Multivariate protein landscape of host response in hospitalised patients with suspected infection in the emergency department

Multivariate protein landscape of host response in hospitalised patients with suspected infection in the emergency department

Abstract Suspected infection requiring hospitalisation has highly heterogenous presentation. Yet, variances in host response and its implications are largely unknown. In this multicentre cohort of 3802 individual patients presenting to the Emergency Department (ED) with suspected infection requiring...

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Main Authors: Pratik Sinha, Alexandra B. Spicer, Sivasubramanium Bhavani, Carlos López-Espina, Gregory L. Watson, Akhil Bhargava, Lee Schmalz, Shah Khan, Matthew D. Sims, Ashok V. Palagiri, Alon Dagan, Karthik V. Iyer, Matthew J. Crisp, Carmen DeMarco, Alexandra Halalau, Nicholas Maddens, Niko Kurtzman, Deesha Sarma, Falgun Gosai, Anwaruddin Syed, Saleem Azad, Aimee Espinosa, Francisco Davila, Hugo Davila, Neil Shadbeh Evans, Scott Smith, Bobby Reddy, Philip A. Verhoef, Matthew M. Churpek
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-62848-x
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