Echography in the evaluation of the severity of ischemia-reperfusion injuries of a liver transplant
Objective: to study the role of echographic techniques in the evaluation of hemodynamic and structural changes in a liver transplant (LT) in ischemia-reperfusion injuries (IRI).Materials and methods. The results of an echographic follow-up were analyzed in 122 patients who had undergone orthotopic l...
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| Main Author: | |
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| Format: | Article |
| Language: | English |
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N.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare Department
2018-08-01
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| Series: | Трансплантология (Москва) |
| Subjects: | |
| Online Access: | https://www.jtransplantologiya.ru/jour/article/view/287 |
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| Summary: | Objective: to study the role of echographic techniques in the evaluation of hemodynamic and structural changes in a liver transplant (LT) in ischemia-reperfusion injuries (IRI).Materials and methods. The results of an echographic follow-up were analyzed in 122 patients who had undergone orthotopic liver transplantation in 2005 to 2010.Results. A high-resistance flow pattern was more frequently recorded in the arterial bed of LT within the first 24 postoperative hours. On day 3, there were negative changes as an increased resistance index at the level of the hepatic artery or its branches in 35% of the patients. Transient postischemic structural changes in the grafted organ were diagnosed in 42.3% of all the examinees; formation of large focal necroses was found in 28%. Mortality in patients with transient edema of the hepatic parenchyma was 4.5%. In the group of recipients who had been diagnosed as having large focal hepatic parenchymal necroses, mortality was 29.6%. Liver retransplantation was carried out in 10% of the patients because of graft dysfunction.Conclusion. According to the echographic findings, LT hemodynamic and structural changes as a sequel of prior IRI were revealed in the overwhelming majority of recipients. Ultrasound follow-up monitoring is a reliable tool for assessing the severity of LT injuries and risk factors for poor outcome. |
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| ISSN: | 2074-0506 2542-0909 |