Saccharomyces Boulardii and Saccharomyces Cerevisiae Improve Immunity in Broilers Vaccinated Against Pasteurella Multocida and Salmonella Gallinarum
ABSTRACT This study evaluated the impact of dietary Saccharomyces boulardii and Saccharomyces cerevisiae on the immunity of birds vaccinated against Pasteurella multocida and Salmonella gallinarum. A total of 105 male Cobb 500 broilers were divided into four groups: T1 (vaccinated, no supplement, n...
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Fundação APINCO de Ciência e Tecnologia Avícolas
2025-02-01
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| Series: | Brazilian Journal of Poultry Science |
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| author | C Von Mühlen NL Conrad AP Roll RC Dias FPL Leite CD Corcini AS Varela Junior VFB Roll |
| author_facet | C Von Mühlen NL Conrad AP Roll RC Dias FPL Leite CD Corcini AS Varela Junior VFB Roll |
| author_sort | C Von Mühlen |
| collection | DOAJ |
| description | ABSTRACT This study evaluated the impact of dietary Saccharomyces boulardii and Saccharomyces cerevisiae on the immunity of birds vaccinated against Pasteurella multocida and Salmonella gallinarum. A total of 105 male Cobb 500 broilers were divided into four groups: T1 (vaccinated, no supplement, n = 30), T2 (vaccinated, S. boulardii supplement, n = 30), T3 (vaccinated, S. cerevisiae supplement, n = 30), and T4 (non-vaccinated, no supplement, n = 15). Chickens received a corn-soy diet with 1x107 CFU/g of S. boulardii or S. cerevisiae for 42 days. Immune response was assessed by indirect ELISA and leukocyte counts. At 21 days, both supplemented groups showed significantly higher IgY levels than the vaccinated control (p < 0.05). S. boulardii supplementation increased lymphocytes (p = 0.003) and decreased heterophils (p=0.004), while S. cerevisiae had no significant effect. The heterophil/lymphocyte ratio decreased by respectively 23.4% and 32.8% in the S. cerevisiae and S. boulardii groups at 42 days, with no changes at 21 days. These results indicate that S. boulardii and S. cerevisiae can boost immunity and overall health in broilers. |
| format | Article |
| id | doaj-art-0331a455d15e4f289f2e82eefacab3c7 |
| institution | Kabale University |
| issn | 1806-9061 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Fundação APINCO de Ciência e Tecnologia Avícolas |
| record_format | Article |
| series | Brazilian Journal of Poultry Science |
| spelling | doaj-art-0331a455d15e4f289f2e82eefacab3c72025-02-11T07:42:57ZengFundação APINCO de Ciência e Tecnologia AvícolasBrazilian Journal of Poultry Science1806-90612025-02-0126410.1590/1806-9061-2024-1993Saccharomyces Boulardii and Saccharomyces Cerevisiae Improve Immunity in Broilers Vaccinated Against Pasteurella Multocida and Salmonella GallinarumC Von Mühlenhttps://orcid.org/0009-0009-4064-5309NL Conradhttps://orcid.org/0000-0001-7573-0794AP Rollhttps://orcid.org/0000-0002-0671-4675RC Diashttps://orcid.org/0000-0001-9420-2233FPL Leitehttps://orcid.org/0000-0003-0941-7286CD Corcinihttps://orcid.org/0000-0001-5683-7801AS Varela Juniorhttps://orcid.org/0000-0003-4901-5118VFB Rollhttps://orcid.org/0000-0002-4928-0299ABSTRACT This study evaluated the impact of dietary Saccharomyces boulardii and Saccharomyces cerevisiae on the immunity of birds vaccinated against Pasteurella multocida and Salmonella gallinarum. A total of 105 male Cobb 500 broilers were divided into four groups: T1 (vaccinated, no supplement, n = 30), T2 (vaccinated, S. boulardii supplement, n = 30), T3 (vaccinated, S. cerevisiae supplement, n = 30), and T4 (non-vaccinated, no supplement, n = 15). Chickens received a corn-soy diet with 1x107 CFU/g of S. boulardii or S. cerevisiae for 42 days. Immune response was assessed by indirect ELISA and leukocyte counts. At 21 days, both supplemented groups showed significantly higher IgY levels than the vaccinated control (p < 0.05). S. boulardii supplementation increased lymphocytes (p = 0.003) and decreased heterophils (p=0.004), while S. cerevisiae had no significant effect. The heterophil/lymphocyte ratio decreased by respectively 23.4% and 32.8% in the S. cerevisiae and S. boulardii groups at 42 days, with no changes at 21 days. These results indicate that S. boulardii and S. cerevisiae can boost immunity and overall health in broilers.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-635X2024000400316&lng=en&tlng=enBroilersimmune responseprobiotic supplementationSaccharomyces boulardiiSaccharomyces cerevisiae |
| spellingShingle | C Von Mühlen NL Conrad AP Roll RC Dias FPL Leite CD Corcini AS Varela Junior VFB Roll Saccharomyces Boulardii and Saccharomyces Cerevisiae Improve Immunity in Broilers Vaccinated Against Pasteurella Multocida and Salmonella Gallinarum Brazilian Journal of Poultry Science Broilers immune response probiotic supplementation Saccharomyces boulardii Saccharomyces cerevisiae |
| title | Saccharomyces Boulardii and Saccharomyces Cerevisiae Improve Immunity in Broilers Vaccinated Against Pasteurella Multocida and Salmonella Gallinarum |
| title_full | Saccharomyces Boulardii and Saccharomyces Cerevisiae Improve Immunity in Broilers Vaccinated Against Pasteurella Multocida and Salmonella Gallinarum |
| title_fullStr | Saccharomyces Boulardii and Saccharomyces Cerevisiae Improve Immunity in Broilers Vaccinated Against Pasteurella Multocida and Salmonella Gallinarum |
| title_full_unstemmed | Saccharomyces Boulardii and Saccharomyces Cerevisiae Improve Immunity in Broilers Vaccinated Against Pasteurella Multocida and Salmonella Gallinarum |
| title_short | Saccharomyces Boulardii and Saccharomyces Cerevisiae Improve Immunity in Broilers Vaccinated Against Pasteurella Multocida and Salmonella Gallinarum |
| title_sort | saccharomyces boulardii and saccharomyces cerevisiae improve immunity in broilers vaccinated against pasteurella multocida and salmonella gallinarum |
| topic | Broilers immune response probiotic supplementation Saccharomyces boulardii Saccharomyces cerevisiae |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-635X2024000400316&lng=en&tlng=en |
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