Successful treatment of rosacea by trephination combined with photodynamic therapy: A case report

Rosacea is a chronic, inflammatory dermatological condition primarily affecting the central face, including the cheeks, nose, chin, and forehead [1]. It presents with erythema, phymatous changes, papules, pustules, and telangiectasia. The pathogenesis of rosacea is still unknown. Patients often suff...

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Main Authors: YunMi Qiu, Ping Yang, Xingyun Zhao, Yingzhi Luo, Liming Wu, Jianbo Zhong
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Photodiagnosis and Photodynamic Therapy
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Online Access:http://www.sciencedirect.com/science/article/pii/S1572100024005064
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author YunMi Qiu
Ping Yang
Xingyun Zhao
Yingzhi Luo
Liming Wu
Jianbo Zhong
author_facet YunMi Qiu
Ping Yang
Xingyun Zhao
Yingzhi Luo
Liming Wu
Jianbo Zhong
author_sort YunMi Qiu
collection DOAJ
description Rosacea is a chronic, inflammatory dermatological condition primarily affecting the central face, including the cheeks, nose, chin, and forehead [1]. It presents with erythema, phymatous changes, papules, pustules, and telangiectasia. The pathogenesis of rosacea is still unknown. Patients often suffer from multiple symptoms of rosacea, requiring more precise assessments and individualized therapies [2]. 5-Aminolevulinic acid photodynamic therapy (ALA-PDT) has shown promise as a safe and effective treatment for rosacea [3], especially in patients with multiple subtypes. We report a successful treatment involving a 46-year-old male patient with erythematotelangiectatic rosacea and phymatous changes using trephination combined with photodynamic therapy (PDT), improving quality of life without recurrence during the 9-month follow-up period.
format Article
id doaj-art-0322a4ec90ed43d39e4da4d4e4ad7daa
institution Kabale University
issn 1572-1000
language English
publishDate 2025-02-01
publisher Elsevier
record_format Article
series Photodiagnosis and Photodynamic Therapy
spelling doaj-art-0322a4ec90ed43d39e4da4d4e4ad7daa2025-02-01T04:11:49ZengElsevierPhotodiagnosis and Photodynamic Therapy1572-10002025-02-0151104470Successful treatment of rosacea by trephination combined with photodynamic therapy: A case reportYunMi Qiu0Ping Yang1Xingyun Zhao2Yingzhi Luo3Liming Wu4Jianbo Zhong5Department of Dermatology, Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University Hangzhou, Zhejiang, 310000, ChinaDepartment of Dermatology, Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University Hangzhou, Zhejiang, 310000, ChinaDepartment of Dermatology, Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University Hangzhou, Zhejiang, 310000, ChinaDepartment of Dermatology, Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University Hangzhou, Zhejiang, 310000, ChinaDepartment of Dermatology, Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University Hangzhou, Zhejiang, 310000, ChinaCorresponding author at: Department of Dermatology, Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University, No.261, Huansha Road, Hangzhou, PR China.; Department of Dermatology, Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University Hangzhou, Zhejiang, 310000, ChinaRosacea is a chronic, inflammatory dermatological condition primarily affecting the central face, including the cheeks, nose, chin, and forehead [1]. It presents with erythema, phymatous changes, papules, pustules, and telangiectasia. The pathogenesis of rosacea is still unknown. Patients often suffer from multiple symptoms of rosacea, requiring more precise assessments and individualized therapies [2]. 5-Aminolevulinic acid photodynamic therapy (ALA-PDT) has shown promise as a safe and effective treatment for rosacea [3], especially in patients with multiple subtypes. We report a successful treatment involving a 46-year-old male patient with erythematotelangiectatic rosacea and phymatous changes using trephination combined with photodynamic therapy (PDT), improving quality of life without recurrence during the 9-month follow-up period.http://www.sciencedirect.com/science/article/pii/S1572100024005064RosaceaPhotodynamic therapyTrephinationDermatoscopy
spellingShingle YunMi Qiu
Ping Yang
Xingyun Zhao
Yingzhi Luo
Liming Wu
Jianbo Zhong
Successful treatment of rosacea by trephination combined with photodynamic therapy: A case report
Photodiagnosis and Photodynamic Therapy
Rosacea
Photodynamic therapy
Trephination
Dermatoscopy
title Successful treatment of rosacea by trephination combined with photodynamic therapy: A case report
title_full Successful treatment of rosacea by trephination combined with photodynamic therapy: A case report
title_fullStr Successful treatment of rosacea by trephination combined with photodynamic therapy: A case report
title_full_unstemmed Successful treatment of rosacea by trephination combined with photodynamic therapy: A case report
title_short Successful treatment of rosacea by trephination combined with photodynamic therapy: A case report
title_sort successful treatment of rosacea by trephination combined with photodynamic therapy a case report
topic Rosacea
Photodynamic therapy
Trephination
Dermatoscopy
url http://www.sciencedirect.com/science/article/pii/S1572100024005064
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AT yingzhiluo successfultreatmentofrosaceabytrephinationcombinedwithphotodynamictherapyacasereport
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