Rotation errors in path integration are associated with Alzheimer’s disease tau pathology: a cross-sectional study

Rotation errors in path integration are associated with Alzheimer’s disease tau pathology: a cross-sectional study

Abstract Background Early Alzheimer’s disease diagnosis is crucial for preventive therapy development. Standard neuropsychological evaluation does not identify clinically normal individuals with brain amyloidosis, the first stage of the pathology, defined as preclinical Alzheimer’s disease. Spatial...

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Main Authors: Lise Colmant, Lisa Quenon, Lara Huyghe, Adrian Ivanoiu, Thomas Gérard, Renaud Lhommel, Pauline Coppens, Yasmine Salman, Vincent Malotaux, Laurence Dricot, Lukas Kunz, Nikolai Axmacher, Philippe Lefèvre, Bernard Hanseeuw
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Alzheimer’s Research & Therapy
Subjects:
Spatial navigation
Path integration
Alzheimer’s disease
Early diagnosis
Tau pathology
Online Access:https://doi.org/10.1186/s13195-025-01679-w
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