Retrospective Gauging of Survival Rate and Clinical and Radiological Changes Following Regenerative Periodontal Therapy in Endodontic-Periodontal Lesions
Background: Endodontic-periodontal lesions present an open wound that might need surgical management using the GTR (guided tissue regeneration) to be managed using a combined approach. Aim: To assess the survival rate and clinical and radiological changes following regenerative periodontal therapy i...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2025-05-01
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| Series: | Journal of Pharmacy and Bioallied Sciences |
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| Online Access: | https://journals.lww.com/10.4103/jpbs.jpbs_29_25 |
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| author | Sneha Suresh Sandeep Kashyap Treena Kabiraj Kumar Abhishek Rosy Kumari Leena Hari |
| author_facet | Sneha Suresh Sandeep Kashyap Treena Kabiraj Kumar Abhishek Rosy Kumari Leena Hari |
| author_sort | Sneha Suresh |
| collection | DOAJ |
| description | Background:
Endodontic-periodontal lesions present an open wound that might need surgical management using the GTR (guided tissue regeneration) to be managed using a combined approach.
Aim:
To assess the survival rate and clinical and radiological changes following regenerative periodontal therapy in endodontic-periodontal lesions.
Methods:
The study assessed 104 cases in 82 subjects with a minimum 2-year follow-up. Following scaling and root planning with/without endodontic management, regenerative procedures using DBBM with 10% collagen (Group I) or DBBM with collagen membrane (Group II) were done. radiographic bone gain, mobility, relative clinical attachment levels, gingival recession, probing pocket depth, bleeding on probing, and plaque index changes were assessed.
Results:
In both groups, radiographic bone gains and improved clinical parameters were seen. Greater, but statistically nonsignificant probing depth reduction was seen in the DBBM + 10% collagen group compared to the DBBM + collagen membrane group with 4.54 ± 1.04 mm and 4.06 ± 0.80 mm respectively. Comparable radiographic bone gain was seen in Groups I and II with 5.13 ± 1.52 mm and 5.33 ± 1.82 mm. A 92.33% 5-year survival rate was reported following the regenerative surgery.
Conclusions:
Improved radiographic bone and clinical attachment levels are seen following regenerative procedures with DBBM with 10% collagen in endodontic-periodontal lesions. Strict supportive periodontal therapy and oral hygiene can help maintain the successful results of regenerative medicine. |
| format | Article |
| id | doaj-art-0313d563d9d04483b2aca45d44b38d2a |
| institution | Kabale University |
| issn | 0976-4879 0975-7406 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Pharmacy and Bioallied Sciences |
| spelling | doaj-art-0313d563d9d04483b2aca45d44b38d2a2025-08-20T03:24:40ZengWolters Kluwer Medknow PublicationsJournal of Pharmacy and Bioallied Sciences0976-48790975-74062025-05-0117Suppl 1S748S75010.4103/jpbs.jpbs_29_25Retrospective Gauging of Survival Rate and Clinical and Radiological Changes Following Regenerative Periodontal Therapy in Endodontic-Periodontal LesionsSneha SureshSandeep KashyapTreena KabirajKumar AbhishekRosy KumariLeena HariBackground: Endodontic-periodontal lesions present an open wound that might need surgical management using the GTR (guided tissue regeneration) to be managed using a combined approach. Aim: To assess the survival rate and clinical and radiological changes following regenerative periodontal therapy in endodontic-periodontal lesions. Methods: The study assessed 104 cases in 82 subjects with a minimum 2-year follow-up. Following scaling and root planning with/without endodontic management, regenerative procedures using DBBM with 10% collagen (Group I) or DBBM with collagen membrane (Group II) were done. radiographic bone gain, mobility, relative clinical attachment levels, gingival recession, probing pocket depth, bleeding on probing, and plaque index changes were assessed. Results: In both groups, radiographic bone gains and improved clinical parameters were seen. Greater, but statistically nonsignificant probing depth reduction was seen in the DBBM + 10% collagen group compared to the DBBM + collagen membrane group with 4.54 ± 1.04 mm and 4.06 ± 0.80 mm respectively. Comparable radiographic bone gain was seen in Groups I and II with 5.13 ± 1.52 mm and 5.33 ± 1.82 mm. A 92.33% 5-year survival rate was reported following the regenerative surgery. Conclusions: Improved radiographic bone and clinical attachment levels are seen following regenerative procedures with DBBM with 10% collagen in endodontic-periodontal lesions. Strict supportive periodontal therapy and oral hygiene can help maintain the successful results of regenerative medicine.https://journals.lww.com/10.4103/jpbs.jpbs_29_25bone lossendodontic-periodontal lesionsgtrregenerative endodontics |
| spellingShingle | Sneha Suresh Sandeep Kashyap Treena Kabiraj Kumar Abhishek Rosy Kumari Leena Hari Retrospective Gauging of Survival Rate and Clinical and Radiological Changes Following Regenerative Periodontal Therapy in Endodontic-Periodontal Lesions Journal of Pharmacy and Bioallied Sciences bone loss endodontic-periodontal lesions gtr regenerative endodontics |
| title | Retrospective Gauging of Survival Rate and Clinical and Radiological Changes Following Regenerative Periodontal Therapy in Endodontic-Periodontal Lesions |
| title_full | Retrospective Gauging of Survival Rate and Clinical and Radiological Changes Following Regenerative Periodontal Therapy in Endodontic-Periodontal Lesions |
| title_fullStr | Retrospective Gauging of Survival Rate and Clinical and Radiological Changes Following Regenerative Periodontal Therapy in Endodontic-Periodontal Lesions |
| title_full_unstemmed | Retrospective Gauging of Survival Rate and Clinical and Radiological Changes Following Regenerative Periodontal Therapy in Endodontic-Periodontal Lesions |
| title_short | Retrospective Gauging of Survival Rate and Clinical and Radiological Changes Following Regenerative Periodontal Therapy in Endodontic-Periodontal Lesions |
| title_sort | retrospective gauging of survival rate and clinical and radiological changes following regenerative periodontal therapy in endodontic periodontal lesions |
| topic | bone loss endodontic-periodontal lesions gtr regenerative endodontics |
| url | https://journals.lww.com/10.4103/jpbs.jpbs_29_25 |
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