anthropomorphic heterogeneous head phantom can be used as a resource to various researchers in applications that involve electromagnetic-biological tissue interactions such as MRI.
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spelling doaj-art-0336c44481584ecabbff697fcd1ba6912025-08-20T02:45:30ZengPublic Library of Science (PLoS)PLoS ONE1932-62032017-01-01128e018316810.1371/journal.pone.0183168Design and fabrication of a realistic anthropomorphic heterogeneous head phantom for MR purposes.Sossena WoodNarayanan KrishnamurthyTales SantiniShailesh B RavalNadim FarhatJohn Andy HolmesTamer S Ibrahim<h4>Objective</h4>The purpose of this study is to design an anthropomorphic heterogeneous head phantom that can be used for MRI and other electromagnetic applications.<h4>Materials and methods</h4>An eight compartment, physical anthropomorphic head phantom was developed from a 3T MRI dataset of a healthy male. The designed phantom was successfully built and preliminarily evaluated through an application that involves electromagnetic-tissue interactions: MRI (due to it being an available resource). The developed phantom was filled with media possessing electromagnetic constitutive parameters that correspond to biological tissues at ~297 MHz. A preliminary comparison between an in-vivo human volunteer (based on whom the anthropomorphic head phantom was created) and various phantoms types, one being the anthropomorphic heterogeneous head phantom, were performed using a 7 Tesla human MRI scanner.<h4>Results</h4>Echo planar imaging was performed and minimal ghosting and fluctuations were observed using the proposed anthropomorphic phantom. The magnetic field distributions (during MRI experiments at 7 Tesla) and the scattering parameter (measured using a network analyzer) were most comparable between the anthropomorphic heterogeneous head phantom and an in-vivo human volunteer.<h4>Conclusion</h4>The developed anthropomorphic heterogeneous head phantom can be used as a resource to various researchers in applications that involve electromagnetic-biological tissue interactions such as MRI.https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0183168&type=printable
spellingShingle Sossena Wood
Narayanan Krishnamurthy
Tales Santini
Shailesh B Raval
Nadim Farhat
John Andy Holmes
Tamer S Ibrahim
Design and fabrication of a realistic anthropomorphic heterogeneous head phantom for MR purposes.
PLoS ONE
title Design and fabrication of a realistic anthropomorphic heterogeneous head phantom for MR purposes.
title_full Design and fabrication of a realistic anthropomorphic heterogeneous head phantom for MR purposes.
title_fullStr Design and fabrication of a realistic anthropomorphic heterogeneous head phantom for MR purposes.
title_full_unstemmed Design and fabrication of a realistic anthropomorphic heterogeneous head phantom for MR purposes.
title_short Design and fabrication of a realistic anthropomorphic heterogeneous head phantom for MR purposes.
title_sort design and fabrication of a realistic anthropomorphic heterogeneous head phantom for mr purposes
url https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0183168&type=printable
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